关注
Simon Giroux
Simon Giroux
Vertex Pharmaceuticals, Harvard University, Université de Montréal
在 vrtx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Efficient allyl to propenyl isomerization in functionally diverse compounds with a thermally modified Grubbs second-generation catalyst
S Hanessian, S Giroux, A Larsson
Organic Letters 8 (24), 5481-5484, 2006
1832006
Application of conformation design in acyclic stereoselection: total synthesis of borrelidin as the crystalline benzene solvate
S Hanessian, Yang, S Giroux, V Mascitti, J Ma, F Raeppel
Journal of the American Chemical Society 125 (45), 13784-13792, 2003
1042003
Base-metal-catalyzed olefin isomerization reactions
X Liu, B Li, Q Liu
Synthesis 51 (06), 1293-1310, 2019
902019
Design and strategy in organic synthesis
S Hanessian, S Giroux, BL Merner
Wiley-VCH Verlag GmbH, 2012
672012
The iterative synthesis of acyclic deoxypropionate units and their implication in polyketide-derived natural products
S Hanessian, S Giroux, V Mascitti
Synthesis 2006 (07), 1057-1076, 2006
552006
Dna-pk inhibitors
PS Charifson, KM Cottrell, H Deng, JP Duffy, H Gao, S Giroux, J Green, ...
US Patent 9,376,448, 2016
482016
Overcoming acquired resistance to kinase inhibition: the cases of EGFR, ALK and BRAF
S Giroux
Bioorganic & medicinal chemistry letters 23 (2), 394-401, 2013
452013
C–H Functionalization of heteroarenes using unactivated alkyl halides through visible-light photoredox catalysis under basic conditions
NB Bissonnette, MJ Boyd, GD May, S Giroux, P Nuhant
The Journal of Organic Chemistry 83 (18), 10933-10940, 2018
412018
Stereocontrolled synthesis of dafachronic acid A, the ligand for the DAF-12 nuclear receptor of Caenorhabditis elegans
S Giroux, EJ Corey
Journal of the American Chemical Society 129 (32), 9866-9867, 2007
412007
Total synthesis and structural confirmation of (+)-longicin
S Hanessian, S Giroux, M Buffat
Organic Letters 7 (18), 3989-3992, 2005
402005
Total synthesis of the cytotoxic cyclodepsipeptide (-)-doliculide: The “ester” effect in acyclic 1, 3-induction of deoxypropionates
S Hanessian, V Mascitti, S Giroux
Proceedings of the National Academy of Sciences 101 (33), 11996-12001, 2004
372004
Dna-pk inhibitors
PS Charifson, KM Cottrell, H Deng, JP Duffy, H Gao, S Giroux, J Green, ...
US Patent 9,296,701, 2016
332016
Iterative synthesis of deoxypropionate units: The inductor effect in acyclic conformation design
S Hanessian, N Chahal, S Giroux
The Journal of Organic Chemistry 71 (19), 7403-7411, 2006
332006
Contemporary synthetic strategies towards secosteroids, abeo-steroids, and related triterpenes
F Noack, RC Heinze, P Heretsch
Synthesis 51 (10), 2039-2057, 2019
322019
DNA-PK inhibitors and uses thereof
PS Charifson, KM Cottrell, H Deng, JP Duffy, H Gao, S Giroux, J Green, ...
US Patent 9,925,188, 2018
282018
An Efficient, Stereocontrolled Synthesis of the 25-(R)-Diastereomer of Dafachronic Acid A from β-Ergosterol
S Giroux, EJ Corey
Organic Letters 10 (5), 801-802, 2008
282008
Palladium catalyzed hydrodefluorination of fluoro-(hetero) arenes
JJ Gair, RL Grey, S Giroux, MA Brodney
Organic letters 21 (7), 2482-2487, 2019
272019
Substituted quinoxaline DNA-PK inhibitors
JP Maxwell, PS Charifson, Q Tang, SM Ronkin, KL Jackson, AC Pierce, ...
US Patent 9,340,557, 2016
27*2016
Divergent Oxidative Couplings between Indoles and 2, 3-Dihydroxybenzoic Acid Derivatives for the Biomimetic Synthesis of Voacalgine A and Bipleiophylline
N Denizot, D Lachkar, C Kouklovsky, E Poupon, L Evanno, G Vincent
Synthesis 50 (21), 4229-4242, 2018
262018
Dna-pk inhibitors
JP Maxwell, PS Charifson, Q Tang, SM Ronkin, KL Jackson, AC Pierce, ...
US Patent 9,359,380, 2016
252016
系统目前无法执行此操作,请稍后再试。
文章 1–20