CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy AA Barkal, RE Brewer, M Markovic, M Kowarsky, SA Barkal, BW Zaro, ... Nature 572 (7769), 392-396, 2019 | 932 | 2019 |
O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease NP Marotta, YH Lin, YE Lewis, MR Ambroso, BW Zaro, MT Roth, ... Nature chemistry 7 (11), 913-920, 2015 | 280 | 2015 |
Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1 BW Zaro, YY Yang, HC Hang, MR Pratt Proceedings of the National Academy of Sciences 108 (20), 8146-8151, 2011 | 239 | 2011 |
Chemical proteomic map of dimethyl fumarate–sensitive cysteines in primary human T cells MM Blewett, J Xie, BW Zaro, KM Backus, A Altman, JR Teijaro, BF Cravatt Science signaling 9 (445), rs10-rs10, 2016 | 175 | 2016 |
Changes in Metabolic Chemical Reporter Structure Yield a Selective Probe of O-GlcNAc Modification KN Chuh, BW Zaro, F Piller, V Piller, MR Pratt Journal of the American Chemical Society 136 (35), 12283-12295, 2014 | 140 | 2014 |
An alkyne–aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells LA Bateman, BW Zaro, SM Miller, MR Pratt Journal of the American Chemical Society 135 (39), 14568-14573, 2013 | 90 | 2013 |
Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy Z Gurel, BW Zaro, MR Pratt, N Sheibani PloS one 9 (5), e95561, 2014 | 75 | 2014 |
Chemoproteomics reveals Toll-like receptor fatty acylation NM Chesarino, JC Hach, JL Chen, BW Zaro, MVS Rajaram, J Turner, ... BMC biology 12, 1-13, 2014 | 74 | 2014 |
The new chemical reporter 6-alkynyl-6-deoxy-GlcNAc reveals O-GlcNAc modification of the apoptotic caspases that can block the cleavage/activation of caspase-8 KN Chuh, AR Batt, BW Zaro, N Darabedian, NP Marotta, CK Brennan, ... Journal of the American Chemical Society 139 (23), 7872-7885, 2017 | 62 | 2017 |
Dimethyl fumarate disrupts human innate immune signaling by targeting the IRAK4–MyD88 complex BW Zaro, EV Vinogradova, DC Lazar, MM Blewett, RM Suciu, J Takaya, ... The Journal of Immunology 202 (9), 2737-2746, 2019 | 54 | 2019 |
The small molecule 2-azido-2-deoxy-glucose is a metabolic chemical reporter of O-GlcNAc modifications in mammalian cells, revealing an unexpected promiscuity of O-GlcNAc … BW Zaro, AR Batt, KN Chuh, MX Navarro, MR Pratt ACS chemical biology 12 (3), 787-794, 2017 | 53 | 2017 |
N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation LA Bateman, BW Zaro, KN Chuh, MR Pratt Chemical communications 49 (39), 4328-4330, 2013 | 49 | 2013 |
The Proteome‐Wide Potential for Reversible Covalency at Cysteine K Senkane, EV Vinogradova, RM Suciu, VM Crowley, BW Zaro, ... Angewandte Chemie 131 (33), 11507-11511, 2019 | 46 | 2019 |
Secreted fungal virulence effector triggers allergic inflammation via TLR4 EV Dang, S Lei, A Radkov, RF Volk, BW Zaro, HD Madhani Nature 608 (7921), 161-167, 2022 | 41 | 2022 |
Synthesis of dihydropyrimidinones/thiopyrimidinones: Nafion-Ga, an efficient “green” lewis acid catalyst for the biginelli reaction GKS Prakash, H Lau, C Panja, I Bychinskaya, SK Ganesh, B Zaro, ... Catalysis letters 144, 2012-2020, 2014 | 38 | 2014 |
Metabolically labile fumarate esters impart kinetic selectivity to irreversible inhibitors BW Zaro, LR Whitby, KM Lum, BF Cravatt Journal of the American Chemical Society 138 (49), 15841-15844, 2016 | 37 | 2016 |
Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells BW Zaro, JJ Noh, VL Mascetti, J Demeter, B George, M Zukowska, ... Elife 9, e62210, 2020 | 35 | 2020 |
Metabolic chemical reporters of glycans exhibit cell‐type‐selective metabolism and glycoprotein labeling AR Batt, BW Zaro, MX Navarro, MR Pratt ChemBioChem 18 (13), 1177-1182, 2017 | 28 | 2017 |
Chemical reporter for visualizing metabolic cross-talk between carbohydrate metabolism and protein modification BW Zaro, KN Chuh, MR Pratt ACS Chemical Biology 9 (9), 1991-1996, 2014 | 27 | 2014 |
O-acetylated chemical reporters of glycosylation can display metabolism-dependent background labeling of proteins but are generally reliable tools for the identification of … N Darabedian, B Yang, R Ding, G Cutolo, BW Zaro, CM Woo, MR Pratt Frontiers in Chemistry 8, 318, 2020 | 23 | 2020 |