Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection P Padmanabhan, R Desikan, N Dixit PLOS Computational Biology 16 (12), e1008461, 2020 | 131 | 2020 |
In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters AT Bademosi, E Lauwers, P Padmanabhan, L Odierna, YJ Chai, ... Nature communications 8, 13660, 2016 | 94 | 2016 |
Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles M Joensuu, P Padmanabhan, N Durisic, ATD Bademosi, ... Journal of Cell Biology 215 (2), 277-292, 2016 | 74 | 2016 |
Visualizing endocytic recycling and trafficking in live neurons by subdiffractional tracking of internalized molecules M Joensuu, R Martínez-Mármol, P Padmanabhan, NR Glass, N Durisic, ... Nature Protocols 12 (12), 2590, 2017 | 59 | 2017 |
Radial contractility of actomyosin rings facilitates axonal trafficking and structural stability T Wang, W Li, S Martin, A Papadopulos, M Joensuu, C Liu, A Jiang, ... Journal of Cell Biology 219 (5), 2020 | 57 | 2020 |
Modeling how antibody responses may determine the efficacy of COVID-19 vaccines P Padmanabhan, R Desikan, NM Dixit Nature Computational Science 2 (2), 123-131, 2022 | 46* | 2022 |
Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines P Padmanabhan, R Martínez-Mármol, D Xia, J Götz, FA Meunier eLife 8, e45040, 2019 | 44 | 2019 |
Super-resolution microscopy: a closer look at synaptic dysfunction in Alzheimer disease P Padmanabhan, A Kneynsberg, J Götz Nature Reviews Neuroscience, 1-18, 2021 | 42 | 2021 |
Emergent properties of the interferon-signalling network may underlie the success of hepatitis C treatment P Padmanabhan, U Garaigorta, NM Dixit Nature Communications 5 (1), 1-9, 2014 | 40 | 2014 |
Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies RS Gormal, P Padmanabhan, R Kasula, AT Bademosi, S Coakley, ... Proceedings of the National Academy of Sciences, 2020 | 36 | 2020 |
Need for speed: super-resolving the dynamic nanoclustering of syntaxin-1 at exocytic fusion sites P Padmanabhan, AT Bademosi, R Kasula, E Lauwers, P Verstreken, ... Neuropharmacology 169, 107554, 2020 | 30 | 2020 |
Increased B Cell Selection Stringency In Germinal Centers Can Explain Improved COVID-19 Vaccine Efficacies With Low Dose Prime or Delayed Boost AK Garg, S Mittal, P Padmanabhan, R Desikan, NM Dixit Frontiers in immunology 12, 776933, 2021 | 28 | 2021 |
Mathematical model of viral kinetics in vitro estimates the number of E2-CD81 complexes necessary for hepatitis C virus entry P Padmanabhan, NM Dixit PLoS computational biology 7 (12), e1002307, 2011 | 26 | 2011 |
Modelling how increased Cathepsin B/L and decreased TMPRSS2 usage for cell entry by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin … P Padmanabhan, NM Dixit Journal of Theoretical Biology, 111568, 2023 | 21* | 2023 |
Modeling Suggests a Mechanism of Synergy Between Hepatitis C Virus Entry Inhibitors and Drugs of Other Classes P Padmanabhan, NM Dixit CPT: Pharmacometrics & Systems Pharmacology 4 (8), 445-453, 2015 | 20 | 2015 |
Mechanistic Models of COVID-19: Insights into Disease Progression, Vaccines, and Therapeutics R Desikan, P Padmanabhan, AM Kierzek, PH van der Graaf International Journal of Antimicrobial Agents, 106606, 2022 | 19 | 2022 |
Opportunities and challenges in delivering biologics for Alzheimer’s disease by low-intensity ultrasound L Chen, E Cruz, L Oikari, P Padmanabhan, J Song, J Götz Advanced Drug Delivery Reviews, 114517, 2022 | 17 | 2022 |
Axon growth regulation by a bistable molecular switch P Padmanabhan, GJ Goodhill Proceedings of the Royal Society B: Biological Sciences 285 (1877), 20172618, 2018 | 13 | 2018 |
Opening of smaller toxin pores by lipid micelle formation R Desikan, P Padmanabhan, KG Ayappa Proceedings of the National Academy of Sciences 117 (10), 5107-5108, 2020 | 12 | 2020 |
Modelling how responsiveness to interferon improves interferon-free treatment of hepatitis C virus infection V Venugopal, P Padmanabhan, R Raja, NM Dixit PLOS Computational Biology 14 (7), e1006335, 2018 | 12 | 2018 |