Viral protease inhibitors J Anderson, C Schiffer, SK Lee, R Swanstrom Antiviral strategies, 85-110, 2009 | 172 | 2009 |
The choreography of HIV-1 proteolytic processing and virion assembly SK Lee, M Potempa, R Swanstrom Journal of Biological Chemistry 287 (49), 40867-40874, 2012 | 162 | 2012 |
A Strongly Transdominant Mutation in the Human Immunodeficiency Virus Type 1 gag Gene Defines an Achilles Heel in the Virus Life Cycle SK Lee, J Harris, R Swanstrom Journal of virology 83 (17), 8536-8543, 2009 | 98 | 2009 |
Context surrounding processing sites is crucial in determining cleavage rate of a subset of processing sites in HIV-1 Gag and Gag-Pro-Pol polyprotein precursors by viral protease SK Lee, M Potempa, M Kolli, A Özen, CA Schiffer, R Swanstrom Journal of Biological Chemistry 287 (16), 13279-13290, 2012 | 60 | 2012 |
Interplay between single resistance-associated mutations in the HIV-1 protease and viral infectivity, protease activity, and inhibitor sensitivity GJ Henderson, SK Lee, DM Irlbeck, J Harris, M Kline, E Pollom, N Parkin, ... Antimicrobial agents and chemotherapy 56 (2), 623-633, 2012 | 45 | 2012 |
In vitro analysis of an RNA binding site within the N-terminal 30 amino acids of the southern cowpea mosaic virus coat protein SK Lee, DL Hacker Virology 286 (2), 317-327, 2001 | 33 | 2001 |
Elucidating the interdependence of drug resistance from combinations of mutations DA Ragland, TW Whitfield, SK Lee, R Swanstrom, KB Zeldovich, ... Journal of chemical theory and computation 13 (11), 5671-5682, 2017 | 32 | 2017 |
Quantification of the latent HIV-1 reservoir using ultra deep sequencing and primer ID in a viral outgrowth assay SK Lee, S Zhou, PL Baldoni, E Spielvogel, NM Archin, MG Hudgens, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 74 (2), 221-228, 2017 | 31 | 2017 |
Long-range recombination gradient between HIV-1 subtypes B and C variants caused by sequence differences in the dimerization initiation signal region MPS Chin, SK Lee, J Chen, OA Nikolaitchik, DA Powell, MJ Fivash Jr, ... Journal of molecular biology 377 (5), 1324-1333, 2008 | 27 | 2008 |
Cooperative effect of gag proteins p12 and capsid during early events of murine leukemia virus replication SK Lee, K Nagashima, WS Hu Journal of virology 79 (7), 4159-4169, 2005 | 27 | 2005 |
HIV-1 protease uses bi-specific S2/S2′ subsites to optimize cleavage of two classes of target sites M Potempa, SK Lee, NK Yilmaz, EA Nalivaika, A Rogers, E Spielvogel, ... Journal of molecular biology 430 (24), 5182-5195, 2018 | 19 | 2018 |
The triple threat of HIV-1 protease inhibitors M Potempa, SK Lee, R Wolfenden, R Swanstrom The Future of HIV-1 Therapeutics: Resistance Is Futile?, 203-241, 2015 | 19 | 2015 |
A direct interaction with RNA dramatically enhances the catalytic activity of the HIV-1 protease in vitro M Potempa, E Nalivaika, D Ragland, SK Lee, CA Schiffer, R Swanstrom Journal of molecular biology 427 (14), 2360-2378, 2015 | 15 | 2015 |
Membrane activity of the southern cowpea mosaic virus coat protein: the role of basic amino acids, helix-forming potential, and lipid composition SK Lee, C Dabney-Smith, DL Hacker, BD Bruce Virology 291 (2), 299-310, 2001 | 15 | 2001 |
A sensitive assay using a native protein substrate for screening HIV-1 maturation inhibitors targeting the protease cleavage site between the matrix and capsid SK Lee, N Cheng, E Hull-Ryde, M Potempa, CA Schiffer, W Janzen, ... Biochemistry 52 (29), 4929-4940, 2013 | 13 | 2013 |
Capsid is an important determinant for functional complementation of murine leukemia virus and spleen necrosis virus Gag proteins SK Lee, V Boyko, WS Hu Virology 360 (2), 388-397, 2007 | 10 | 2007 |
Development of a novel screening strategy designed to discover a new class of HIV drugs N Cheng, SK Lee, PS Donover, M Reichman, CA Schiffer, EA Hull-Ryde, ... Journal of laboratory automation 19 (3), 297-303, 2014 | 8 | 2014 |
Assay to measure the latent reservoir of replication-competent HIV-1 in suppressed patients based on ultra deep sequencing SK Lee, S Zhou, N Archin, D Margolis, R Swanstrom Journal of the International Aids Society 18, 2015 | 2 | 2015 |
Structure-based design, synthesis, evaluation and x-ray crystal structure analysis of HIV-1 protease inhibitors with modified P1, P1'and P2'groups L Rusere, A Ali, G Lockbaum, SK Lee, R Swanstrom, C Schiffer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Deep sequencing analysis reveals novel resistance pathways to potent human immunodeficiency virus type 1 (HIV-1) protease inhibitors SK Lee, S Zhou, J Paulsen, CA Schiffer, R Swanstrom ANTIVIRAL THERAPY 19, A132-A132, 2014 | | 2014 |