Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life Z Peng, J Yan, X Fan, MJ Mizianty, B Xue, K Wang, G Hu, VN Uversky, ... Cellular and Molecular Life Sciences 72, 137-151, 2015 | 392 | 2015 |
Functional interrogation of DNA damage response variants with base editing screens R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ... Cell 184 (4), 1081-1097. e19, 2021 | 182 | 2021 |
Accurate prediction of disorder in protein chains with a comprehensive and empirically designed consensus X Fan, L Kurgan Journal of Biomolecular Structure and Dynamics 32 (3), 448-464, 2014 | 168 | 2014 |
Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis J Groenendyk, Z Peng, E Dudek, X Fan, MJ Mizianty, E Dufey, H Urra, ... Science signaling 7 (329), ra54-ra54, 2014 | 111 | 2014 |
Comprehensive overview and assessment of computational prediction of microRNA targets in animals X Fan, L Kurgan Briefings in bioinformatics 16 (5), 780-794, 2015 | 90 | 2015 |
The intrinsic disorder status of the human hepatitis C virus proteome X Fan, B Xue, PT Dolan, DJ LaCount, L Kurgan, VN Uversky Molecular BioSystems 10 (6), 1345-1363, 2014 | 67 | 2014 |
Genotype and defects in microtubule-based motility correlate with clinical severity in KIF1A-associated neurological disorder L Boyle, L Rao, S Kaur, X Fan, C Mebane, L Hamm, A Thornton, ... Human Genetics and Genomics Advances 2 (2), 2021 | 50 | 2021 |
Predicting functional effect of missense variants using graph attention neural networks H Zhang, MS Xu, X Fan, WK Chung, Y Shen Nature Machine Intelligence 4 (11), 1017-1028, 2022 | 42 | 2022 |
Covering complete proteomes with X-ray structures: a current snapshot MJ Mizianty, X Fan, J Yan, E Chalmers, C Woloschuk, A Joachimiak, ... Acta Crystallographica Section D: Biological Crystallography 70 (11), 2781-2793, 2014 | 38 | 2014 |
The Return of Actionable Variants Empirical (RAVE) Study, a Mayo Clinic genomic medicine implementation study: design and initial results IJ Kullo, J Olson, X Fan, M Jose, M Safarova, CR Breitkopf, E Winkler, ... Mayo Clinic Proceedings 93 (11), 1600-1610, 2018 | 34 | 2018 |
The genetic architecture of pediatric cardiomyopathy SM Ware, S Bhatnagar, PJ Dexheimer, JD Wilkinson, A Sridhar, X Fan, ... The American Journal of Human Genetics 109 (2), 282-298, 2022 | 33 | 2022 |
Genetic basis of hypercholesterolemia in adults S Saadatagah, M Jose, O Dikilitas, L Alhalabi, AA Miller, X Fan, JE Olson, ... NPJ genomic medicine 6 (1), 28, 2021 | 30 | 2021 |
Analyzing the effects of protecting osmolytes on solute–water interactions by solvatochromic comparison method: II. Globular proteins LA Ferreira, X Fan, PP Madeira, L Kurgan, VN Uversky, BY Zaslavsky Rsc Advances 5 (73), 59780-59791, 2015 | 30 | 2015 |
Common germline-somatic variant interactions in advanced urothelial cancer A Vosoughi, T Zhang, KS Shohdy, PJ Vlachostergios, DC Wilkes, ... Nature Communications 11 (1), 6195, 2020 | 28 | 2020 |
Structural features important for differences in protein partitioning in aqueous dextran–polyethylene glycol two-phase systems of different ionic compositions L Ferreira, X Fan, LM Mikheeva, PP Madeira, L Kurgan, VN Uversky, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (3), 694-704, 2014 | 28 | 2014 |
A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR MS Safarova, BA Satterfield, X Fan, EE Austin, Z Ye, L Bastarache, ... NPJ Genomic Medicine 4 (1), 3, 2019 | 27 | 2019 |
Clinical and genetic characterization of CACNA1A‐related disease AR Lipman, X Fan, Y Shen, WK Chung Clinical genetics 102 (4), 288-295, 2022 | 19 | 2022 |
Penetrance of breast cancer susceptibility genes from the eMERGE III network X Fan, J Wynn, N Shang, C Liu, A Fedotov, MLG Hallquist, AH Buchanan, ... JNCI Cancer Spectrum 5 (4), pkab044, 2021 | 19 | 2021 |
Clinical, neuroimaging and molecular characteristics of PPP2R5D-related neurodevelopmental disorders: an expanded series with functional characterisation and genotype–phenotype … N Oyama, P Vaneynde, S Reynhout, EM Pao, A Timms, X Fan, K Foss, ... Journal of Medical Genetics 60 (5), 511-522, 2023 | 18 | 2023 |
Detailed Clinical and Psychological Phenotype of the X-linked HNRNPH2-Related Neurodevelopmental Disorder JM Bain, O Thornburg, C Pan, D Rome-Martin, L Boyle, X Fan, ... Neurology: Genetics 7 (1), e551, 2021 | 18 | 2021 |