α-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model AL Matsuo, CR Figueiredo, DC Arruda, FV Pereira, JAB Scutti, ... Biochemical and biophysical research communications 411 (2), 449-454, 2011 | 239 | 2011 |
Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance EL Giddings, DP Champagne, MH Wu, JM Laffin, TM Thornton, ... Nature communications 12 (1), 2804, 2021 | 106 | 2021 |
NLRP3 inflammasome mediates aldosterone-induced vascular damage T Bruder-Nascimento, NS Ferreira, CZ Zanotto, F Ramalho, IO Pequeno, ... Circulation 134 (23), 1866-1880, 2016 | 105 | 2016 |
Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation L Barbier-Torres, KA Fortner, P Iruzubieta, TC Delgado, E Giddings, ... Nature communications 11 (1), 3360, 2020 | 104 | 2020 |
Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response FV Pereira, ACL Melo, JS Low, ÍA de Castro, TT Braga, DC Almeida, ... Oncotarget 9 (40), 25808, 2018 | 82 | 2018 |
A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells FA Serrano, AL Matsuo, PT Monteforte, A Bechara, SS Smaili, ... BMC cancer 11, 1-16, 2011 | 72 | 2011 |
β-Actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective … DC Arruda, LCP Santos, FM Melo, FV Pereira, CR Figueiredo, AL Matsuo, ... Journal of Biological Chemistry 287 (18), 14912-14922, 2012 | 50 | 2012 |
A new perspective: mitochondrial Stat3 as a regulator for lymphocyte function M Rincon, FV Pereira International journal of molecular sciences 19 (6), 1656, 2018 | 48 | 2018 |
Anti‐metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10 FM De Melo, CJM Braga, FV Pereira, JT Maricato, CST Origassa, ... Immunology and cell biology 93 (1), 86-98, 2015 | 38 | 2015 |
Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo CR Figueiredo, AL Matsuo, FV Pereira, AN Rabaca, CF Farias, N Girola, ... Pharmacognosy magazine 10 (Suppl 2), S363, 2014 | 38 | 2014 |
Role of SOCS-1 gene on melanoma cell growth and tumor development JAB Scutti, AL Matsuo, FV Pereira, MH Massaoka, CR Figueiredo, ... Translational oncology 4 (2), 101-109, 2011 | 36 | 2011 |
NLRP3 gain-of-function in CD4+ T lymphocytes ameliorates experimental autoimmune encephalomyelitis TT Braga, WN Brandao, H Azevedo, FF Terra, ACL Melo, FV Pereira, ... Clinical Science 133 (17), 1901-1916, 2019 | 29 | 2019 |
Co-administration of α-GalCer analog and TLR4 agonist induces robust CD8+ T-cell responses to PyCS protein and WT-1 antigen and activates memory-like effector NKT cells JG Coelho-dos-Reis, J Huang, T Tsao, FV Pereira, R Funakoshi, ... Clinical Immunology 168, 6-15, 2016 | 29 | 2016 |
Antitumor activity of kielmeyera coriacea leaf constituents in experimental melanoma, tested in vitro and in vivo in syngeneic mice CR Figueiredo, AL Matsuo, MH Massaoka, N Girola, RA Azevedo, ... Advanced pharmaceutical bulletin 4 (Suppl 1), 429, 2014 | 28 | 2014 |
A natural bacterial-derived product, the metalloprotease arazyme, inhibits metastatic murine melanoma by inducing MMP-8 cross-reactive antibodies FV Pereira, CA Ferreira-Guimaraes, T Paschoalin, JAB Scutti, FM Melo, ... PloS one 9 (4), e96141, 2014 | 26 | 2014 |
FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system FV Pereira, DC Arruda, CR Figueiredo, MH Massaoka, AL Matsuo, ... Clinics 68 (7), 1018-1027, 2013 | 26 | 2013 |
IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca2+ through the noncanonical STAT3 pathway F Valença-Pereira, Q Fang, IJ Marié, EL Giddings, KA Fortner, R Yang, ... Proceedings of the National Academy of Sciences 118 (37), e2103444118, 2021 | 25 | 2021 |
Sugarcane cystatin CaneCPI-4 inhibits melanoma growth by angiogenesis disruption JP Oliveira, HF Magliarelli, FV Pereira, A Gianotti, A Soares-Costa, ... J Cancer Sci Ther 3 (7), 161-167, 2011 | 25 | 2011 |
SOCS1 favors the epithelial-mesenchymal transition in melanoma, promotes tumor progression and prevents antitumor immunity by PD-L1 expression R Berzaghi, VSC Maia, FV Pereira, FM Melo, MS Guedes, CST Origassa, ... Scientific reports 7 (1), 40585, 2017 | 14 | 2017 |
TLR4-mediated immunomodulatory properties of the bacterial metalloprotease arazyme in preclinical tumor models FV Pereira, ACL Melo, FM de Melo, D Mourão-Sá, P Silva, R Berzaghi, ... Oncoimmunology 5 (7), e1178420, 2016 | 14 | 2016 |