Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination MMC Lam, KL Wyres, S Duchêne, RR Wick, LM Judd, YH Gan, CH Hoh, ... Nature communications 9 (1), 2703, 2018 | 242 | 2018 |
Flagella Are Virulence Determinants of Burkholderia pseudomallei KL Chua, YY Chan, YH Gan Infection and immunity 71 (4), 1622-1629, 2003 | 216 | 2003 |
Caspase‐1 dependent macrophage death induced by Burkholderia pseudomallei GW Sun, J Lu, S Pervaiz, WP Cao, YH Gan Cellular microbiology 7 (10), 1447-1458, 2005 | 167 | 2005 |
Characterization of Burkholderia pseudomallei infection and identification of novel virulence factors using a Caenorhabditis elegans host system YH Gan, KL Chua, HH Chua, B Liu, CS Hii, HL Chong, P Tan Molecular microbiology 44 (5), 1185-1197, 2002 | 146 | 2002 |
Model of Differential Susceptibility to Mucosal Burkholderia pseudomallei Infection B Liu, GC Koo, EH Yap, KL Chua, YH Gan Infection and immunity 70 (2), 504-511, 2002 | 138 | 2002 |
Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population IR Lee, JS Molton, KL Wyres, C Gorrie, J Wong, CH Hoh, J Teo, ... Scientific reports 6 (1), 29316, 2016 | 127 | 2016 |
Glutathione deficiency in type 2 diabetes impairs cytokine responses and control of intracellular bacteria KS Tan, KO Lee, KC Low, AM Gamage, Y Liu, GYG Tan, HQV Koh, ... The Journal of clinical investigation 122 (6), 2289-2300, 2012 | 123 | 2012 |
Metagenome-wide association analysis identifies microbial determinants of post-antibiotic ecological recovery in the gut KR Chng, TS Ghosh, YH Tan, T Nandi, IR Lee, AHQ Ng, C Li, ... Nature ecology & evolution 4 (9), 1256-1267, 2020 | 113 | 2020 |
Regulation of type VI secretion system during Burkholderia pseudomallei infection Y Chen, J Wong, GW Sun, Y Liu, GYG Tan, YH Gan Infection and immunity 79 (8), 3064-3073, 2011 | 100 | 2011 |
Suppression of host innate immune response by Burkholderia pseudomallei through the virulence factor TssM KS Tan, Y Chen, YC Lim, GYG Tan, Y Liu, YT Lim, P MacAry, YH Gan The Journal of Immunology 184 (9), 5160-5171, 2010 | 100 | 2010 |
The BpsIR Quorum-Sensing System of Burkholderia pseudomallei Y Song, C Xie, YM Ong, YH Gan, KL Chua Journal of bacteriology 187 (2), 785-790, 2005 | 99 | 2005 |
Interaction between Burkholderia pseudomallei and the Host Immune Response: Sleeping with the Enemy? YH Gan The Journal of infectious diseases 192 (10), 1845-1850, 2005 | 94 | 2005 |
The Condition-Dependent Transcriptional Landscape of Burkholderia pseudomallei WF Ooi, C Ong, T Nandi, JF Kreisberg, HH Chua, G Sun, Y Chen, ... PLoS genetics 9 (9), e1003795, 2013 | 90 | 2013 |
Identification of tomato plant as a novel host model for Burkholderia pseudomallei YH Lee, Y Chen, X Ouyang, YH Gan BMC microbiology 10, 1-11, 2010 | 88 | 2010 |
Flagellin contamination of recombinant heat shock protein 70 is responsible for its activity on T cells Z Ye, YH Gan Journal of Biological Chemistry 282 (7), 4479-4484, 2007 | 86 | 2007 |
Host susceptibility factors to bacterial infections in type 2 diabetes YH Gan PLoS pathogens 9 (12), e1003794, 2013 | 83 | 2013 |
Modified Virulence of Antibiotic-Induced Burkholderia pseudomallei Filaments K Chen, GW Sun, KL Chua, YH Gan Antimicrobial agents and chemotherapy 49 (3), 1002-1009, 2005 | 78 | 2005 |
A glycosylated cationic block poly (β‐peptide) reverses intrinsic antibiotic resistance in all ESKAPE gram‐negative bacteria Z Si, HW Lim, MYF Tay, Y Du, L Ruan, H Qiu, R Zamudio‐Vazquez, ... Angewandte Chemie International Edition 59 (17), 6819-6826, 2020 | 73 | 2020 |
Host cytosolic glutathione sensing by a membrane histidine kinase activates the type VI secretion system in an intracellular bacterium J Wong, Y Chen, YH Gan Cell host & microbe 18 (1), 38-48, 2015 | 60 | 2015 |
Identification of a regulatory cascade controlling Type III Secretion System 3 gene expression in Burkholderia pseudomallei GW Sun, Y Chen, Y Liu, GYG Tan, C Ong, P Tan, YH Gan Molecular microbiology 76 (3), 677-689, 2010 | 60 | 2010 |