Adenosine receptors and brain diseases: neuroprotection and neurodegeneration CV Gomes, MP Kaster, AR Tomé, PM Agostinho, RA Cunha Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (5), 1380-1399, 2011 | 494 | 2011 |
Morphological field emission-SEM study of the effect of six phosphoric acid etching agents on human dentin J Perdigão, P Lambrechts, B Van Meerbeek, ÂR Tomé, G Vanherle, ... Dental Materials 12 (4), 262-271, 1996 | 307 | 1996 |
Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress MP Kaster, NJ Machado, HB Silva, A Nunes, AP Ardais, M Santana, ... Proceedings of the National Academy of Sciences 112 (25), 7833-7838, 2015 | 306 | 2015 |
ATP as a multi-target danger signal in the brain RJ Rodrigues, AR Tomé, RA Cunha Frontiers in neuroscience 9, 148, 2015 | 256 | 2015 |
Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction N Rebola, AP Simões, PM Canas, AR Tomé, GM Andrade, CE Barry, ... Journal of neurochemistry 117 (1), 100-111, 2011 | 212 | 2011 |
Adenosine receptor antagonists including caffeine alter fetal brain development in mice CG Silva, C Métin, W Fazeli, NJ Machado, S Darmopil, PS Launay, ... Science translational medicine 5 (197), 197ra104-197ra104, 2013 | 186 | 2013 |
Control of pulsatile 5‐HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics RM Barbosa, AM Silva, AR Tomé, JA Stamford, RM Santos, LM Rosário The Journal of physiology 510 (1), 135-143, 1998 | 148 | 1998 |
Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory P Li, D Rial, PM Canas, JH Yoo, W Li, X Zhou, Y Wang, GJP van Westen, ... Molecular psychiatry 20 (11), 1339-1349, 2015 | 147 | 2015 |
Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's disease D Rial, AA Castro, N Machado, P Garção, FQ Gonçalves, HB Silva, ... PloS one 9 (12), e114216, 2014 | 126 | 2014 |
Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models W Li, HB Silva, J Real, YM Wang, D Rial, P Li, MP Payen, Y Zhou, ... Neurobiology of disease 79, 70-80, 2015 | 100 | 2015 |
Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine FQ Gonçalves, JP Lopes, HB Silva, C Lemos, AC Silva, N Gonçalves, ... Neurobiology of Disease 132, 104570, 2019 | 95 | 2019 |
Cell-specific Purinergic Receptors Coupled to Ca2+ Entry and Ca2+ Release from Internal Stores in Adrenal Chromaffin Cells: DIFFERENTIAL SENSITIVITY TO UTP AND SURAMIN (∗) E Castro, J Mateo, AR Tomé, RM Barbosa, MT Miras-Portugal, ... Journal of Biological Chemistry 270 (10), 5098-5106, 1995 | 77 | 1995 |
Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway AP Simões, JA Duarte, F Agasse, PM Canas, AR Tomé, P Agostinho, ... Journal of neuroinflammation 9, 1-16, 2012 | 63 | 2012 |
Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage R Boia, F Elvas, MH Madeira, ID Aires, AC Rodrigues-Neves, P Tralhão, ... Cell death & disease 8 (10), e3065-e3065, 2017 | 62 | 2017 |
Single-cell fura-2 microfluorometry reveals different purinoceptor subtypes coupled to Ca2+ influx and intracellular Ca2+ release in bovine adrenal chromaffin and … E Castro, AR Tomé, MT Miras-Portugal, LM Rosário Pflügers Archiv 426, 524-533, 1994 | 62 | 1994 |
Convergence of adenosine and GABA signaling for synapse stabilization during development F Gomez-Castro, S Zappettini, JC Pressey, CG Silva, M Russeau, ... Science 374 (6568), eabk2055, 2021 | 58 | 2021 |
Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate … NJ Machado, AP Simões, HB Silva, AP Ardais, MP Kaster, P Garção, ... Molecular neurobiology 54, 1552-1563, 2017 | 55 | 2017 |
Presynaptic adenosine A2A receptors dampen cannabinoid CB1 receptor‐mediated inhibition of corticostriatal glutamatergic transmission SG Ferreira, FQ Gonçalves, JM Marques, ÂR Tomé, RJ Rodrigues, ... British Journal of Pharmacology 172 (4), 1074-1086, 2015 | 54 | 2015 |
Role of adenosine in epilepsy and seizures FC Tescarollo, DM Rombo, LK DeLiberto, DE Fedele, E Alharfoush, ... Journal of caffeine and adenosine research 10 (2), 45-60, 2020 | 52 | 2020 |
Electrophysiological and immunocytochemical evidence for P2X purinergic receptors in pancreatic β cells AM Silva, RJ Rodrigues, AR Tomé, RA Cunha, S Misler, LM Rosário, ... Pancreas 36 (3), 279-283, 2008 | 52 | 2008 |