In vitro and in vivo inhibitory activity of 6-amino-2, 4, 5-trimethylpyridin-3-ols against inflammatory bowel disease S Banskota, H Kang, DG Kim, SW Park, H Jang, U Karmacharya, ... Bioorganic & medicinal chemistry letters 26 (19), 4587-4591, 2016 | 16 | 2016 |
Potent Inhibitory Effect of BJ-3105, a 6-Alkoxypyridin-3-ol Derivative, on Murine Colitis Is Mediated by Activating AMPK and Inhibiting NOX P Gurung, S Dahal, P Chaudhary, D Guragain, U Karmacharya, J Kim, ... International Journal of Molecular Sciences 21 (9), 3145, 2020 | 15 | 2020 |
Novel Pyridine Bioisostere of Cabozantinib as a Potent c-Met Kinase Inhibitor: Synthesis and Anti-Tumor Activity against Hepatocellular Carcinoma U Karmacharya, D Guragain, P Chaudhary, JG Jee, J Kim, BS Jeong International Journal of Molecular Sciences 22 (18), 9685, 2021 | 11 | 2021 |
Small Molecule Inhibitors for Unc-51-like Autophagy-Activating Kinase Targeting Autophagy in Cancer UKJW Jung Int. J. Mol. Sci. 24, 953, 2023 | 10 | 2023 |
Synthesis and activity of N-(5-hydroxy-3, 4, 6-trimethylpyridin-2-yl) acetamide analogues as anticolitis agents via dual inhibition of TNF-α-and IL-6-induced cell adhesions U Karmacharya, SC Regmi, BP Awasthi, P Chaudhary, YE Kim, IH Lee, ... Bioorganic & Medicinal Chemistry Letters 43, 128059, 2021 | 7 | 2021 |
Synthesis and anticancer evaluation of 6-azacyclonol-2, 4, 6-trimethylpyridin-3-ol derivatives: M3 muscarinic acetylcholine receptor-mediated anticancer activity of a … U Karmacharya, P Chaudhary, D Lim, S Dahal, BP Awasthi, HD Park, ... Bioorganic Chemistry 110, 104805, 2021 | 4 | 2021 |
Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens JI Brown, R Persaud, P Iliev, U Karmacharya, S Attarha, H Sahile, ... European Journal of Medicinal Chemistry 264, 115971, 2024 | 2 | 2024 |
G Protein-Coupled Estrogen Receptor-Mediated Anti-Inflammatory and Mucosal Healing Activity of a Trimethylpyridinol Analogue in Inflammatory Bowel Disease BP Awasthi, P Chaudhary, D Lim, K Yadav, IH Lee, S Banskota, ... Journal of Medicinal Chemistry, 2024 | | 2024 |