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Melissa O'Brien
Melissa O'Brien
在 dal.ca 的电子邮件经过验证
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Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis
HT Philpott, M O'Brien, JJ McDougall
Pain 158 (12), 2442-2451, 2017
3202017
Microglial pannexin-1 channel activation is a spinal determinant of joint pain
M Mousseau, NE Burma, KY Lee, H Leduc-Pessah, CHT Kwok, AR Reid, ...
Science advances 4 (8), eaas9846, 2018
902018
Age and frailty as risk factors for the development of osteoarthritis
MS O’Brien, JJ McDougall
Mechanisms of ageing and development 180, 21-28, 2019
792019
Cannabis and joints: scientific evidence for the alleviation of osteoarthritis pain by cannabinoids
M O’Brien, JJ McDougall
Current opinion in pharmacology 40, 104-109, 2018
642018
Understanding osteoarthritis pain through animal models
M O’Brien, HT Philpott, JJ McDougall
Clin Exp Rheumatol 35 (5), 47-52, 2017
462017
Targeting the Nav1. 8 ion channel engenders sex-specific responses in lysophosphatidic acid–induced joint neuropathy
MS O'Brien, HTA Philpott, JJ McDougall
Pain 160 (1), 269-278, 2019
292019
Monosodium glutamate alters the response properties of rat trigeminovascular neurons through activation of peripheral NMDA receptors
M O’Brien, BE Cairns
Neuroscience 334, 236-244, 2016
232016
Neurophysiological assessment of joint nociceptors in the rat medial meniscus transection model of post-traumatic osteoarthritis
MS O'Brien, JJ McDougall
Osteoarthritis and Cartilage 28 (9), 1255-1264, 2020
152020
Role of primary afferents in arthritis induced spinal microglial reactivity
CHT Kwok, Y Kohro, M Mousseau, MS O’Brien, JR Matyas, JJ McDougall, ...
Frontiers in Immunology 12, 626884, 2021
142021
Elevated fractalkine (CX3CL1) levels in the trigeminal ganglion mechanically sensitize temporalis muscle nociceptors
BE Cairns, M O’Brien, XD Dong, P Gazerani
Molecular Neurobiology 54, 3695-3706, 2017
142017
Analgesic potential of voltage gated sodium channel modulators for the management of pain
JJ McDougall, MS O'Brien
Current Opinion in Pharmacology 75, 102433, 2024
22024
Targeting Proteinase Activated Receptor-4 Reduces Mechanonociception During the Acute Inflammatory Phase but not the Chronic Neuropathic Phase of Osteoarthritis in Rats
MS O’Brien, JJ McDougall
Frontiers in Pharmacology 12, 756632, 2021
22021
Comparison of nociceptor properties using electrophysiology in preclinical models of osteoarthritis
MS O’Brien, JJ McDougall
Neuroscience Letters, 137950, 2024
12024
Pain processing and joint neuropathy are sex-dependent in a rat model of post-traumatic osteoarthritis
JJ McDougall, MS O'Brien
Osteoarthritis and Cartilage 28, S132, 2020
12020
Green Light Therapy Reduces Mechanical Pain In A Rat Model Of Osteoarthritis By Activating The Endocannabinoid System
MS O'Brien, C DeBow, JJ McDougall
Osteoarthritis and Cartilage 31, S377, 2023
2023
Blocking protease activated receptor-4 (PAR4) attenuates early onset osteoarthritis pain in rats
MS O'Brien, JJ McDougall
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 99 (11), S16-S16, 2021
2021
Proteinase activated receptor-4 signals pain in early but not late-stage post-traumatic osteoarthritis in rats
JJ McDougall, MS O'Brien
Osteoarthritis and Cartilage 29, S365, 2021
2021
CHARACTERISING THE NEUROPHYSIOLOGY OF POST-TRAUMATIC OSTEOARTHRITIS IN RATS AND THE INVOLVEMENT OF PROTEASE ACTIVATED RECEPTOR-4
M O'Brien
2021
Peripheral sensitization and neuropathic pain in the rat medial meniscal tear model of post-traumatic osteoarthritis
MS O'Brien, C DeBow, JJ McDougall
Osteoarthritis and Cartilage 26, S357, 2018
2018
CX3CL1-CX3CR1 signaling is involved in trigeminal nociception
P Gazerani, B Cairns, M O'Brien, XD Dong
2016
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