Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ... Nature 515 (7527), 431-435, 2014 | 2494 | 2014 |
A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury ET Chouchani, VR Pell, AM James, LM Work, K Saeb-Parsy, C Frezza, ... Cell metabolism 23 (2), 254-263, 2016 | 683 | 2016 |
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ... Nature medicine 19 (6), 753-759, 2013 | 651 | 2013 |
Succinate metabolism: a new therapeutic target for myocardial reperfusion injury VR Pell, ET Chouchani, C Frezza, MP Murphy, T Krieg Cardiovascular research 111 (2), 134-141, 2016 | 147 | 2016 |
Assessing the mitochondrial membrane potential in cells and in vivo using targeted click chemistry and mass spectrometry A Logan, VR Pell, KJ Shaffer, C Evans, NJ Stanley, EL Robb, TA Prime, ... Cell metabolism 23 (2), 379-385, 2016 | 105 | 2016 |
Moving forwards by blocking back-flow: the yin and yang of MI therapy VR Pell, ET Chouchani, MP Murphy, PS Brookes, T Krieg Circulation research 118 (5), 898-906, 2016 | 102 | 2016 |
Metabolomic profiling in acute ST‐segment–elevation myocardial infarction identifies succinate as an early marker of human ischemia–reperfusion injury M Kohlhauer, S Dawkins, ASH Costa, R Lee, T Young, VR Pell, ... Journal of the American Heart Association 7 (8), e007546, 2018 | 83 | 2018 |
Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive M Kohlhauer, VR Pell, N Burger, AM Spiroski, A Gruszczyk, JF Mulvey, ... Basic research in cardiology 114, 1-9, 2019 | 82 | 2019 |
MitoNeoD: a mitochondria-targeted superoxide probe MM Shchepinova, AG Cairns, TA Prime, A Logan, AM James, AR Hall, ... Cell chemical biology 24 (10), 1285-1298. e12, 2017 | 77 | 2017 |
Uncertainty in times of medical emergency: Knowledge gaps and structural ignorance during the Brazilian Zika crisis AH Kelly, J Lezaun, I Löwy, GC Matta, C de Oliveira Nogueira, ET Rabello Social Science & Medicine 246, 112787, 2020 | 68* | 2020 |
Using exomarkers to assess mitochondrial reactive species in vivo A Logan, HM Cochemé, PBL Pun, N Apostolova, RAJ Smith, L Larsen, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (2), 923-930, 2014 | 66 | 2014 |
Mitochondria selective S‐nitrosation by mitochondria‐targeted S‐nitrosothiol protects against post‐infarct heart failure in mouse hearts C Methner, ET Chouchani, G Buonincontri, VR Pell, SJ Sawiak, ... European journal of heart failure 16 (7), 712-717, 2014 | 63 | 2014 |
Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation VR Pell, AM Spiroski, J Mulvey, N Burger, ASH Costa, A Logan, ... Journal of Molecular and Cellular Cardiology 123, 88-91, 2018 | 47 | 2018 |
Identification and quantification of protein S-nitrosation by nitrite in the mouse heart during ischemia ET Chouchani, AM James, C Methner, VR Pell, TA Prime, BK Erickson, ... Journal of Biological Chemistry 292 (35), 14486-14495, 2017 | 47 | 2017 |
Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways JJ Maguire, RE Kuc, VR Pell, A Green, M Brown, S Kumar, T Wehrman, ... Life sciences 91 (13-14), 544-549, 2012 | 41 | 2012 |
Detection of anthracycline-induced cardiotoxicity using perfusion-corrected 99mTc sestamibi SPECT ZM Safee, F Baark, ECT Waters, M Veronese, VR Pell, JE Clark, F Mota, ... Scientific Reports 9 (1), 216, 2019 | 30 | 2019 |
Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia M Szibor, R Schreckenberg, Z Gizatullina, E Dufour, M Wiesnet, ... Journal of cellular and molecular medicine 24 (6), 3534-3548, 2020 | 16 | 2020 |
Tissue acidosis does not mediate the hypoxia selectivity of [64Cu][Cu(ATSM)] in the isolated perfused rat heart F Baark, F Shaughnessy, VR Pell, JE Clark, TR Eykyn, P Blower, ... Scientific reports 9 (1), 499, 2019 | 9 | 2019 |
A Reactivity-Based 18F-Labeled Probe for PET Imaging of Oxidative Stress in Chemotherapy-Induced Cardiotoxicity F Mota, VR Pell, N Singh, F Baark, E Waters, P Sadasivam, R Southworth, ... Molecular Pharmaceutics 19 (1), 18-25, 2021 | 2 | 2021 |
208 Cardioprotection by the mitochondria-targeted superoxide generator mitoparaquat in a murine model of acute myocardial ischaemia reperfusion injury J Mulvey, A Logan, S Arndt, V Pell, S Caldwell, R Hartley, M Murphy, ... Heart 103 (Suppl 5), A138-A139, 2017 | 2 | 2017 |