关注
Sibel Kalyoncu Uzunlar
Sibel Kalyoncu Uzunlar
Research Group Leader, Izmir Biomedicine and Genome Center
在 ibg.edu.tr 的电子邮件经过验证
标题
引用次数
引用次数
年份
Interaction prediction and classification of PDZ domains
S Kalyoncu, O Keskin, A Gursoy
BMC bioinformatics 11, 1-11, 2010
642010
Phage display derived therapeutic antibodies have enriched aliphatic content: insights for developability issues
NE Kaleli, M Karadag, S Kalyoncu
Proteins: Structure, Function, and Bioinformatics 87 (7), 607-618, 2019
322019
Protein engineering approaches for antibody fragments: directed evolution and rational design approaches
M Arslan, D Karadağ, S Kalyoncu
Turkish Journal of Biology 43 (1), 1-12, 2019
272019
Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization
JL Johnson, KC Entzminger, J Hyun, S Kalyoncu, DP Heaner, IA Morales, ...
Acta Crystallographica Section D: Biological Crystallography 71 (4), 896-906, 2015
192015
Both positional and chemical variables control in vitro proteolytic cleavage of a presenilin ortholog
SH Naing, S Kalyoncu, DM Smalley, H Kim, X Tao, JB George, AP Jonke, ...
Journal of Biological Chemistry 293 (13), 4653-4663, 2018
182018
Catalytic properties of intramembrane aspartyl protease substrate hydrolysis evaluated using a FRET peptide cleavage assay
SH Naing, KM Vukoti, JE Drury, JL Johnson, S Kalyoncu, SE Hill, ...
ACS Chemical Biology 10 (9), 2166-2174, 2015
162015
Effect of non-repetitive linker on in vitro and in vivo properties of an anti-VEGF scFv
M Arslan, M Karadag, E Onal, E Gelinci, G Cakan-Akdogan, S Kalyoncu
Scientific Reports 12 (1), 5449, 2022
132022
Roles of matrix metalloproteinases in the cornea: A special focus on macular corneal dystrophy
SG Kaya, S Inanc-Surer, G Cakan-Akdogan, G Oktay, CA Utine, ...
Medicine in Drug Discovery 11, 100095, 2021
132021
Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution
S Kalyoncu, DP Heaner Jr, Z Kurt, CM Bethel, CU Ukachukwu, ...
Nature chemical biology 12 (12), 1031-1036, 2016
122016
Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments
S Kalyoncu, J Hyun, JC Pai, JL Johnson, K Entzminger, A Jain, ...
Proteins: Structure, Function, and Bioinformatics 82 (9), 1884-1895, 2014
122014
Physicochemical determinants of antibody-protein interactions
M Karadag, M Arslan, NE Kaleli, S Kalyoncu
Advances in Protein Chemistry and Structural Biology 121, 85-114, 2020
92020
Sensitive detection of glucagon aggregation using amyloid fibril‐specific antibodies
SD Stimple, S Kalyoncu, AA Desai, JE Mogensen, LT Spang, DJ Asgreen, ...
Biotechnology and Bioengineering 116 (8), 1868-1877, 2019
82019
CENP-A nucleosome is a sensitive allosteric scaffold for DNA and chromatin factors
D Doğan, M Arslan, T Uluçay, S Kalyoncu, S Dimitrov, S Kale
Journal of molecular biology 433 (6), 166789, 2021
72021
Conformational changes in a Vernier zone region: Implications for antibody dual specificity
M Arslan, D Karadag, S Kalyoncu
Proteins: Structure, Function, and Bioinformatics 88 (11), 1447-1457, 2020
62020
Biomarkers of NRF2 signalling: Current status and future challenges
C Morgenstern, I Lastres-Becker, BC Demirdöğen, VM Costa, A Daiber, ...
Redox Biology, 103134, 2024
52024
Process development for an effective COVID-19 vaccine candidate harboring recombinant SARS-CoV-2 delta plus receptor binding domain produced by Pichia pastoris
S Kalyoncu, S Yilmaz, AZ Kuyucu, D Sayili, O Mert, H Soyturk, S Gullu, ...
Scientific reports 13 (1), 5224, 2023
52023
Directed evolution of conformation‐specific antibodies for sensitive detection of polypeptide aggregates in therapeutic drug formulations
W Lou, SD Stimple, AA Desai, EK Makowski, S Kalyoncu, JE Mogensen, ...
Biotechnology and Bioengineering 118 (2), 797-808, 2021
42021
Engineering of conserved residues near antibody heavy chain complementary determining region 3 (HCDR3) improves both affinity and stability
M Arslan, T Uluçay, S Kale, S Kalyoncu
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1871 (4), 140915, 2023
22023
Lessons from an α-Helical Membrane Enzyme: Expression, Purification, and Detergent Optimization for Biophysical and Structural Characterization
JL Johnson, S Kalyoncu, RL Lieberman
Heterologous Expression of Membrane Proteins: Methods and Protocols, 281-301, 2016
22016
Zebrafish carbohydrate sulfotransferase 6 (chst6) mutants provide a preclinical model for macular corneal dystrophy
M Basol, H Ozaktas, S Kalyoncu, CA Utine, G Cakan-Akdogan
2024
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