A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane CW Lin, LM Nocka, BL Stinger, JB DeGrandchamp, LJN Lew, S Alvarez, ... Proceedings of the National Academy of Sciences 119 (19), e2122531119, 2022 | 47 | 2022 |
Native mass spectrometry beyond ammonium acetate: effects of nonvolatile salts on protein stability and structure Z Xia, JB DeGrandchamp, ER Williams Analyst 144 (8), 2565-2573, 2019 | 43 | 2019 |
Predicting response before initiation of neoadjuvant chemotherapy in breast cancer using new methods for the analysis of dynamic contrast enhanced MRI (DCE MRI) data JB DeGrandchamp, JG Whisenant, LR Arlinghaus, VG Abramson, ... Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and …, 2016 | 7 | 2016 |
A machine-learning approach to measuring tumor pH using MRI JB DeGrandchamp, J Cárdenas-Rodríguez The University of Arizona., 2017 | 3 | 2017 |
Positive feedback in Ras activation by full-length SOS arises from autoinhibition release mechanism H Ren, AA Lee, LJN Lew, JB DeGrandchamp, JT Groves Biophysical Journal 123 (19), 3295-3303, 2024 | 2 | 2024 |
Bimodality in Ras signaling originates from processivity of the Ras activator SOS without deterministic bistability AA Lee, NH Kim, S Alvarez, H Ren, JB DeGrandchamp, LJN Lew, ... Science Advances 10 (25), eadi0707, 2024 | 1 | 2024 |
Bimodality in Ras signaling originates from processivity of the Ras activator SOS without classic kinetic bistability AA Lee, NH Kim, S Alvarez, H Ren, JB DeGrandchamp, LJN Lew, ... bioRxiv, 2023.07. 17.549263, 2023 | 1 | 2023 |
Grb2 Phosphorylation Antagonizes EGFR-driven Ras Activation by Interfering with Condensate Assembly HT Phan, CW Lin, BL Stinger, JB DeGrandchamp, LJN Lew, SJ Huang, ... bioRxiv, 2024.09. 05.611544, 2024 | | 2024 |
Positive feedback in Ras activation through modulation of SOS activation probability H Ren, A Lee, LJN Lew, JB DeGrandchamp, JT Groves Biophysical Journal 122 (3), 50a, 2023 | | 2023 |
Effect of a membrane protein condensation phase transition on reaction-diffusion kinetics LJN Lew, JB DeGrandchamp, HT Phan, CW Lin, H Ren, A Lee, JT Groves Biophysical Journal 122 (3), 442a, 2023 | | 2023 |
Regulation of EGFR phase transition through Grb2-Grb2 interactions HT Phan, CW Lin, B Stinger, JB DeGrandchamp, LJN Lew, JT Groves Biophysical Journal 122 (3), 66a, 2023 | | 2023 |