Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes H Land, LF Parada, RA Weinberg Nature 304 (5927), 596-602, 1983 | 3598 | 1983 |
A restricted cell population propagates glioblastoma growth after chemotherapy J Chen, Y Li, TS Yu, RM McKay, DK Burns, SG Kernie, LF Parada Nature 488 (7412), 522-526, 2012 | 2300 | 2012 |
The trk proto-oncogene product: a signal transducing receptor for nerve growth factor DR Kaplan, BL Hempstead, D Martin-Zanca, MV Chao, LF Parada Science 252 (5005), 554-558, 1991 | 1672 | 1991 |
Cellular oncogenes and multistep carcinogenesis H Land, LF Parada, RA Weinberg Science 222 (4625), 771-778, 1983 | 1508 | 1983 |
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor BL Hempstead, D Martin-Zanca, DR Kaplan, LF Parada, MV Chao Nature 350 (6320), 678-683, 1991 | 1494 | 1991 |
Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF DR Kaplan, D Martin-Zanca, LF Parada Nature 350 (6314), 158-160, 1991 | 1256 | 1991 |
Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene LF Parada, CJ Tabin, C Shih, RA Weinberg Nature 297 (5866), 474-478, 1982 | 1238 | 1982 |
Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation LF Parada, H Land, RA Weinberg, D Wolf, V Rotter Nature 312 (5995), 649-651, 1984 | 1038 | 1984 |
Pten regulates neuronal arborization and social interaction in mice CH Kwon, BW Luikart, CM Powell, J Zhou, SA Matheny, W Zhang, Y Li, ... Neuron 50 (3), 377-388, 2006 | 1035 | 2006 |
BDNF regulates eating behavior and locomotor activity in mice SG Kernie, DJ Liebl, LF Parada The EMBO journal 19 (6), 1290-1300, 2000 | 1000 | 2000 |
The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain R Klein, D Conway, LF Parada, M Barbacid Cell 61 (4), 647-656, 1990 | 875 | 1990 |
Smad3 mutant mice develop metastatic colorectal cancer Y Zhu, JA Richardson, LF Parada, JM Graff Cell 94 (6), 703-714, 1998 | 823 | 1998 |
Cryptorchidism in mice mutant for Insl3 S Nef, LF Parada Nature genetics 22 (3), 295-299, 1999 | 814 | 1999 |
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model SA Llaguno, J Chen, CH Kwon, EL Jackson, Y Li, DK Burns, ... Cancer cell 15 (1), 45-56, 2009 | 781 | 2009 |
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. CI Brannan, AS Perkins, KS Vogel, N Ratner, ML Nordlund, SW Reid, ... Genes & development 8 (9), 1019-1029, 1994 | 746 | 1994 |
trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development. R Klein, LF Parada, F Coulier, M Barbacid The EMBO journal 8 (12), 3701-3709, 1989 | 730 | 1989 |
Neurofibromas in NF1: Schwann cell origin and role of tumor environment Y Zhu, P Ghosh, P Charnay, DK Burns, LF Parada Science 296 (5569), 920-922, 2002 | 703 | 2002 |
TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment Y Li, BW Luikart, S Birnbaum, J Chen, CH Kwon, SG Kernie, ... Neuron 59 (3), 399-412, 2008 | 701 | 2008 |
Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain Y Zhu, MI Romero, P Ghosh, Z Ye, P Charnay, EJ Rushing, JD Marth, ... Genes & development 15 (7), 859-876, 2001 | 648 | 2001 |
Malignant glioma: lessons from genomics, mouse models, and stem cells J Chen, RM McKay, LF Parada Cell 149 (1), 36-47, 2012 | 609 | 2012 |