Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells BWM van Balkom, OG De Jong, M Smits, J Brummelman, K den Ouden, ... Blood, The Journal of the American Society of Hematology 121 (19), 3997-4006, 2013 | 565 | 2013 |
High-dimensional single cell analysis identifies stem-like cytotoxic CD8+ T cells infiltrating human tumors J Brummelman, EMC Mazza, G Alvisi, FS Colombo, A Grilli, J Mikulak, ... The Journal of experimental medicine 215 (10), 2520, 2018 | 319 | 2018 |
Single-cell sequencing of mouse heart immune infiltrate in pressure overload–driven heart failure reveals extent of immune activation E Martini, P Kunderfranco, C Peano, P Carullo, M Cremonesi, T Schorn, ... Circulation 140 (25), 2089-2107, 2019 | 256 | 2019 |
Development, application and computational analysis of high-dimensional fluorescent antibody panels for single-cell flow cytometry J Brummelman, C Haftmann, NG Nunez, G Alvisi, EMC Mazza, B Becher, ... Nature protocols 14 (7), 1946-1969, 2019 | 174 | 2019 |
IRF4 instructs effector Treg differentiation and immune suppression in human cancer G Alvisi, J Brummelman, S Puccio, EMC Mazza, EP Tomada, A Losurdo, ... The Journal of clinical investigation 130 (6), 3137-3150, 2020 | 132 | 2020 |
The single-cell phenotypic identity of human CD8+ and CD4+ T cells J Brummelman, K Pilipow, E Lugli International review of cell and molecular biology 341, 63-124, 2018 | 105 | 2018 |
Lipid-loaded tumor-associated macrophages sustain tumor growth and invasiveness in prostate cancer M Masetti, R Carriero, F Portale, G Marelli, N Morina, M Pandini, M Iovino, ... The Journal of experimental medicine 219 (2), 2022 | 79 | 2022 |
Roads to the development of improved pertussis vaccines paved by immunology J Brummelman, MM Wilk, WGH Han, CACM van Els, KHG Mills Pathogens and disease 73 (8), ftv067, 2015 | 71 | 2015 |
Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy S De Biasi, L Gibellini, D Lo Tartaro, S Puccio, C Rabacchi, EMC Mazza, ... Nature communications 12 (1), 1669, 2021 | 59 | 2021 |
Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine RHM Raeven, J Brummelman, JLA Pennings, L van der Maas, W Tilstra, ... Scientific reports 6 (1), 38240, 2016 | 54 | 2016 |
Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression RJP Bonnal, G Rossetti, E Lugli, M De Simone, P Gruarin, J Brummelman, ... Nature immunology 22 (6), 735-745, 2021 | 49 | 2021 |
Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination RHM Raeven, J Brummelman, JLA Pennings, L Van Der Maas, K Helm, ... Mucosal immunology 11 (3), 979-993, 2018 | 48 | 2018 |
Molecular Signatures of the Evolving Immune Response in Mice following a Bordetella pertussis Infection RHM Raeven, J Brummelman, JLA Pennings, OEM Nijst, B Kuipers, ... PloS one 9 (8), e104548, 2014 | 46 | 2014 |
Modulation of the CD4+ T cell response after acellular pertussis vaccination in the presence of TLR4 ligation J Brummelman, K Helm, HJ Hamstra, P van der Ley, CJP Boog, ... Vaccine 33 (12), 1483-1491, 2015 | 43 | 2015 |
Novel identified aluminum hydroxide-induced pathways prove monocyte activation and pro-inflammatory preparedness S Kooijman, J Brummelman, CACM van Els, F Marino, AJR Heck, ... Journal of proteomics 175, 144-155, 2018 | 39 | 2018 |
Background fluorescence and spreading error are major contributors of variability in high‐dimensional flow cytometry data visualization by t‐distributed stochastic neighboring … EMC Mazza, J Brummelman, G Alvisi, A Roberto, F De Paoli, V Zanon, ... Cytometry Part A 93 (8), 785-792, 2018 | 36 | 2018 |
Immunological Signatures after Bordetella pertussis Infection Demonstrate Importance of Pulmonary Innate Immune Cells RHM Raeven, J Brummelman, L van der Maas, W Tilstra, JLA Pennings, ... Plos one 11 (10), e0164027, 2016 | 26 | 2016 |
Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells J Brummelman, RE Veerman, HJ Hamstra, AJM Deuss, TJ Schuijt, ... Infection and immunity 83 (1), 227-238, 2015 | 21 | 2015 |
Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer A Losurdo, C Scirgolea, G Alvisi, J Brummelman, V Errico, L Di Tommaso, ... Communications Biology 4 (1), 1117, 2021 | 20 | 2021 |
Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4+ T cell responses through TLR4 ligation J Brummelman, RHM Raeven, K Helm, JLA Pennings, B Metz, ... Scientific reports 6 (1), 25064, 2016 | 17 | 2016 |