RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms R Fritsch, I de Krijger, K Fritsch, R George, B Reason, MS Kumar, ... Cell 153 (5), 1050-1063, 2013 | 338 | 2013 |
The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer MS Kumar, DC Hancock, M Molina-Arcas, M Steckel, P East, ... Cell 149 (3), 642-655, 2012 | 314 | 2012 |
Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance E Castellano, C Sheridan, MZ Thin, E Nye, B Spencer-Dene, ... Cancer cell 24 (5), 617-630, 2013 | 189 | 2013 |
The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer ME Diefenbacher, N Popov, SM Blake, C Schülein-Völk, E Nye, ... The Journal of clinical investigation 124 (8), 3407-3418, 2014 | 177 | 2014 |
F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor R Sancho, A Jandke, H Davis, ME Diefenbacher, I Tomlinson, A Behrens Gastroenterology 139 (3), 929-941, 2010 | 133 | 2010 |
RsfA (YbeB) proteins are conserved ribosomal silencing factors R Häuser, M Pech, J Kijek, H Yamamoto, B Titz, F Naeve, ... PLoS genetics 8 (7), e1002815, 2012 | 115 | 2012 |
Dual regulation of Fbw7 function and oncogenic transformation by Usp28 C Schülein-Völk, E Wolf, J Zhu, W Xu, L Taranets, A Hellmann, LA Jänicke, ... Cell reports 9 (3), 1099-1109, 2014 | 96 | 2014 |
The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling A Chakraborty, ME Diefenbacher, A Mylona, O Kassel, A Behrens Nature communications 6 (1), 6782, 2015 | 84 | 2015 |
Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease M Meir, N Burkard, H Ungewiß, M Diefenbacher, S Flemming, F Kannapin, ... The Journal of clinical investigation 129 (7), 2824-2840, 2019 | 81 | 2019 |
Usp28 counteracts Fbw7 in intestinal homeostasis and cancer ME Diefenbacher, A Chakraborty, SM Blake, R Mitter, N Popov, M Eilers, ... Cancer research 75 (7), 1181-1186, 2015 | 77 | 2015 |
Myosin Va cooperates with PKA RIα to mediate maintenance of the endplate in vivo IV Röder, KR Choi, M Reischl, Y Petersen, ME Diefenbacher, M Zaccolo, ... Proceedings of the National Academy of Sciences 107 (5), 2031-2036, 2010 | 75 | 2010 |
LUBAC determines chemotherapy resistance in squamous cell lung cancer EJ Ruiz, ME Diefenbacher, JK Nelson, R Sancho, F Pucci, A Chakraborty, ... Journal of Experimental Medicine 216 (2), 450-465, 2019 | 71 | 2019 |
CD24 interacts with and promotes the activity of c-src within lipid rafts in breast cancer cells, thereby increasing integrin-dependent adhesion P Baumann, W Thiele, N Cremers, S Muppala, J Krachulec, ... Cellular and Molecular Life Sciences 69, 435-448, 2012 | 70 | 2012 |
Restriction to Fos Family Members of Trip6-Dependent Coactivation and Glucocorticoid Receptor-Dependent Trans-Repression of Activator Protein-1 M Diefenbacher, S Sekula, C Heilbock, JV Maier, M Litfin, H van Dam, ... Molecular Endocrinology 22 (8), 1767-1780, 2008 | 63 | 2008 |
c-Jun localizes to the nucleus independent of its phosphorylation by and interaction with JNK and vice versa promotes nuclear accumulation of JNK I Schreck, M Al-Rawi, JM Mingot, C Scholl, ME Diefenbacher, P O’Donnell, ... Biochemical and biophysical research communications 407 (4), 735-740, 2011 | 54 | 2011 |
Maintaining protein stability of∆ Np63 via USP 28 is required by squamous cancer cells C Prieto‐Garcia, O Hartmann, M Reissland, F Braun, T Fischer, S Walz, ... EMBO molecular medicine 12 (4), e11101, 2020 | 48 | 2020 |
Dsg2 via Src-mediated transactivation shapes EGFR signaling towards cell adhesion H Ungewiß, V Rötzer, M Meir, C Fey, M Diefenbacher, N Schlegel, ... Cellular and Molecular Life Sciences 75, 4251-4268, 2018 | 42 | 2018 |
Intestinal epithelial barrier maturation by enteric glial cells is GDNF-dependent M Meir, F Kannapin, M Diefenbacher, Y Ghoreishi, C Kollmann, ... International journal of molecular sciences 22 (4), 1887, 2021 | 39 | 2021 |
Arginine methylation of the c‐Jun coactivator RACO‐1 is required for c‐Jun/AP‐1 activation CC Davies, A Chakraborty, ME Diefenbacher, M Skehel, A Behrens The EMBO journal 32 (11), 1556-1567, 2013 | 39 | 2013 |
Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance CA Cremona, R Sancho, ME Diefenbacher, A Behrens Seminars in Cancer Biology 36, 52-61, 2016 | 33 | 2016 |