Common genetic variation drives molecular heterogeneity in human iPSCs H Kilpinen, A Goncalves, A Leha, V Afzal, K Alasoo, S Ashford, S Bala, ... Nature 546 (7658), 370-375, 2017 | 606 | 2017 |
CA19-9 for detecting recurrence of pancreatic cancer A Azizian, F Rühlmann, T Krause, M Bernhardt, P Jo, A König, M Kleiß, ... Scientific Reports 10 (1), 1-10, 2020 | 156 | 2020 |
Explaining decisions of graph convolutional neural networks: patient-specific molecular subnetworks responsible for metastasis prediction in breast cancer H Chereda, A Bleckmann, K Menck, J Perera-Bel, P Stegmaier, F Auer, ... Genome medicine 13, 1-16, 2021 | 95 | 2021 |
Proteomic analysis of tear fluid reveals disease-specific patterns in patients with Parkinson's disease–A pilot study M Boerger, S Funke, A Leha, AE Roser, AK Wuestemann, F Maass, ... Parkinsonism & related disorders 63, 3-9, 2019 | 72 | 2019 |
A machine learning approach for the prediction of pulmonary hypertension A Leha, K Hellenkamp, B Unsöld, S Mushemi-Blake, AM Shah, ... PloS one 14 (10), e0224453, 2019 | 67 | 2019 |
ROCK-ALS: protocol for a randomized, placebo-controlled, double-blind phase IIa trial of safety, tolerability and efficacy of the rho kinase (ROCK) inhibitor fasudil in … P Lingor, M Weber, W Camu, T Friede, R Hilgers, A Leha, C Neuwirth, ... Frontiers in neurology 10, 293, 2019 | 63 | 2019 |
Epidermal growth factor signaling promotes sleep through a combined series and parallel neural circuit J Konietzka, M Fritz, S Spiri, R McWhirter, A Leha, S Palumbos, WS Costa, ... Current biology 30 (1), 1-16. e13, 2020 | 55 | 2020 |
Utilizing molecular network information via graph convolutional neural networks to predict metastatic event in breast cancer H Chereda, A Bleckmann, F Kramer, A Leha, T Beissbarth German Medical Data Sciences: Shaping Change–Creative Solutions for …, 2019 | 55 | 2019 |
Applications of artificial intelligence/machine learning approaches in cardiovascular medicine: A systematic review with recommendations S Friedrich, S Groß, IR König, S Engelhardt, M Bahls, J Heinz, C Huber, ... European Heart Journal-Digital Health 2 (3), 424-436, 2021 | 53 | 2021 |
Elemental fingerprint as a cerebrospinal fluid biomarker for the diagnosis of Parkinson's disease F Maass, B Michalke, A Leha, M Boerger, I Zerr, JC Koch, L Tönges, ... Journal of neurochemistry 145 (4), 342-351, 2018 | 49 | 2018 |
A high-content platform to characterise human induced pluripotent stem cell lines A Leha, N Moens, R Meleckyte, OJ Culley, MK Gervasio, M Kerz, ... Methods 96, 85-96, 2016 | 48 | 2016 |
The detection of isochromosome i (12p) in malignant germ cell tumours and tumours with somatic malignant transformation by the use of quantitative real‐time polymerase chain … A Fichtner, A Richter, S Filmar, NT Gaisa, S Schweyer, H Reis, ... Histopathology 78 (4), 593-606, 2021 | 42 | 2021 |
Selected items from the Charcot-Marie-Tooth (CMT) Neuropathy Score and secondary clinical outcome measures serve as sensitive clinical markers of disease severity in CMT1A patients M Mannil, A Solari, A Leha, AL Pelayo-Negro, J Berciano, ... Neuromuscular Disorders 24 (11), 1003-1017, 2014 | 42 | 2014 |
Comprehensive identification of genes driven by ERV9-LTRs reveals TNFRSF10B as a re-activatable mediator of testicular cancer cell death U Beyer, SK Krönung, A Leha, L Walter, M Dobbelstein Cell Death & Differentiation 23 (1), 64-75, 2016 | 41 | 2016 |
Increased alpha-synuclein tear fluid levels in patients with Parkinson’s disease F Maass, S Rikker, V Dambeck, C Warth, L Tatenhorst, I Csoti, M Schmitz, ... Scientific reports 10 (1), 8507, 2020 | 39 | 2020 |
Identifying extrinsic versus intrinsic drivers of variation in cell behavior in human iPSC lines from healthy donors A Vigilante, A Laddach, N Moens, R Meleckyte, A Leha, A Ghahramani, ... Cell reports 26 (8), 2078-2087. e3, 2019 | 39 | 2019 |
Gender affects acute organ toxicity during radiochemotherapy for rectal cancer: long-term results of the German CAO/ARO/AIO-94 phase III trial HA Wolff, LC Conradi, T Beissbarth, A Leha, W Hohenberger, S Merkel, ... Radiotherapy and Oncology 108 (1), 48-54, 2013 | 39 | 2013 |
Retrospective evaluation of extended glass‐ceramic ceramic laminate veneers after a mean observational period of 10 years S Rinke, L Bettenhäuser‐Hartung, A Leha, M Rödiger, G Schmalz, ... Journal of Esthetic and Restorative Dentistry 32 (5), 487-495, 2020 | 38 | 2020 |
Clinical evaluation of chairside‐fabricated partial crowns composed of zirconia‐reinforced lithium silicate ceramics: 3‐year results of a prospective practice‐based study S Rinke, T Pfitzenreuter, A Leha, M Roediger, D Ziebolz Journal of Esthetic and Restorative Dentistry 32 (2), 226-235, 2020 | 37 | 2020 |
Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease F Maass, B Michalke, D Willkommen, A Leha, C Schulte, L Tönges, ... Neurobiology of disease 134, 104677, 2020 | 36 | 2020 |