Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ... Cell metabolism 29 (6), 1390-1399. e6, 2019 | 346 | 2019 |
Regulatory T-cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis Y Zhang, J Lazarus, NG Steele, W Yan, HJ Lee, ZC Nwosu, CJ Halbrook, ... Cancer discovery 10 (3), 422-439, 2020 | 290 | 2020 |
Validation of the American Joint Commission on Cancer (AJCC) staging system for patients with pancreatic adenocarcinoma: a Surveillance, Epidemiology and End Results (SEER … SK Kamarajah, WR Burns, TL Frankel, CS Cho, H Nathan Annals of surgical oncology 24, 2023-2030, 2017 | 272 | 2017 |
Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer NG Steele, ES Carpenter, SB Kemp, VR Sirihorachai, S The, L Delrosario, ... Nature Cancer 1 (11), 1097-1112, 2020 | 267 | 2020 |
PRC2 epigenetically silences Th1-type chemokines to suppress effector T-cell trafficking in colon cancer N Nagarsheth, D Peng, I Kryczek, K Wu, W Li, E Zhao, L Zhao, S Wei, ... Cancer research 76 (2), 275-282, 2016 | 254 | 2016 |
A TCR targeting the HLA-A* 0201–restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer N Chinnasamy, JA Wargo, Z Yu, M Rao, TL Frankel, JP Riley, JJ Hong, ... The Journal of Immunology 186 (2), 685-696, 2011 | 214 | 2011 |
Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer NG Steele, G Biffi, SB Kemp, Y Zhang, D Drouillard, LJ Syu, Y Hao, ... Clinical Cancer Research 27 (7), 2023-2037, 2021 | 189 | 2021 |
Inhibition of ATM increases interferon signaling and sensitizes pancreatic cancer to immune checkpoint blockade therapy Q Zhang, MD Green, X Lang, J Lazarus, JD Parsels, S Wei, LA Parsels, ... Cancer research 79 (15), 3940-3951, 2019 | 178 | 2019 |
The role of tumor microenvironment in cancer immunotherapy T Frankel, MP Lanfranca, W Zou Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy, 51-64, 2017 | 154 | 2017 |
Critical evaluation of the American Joint Commission on Cancer (AJCC) staging system for patients with Hepatocellular Carcinoma (HCC): a Surveillance, Epidemiology, End Results … SK Kamarajah, TL Frankel, C Sonnenday, CS Cho, H Nathan Journal of surgical oncology 117 (4), 644-650, 2018 | 146 | 2018 |
Biological and pathological activities of interleukin-22 M Perusina Lanfranca, Y Lin, J Fang, W Zou, T Frankel Journal of molecular medicine 94, 523-534, 2016 | 144 | 2016 |
Hepatic resection for colorectal metastases TL Frankel, MI D'Angelica Journal of Surgical Oncology 109 (1), 2-7, 2014 | 120 | 2014 |
A high molecular weight melanoma-associated antigen–specific chimeric antigen receptor redirects lymphocytes to target human melanomas WR Burns, Y Zhao, TL Frankel, CS Hinrichs, Z Zheng, H Xu, SA Feldman, ... Cancer research 70 (8), 3027-3033, 2010 | 119 | 2010 |
Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase TL Frankel, WR Burns, PD Peng, Z Yu, D Chinnasamy, JA Wargo, ... The Journal of Immunology 184 (11), 5988-5998, 2010 | 118 | 2010 |
Preoperative imaging for hepatic resection of colorectal cancer metastasis TL Frankel, RKG Do, WR Jarnagin Journal of gastrointestinal oncology 3 (1), 11, 2012 | 92 | 2012 |
Spatial and phenotypic immune profiling of metastatic colon cancer J Lazarus, T Maj, JJ Smith, MP Lanfranca, A Rao, MI D’Angelica, ... JCI insight 3 (22), 2018 | 82 | 2018 |
Murine-and human-derived autologous organoid/immune cell co-cultures as pre-clinical models of pancreatic ductal adenocarcinoma L Holokai, J Chakrabarti, J Lundy, D Croagh, P Adhikary, SS Richards, ... Cancers 12 (12), 3816, 2020 | 80 | 2020 |
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages SB Kemp, NG Steele, ES Carpenter, KL Donahue, GG Bushnell, ... Life science alliance 4 (6), 2021 | 74 | 2021 |
IFNγ signaling integrity in colorectal cancer immunity and immunotherapy W Du, TL Frankel, M Green, W Zou Cellular & molecular immunology 19 (1), 23-32, 2022 | 72 | 2022 |
Coaltered Ras/B-raf and TP53 is associated with extremes of survivorship and distinct patterns of metastasis in patients with metastatic colorectal cancer J Datta, JJ Smith, WK Chatila, JC McAuliffe, C Kandoth, E Vakiani, ... Clinical Cancer Research 26 (5), 1077-1085, 2020 | 70 | 2020 |