Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins KA White, DG Ruiz, ZA Szpiech, NB Strauli, RD Hernandez, MP Jacobson, ... Science signaling 10 (495), eaam9931, 2017 | 84 | 2017 |
A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle B Goode, G Mondal, M Hyun, DG Ruiz, YH Lin, J Van Ziffle, NM Joseph, ... Nature communications 9 (1), 810, 2018 | 68 | 2018 |
Cysteine oxidation in proteins: structure, biophysics, and simulation D Garrido Ruiz, A Sandoval-Perez, AV Rangarajan, EL Gunderson, ... Biochemistry 61 (20), 2165-2176, 2022 | 53 | 2022 |
Prominent features of the amino acid mutation landscape in cancer ZA Szpiech, NB Strauli, KA White, DG Ruiz, MP Jacobson, DL Barber, ... PLoS One 12 (8), e0183273, 2017 | 47 | 2017 |
Matched targeted therapy for pediatric patients with relapsed, refractory, or high-risk leukemias: a report from the LEAP Consortium Y Pikman, SK Tasian, ML Sulis, K Stevenson, TM Blonquist, ... Cancer discovery 11 (6), 1424-1439, 2021 | 32 | 2021 |
Atp-Competitive inhibitors midostaurin and avapritinib have distinct resistance profiles in exon 17–mutant kit B Apsel Winger, WA Cortopassi, D Garrido Ruiz, L Ding, K Jang, ... Cancer research 79 (16), 4283-4292, 2019 | 30 | 2019 |
Crosstalk between RNA Pol II C-terminal domain acetylation and phosphorylation via RPRD proteins I Ali, DG Ruiz, Z Ni, JR Johnson, H Zhang, PC Li, MM Khalid, RJ Conrad, ... Molecular cell 74 (6), 1164-1174. e4, 2019 | 30 | 2019 |
Protomer alignment modulates specificity of RNA substrate recognition by Ire1 W Li, K Crotty, D Garrido Ruiz, M Voorhies, C Rivera, A Sil, RD Mullins, ... Elife 10, e67425, 2021 | 11 | 2021 |
BCR:: ABL1 kinase N-lobe mutants confer moderate to high degrees of resistance to asciminib A Leyte-Vidal, D Garrido Ruiz, RA DeFilippis, IB Leske, D Rea, S Phan, ... Blood 144 (6), 639-645, 2024 | 4 | 2024 |
The synthesis and structural requirements for measuring glucocorticoid receptor expression in vivo with (±)-11C-YJH08 PET Y Huang, N Zhao, Y Wang, C Truillet, J Wei, MFL Parker, JE Blecha, ... Journal of Nuclear Medicine 62 (5), 723-731, 2021 | 3 | 2021 |
A role for pH dynamics regulating transcription factor DNA binding selectivity KP Kisor, DG Ruiz, MP Jacobson, DL Barber bioRxiv, 2024.05. 21.595212, 2024 | 1 | 2024 |
Computational studies of pH sensing design principles in proteins D Garrido Ruiz UCSF, 2017 | | 2017 |
Computational Studies of PH Sensing Design Principles in Proteins DG Ruiz eScholarship, University of California, 2017 | | 2017 |
Retention of Somatic Mutations in Cancers by Gain in pH Sensing. KA White, ZA Szpiech, DG Ruiz, NB Strauli, MP Jacobson, R Hernandez, ... MOLECULAR BIOLOGY OF THE CELL 25, 2014 | | 2014 |