Morphological and molecular defects in human three-dimensional retinal organoid model of X-linked juvenile retinoschisis KC Huang, ML Wang, SJ Chen, JC Kuo, WJ Wang, PNN Nguyen, ... Stem Cell Reports 13 (5), 906-923, 2019 | 84 | 2019 |
Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids CM Fligor, SS Lavekar, J Harkin, PK Shields, KB VanderWall, KC Huang, ... Stem Cell Reports 16 (9), 2228-2241, 2021 | 77 | 2021 |
Retinal ganglion cells with a glaucoma OPTN (E50K) mutation exhibit neurodegenerative phenotypes when derived from three-dimensional retinal organoids KB VanderWall, KC Huang, Y Pan, SS Lavekar, CM Fligor, AR Allsop, ... Stem Cell Reports 15 (1), 52-66, 2020 | 64 | 2020 |
Differentiation of retinal organoids from human pluripotent stem cells CM Fligor, KC Huang, SS Lavekar, KB VanderWall, JS Meyer Methods in Cell Biology 159, 279-302, 2020 | 46 | 2020 |
Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN (E50K) human stem cell-derived retinal ganglion cells C Gomes, KB VanderWall, Y Pan, X Lu, SS Lavekar, KC Huang, ... Stem cell reports 17 (7), 1636-1649, 2022 | 21 | 2022 |
Enhanced mitochondrial biogenesis promotes neuroprotection in human pluripotent stem cell derived retinal ganglion cells M Surma, K Anbarasu, S Dutta, LJ Olivera Perez, KC Huang, JS Meyer, ... Communications Biology 6 (1), 218, 2023 | 11 | 2023 |
Development of a three-dimensional organoid model to explore early retinal phenotypes associated with Alzheimer’s disease SS Lavekar, J Harkin, M Hernandez, C Gomes, S Patil, KC Huang, ... Scientific Reports 13 (1), 13827, 2023 | 7 | 2023 |
Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis CH Peng, KC Huang, HE Lu, SH Syu, AA Yarmishyn, JF Lu, ... Stem Cell Research 29, 152-156, 2018 | 7 | 2018 |
Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma KC Huang, C Gomes, Y Shiga, N Belforte, KB VanderWall, SS Lavekar, ... bioRxiv, 2023 | 3 | 2023 |
Micro-PET imaging of hepatitis C virus NS3/4A protease activity using a protease-activatable retention probe CH Chuang, TL Cheng, WC Chen, YJ Huang, HE Wang, YC Lo, YC Hsieh, ... Frontiers in Microbiology 13, 896588, 2022 | 2 | 2022 |
A highly reproducible and efficient method for retinal organoid differentiation from human pluripotent stem cells J Harkin, KH Peña, C Gomes, M Hernandez, SS Lavekar, K So, K Lentsch, ... Proceedings of the National Academy of Sciences 121 (25), e2317285121, 2024 | 1 | 2024 |
Towards the optimization of human stem cell-derived RGC integration in glaucomatous non-human primate retina J Leffler, M Hernandez, KC Huang, C Gomes, A Thanos, G Cull, M Dunn, ... Investigative Ophthalmology & Visual Science 64 (8), 4696-4696, 2023 | 1 | 2023 |
Induction of astrocyte reactivity promotes neurodegeneration in human pluripotent stem cell models C Gomes, KC Huang, J Harkin, A Baker, JM Hughes, Y Pan, K Tutrow, ... Stem Cell Reports 19 (8), 1122-1136, 2024 | | 2024 |
A human induced pluripotent stem cell model of Alzheimer’s Disease-associated fractalkine receptor polymorphism to assess AD-related microglial dysfunction K Tutrow, J Harkin, M Hernandez, KCS Huang, SJ Bissel, ... Alzheimer's Association International Conference, 2024 | | 2024 |
Induction of astrocyte reactivity promotes retinal ganglion cell degeneration in human pluripotent stem cell models through complement C3 activation C Gomes, KC Huang, J Harkin, AT Baker, J Hughes, Y Pan, S Lavekar, ... Investigative Ophthalmology & Visual Science 65 (7), 4513-4513, 2024 | | 2024 |
Elucidating the influence of microglia on retinal ganglion cells in a human pluripotent stem cell model JS Meyer, J Harkin, C Gomes, S Lavekar, K Tutrow, KC Huang Investigative Ophthalmology & Visual Science 65 (7), 3256-3256, 2024 | | 2024 |
Suggested searches J Gross, ZZ Méder, CKW De Dreu, CS Burlingham, N Sendhilnathan, ... Perspective, 2024 | | 2024 |
Modulation of mTOR signaling in human induced pluripotent stem cell-derived retinal ganglion cells through the genetic regulation of RHEB A Pierce, J Harkin, KC Huang, M Hernandez, SS Lavekar, JS Meyer Investigative Ophthalmology & Visual Science 64 (8), 3178-3178, 2023 | | 2023 |
Retinal ganglion cells suffer mitophagy defects with glaucomatous Optineurin-E50K mutation K Anbarasu, M Surma, KC Huang, JS Meyer, A Das Investigative Ophthalmology & Visual Science 64 (8), 1015-1015, 2023 | | 2023 |
Reactive astrocytes contribute to retinal ganglion cell neurodegeneration in a human pluripotent stem cell model C Gomes, KC Huang, P Yangling, J Hughes, J Harkin, SS Lavekar, ... Investigative Ophthalmology & Visual Science 64 (8), 1592-1592, 2023 | | 2023 |