| Reducible poly (2-dimethylaminoethyl methacrylate): synthesis, cytotoxicity, and gene delivery activity YZ You, DS Manickam, QH Zhou, D Oupický Journal of Controlled Release 122 (3), 217-225, 2007 | 202 | 2007 |
| Dually responsive multiblock copolymers via reversible addition− fragmentation chain transfer polymerization: synthesis of temperature-and redox-responsive copolymers of poly … YZ You, QH Zhou, DS Manickam, L Wan, GZ Mao, D Oupický Macromolecules 40 (24), 8617-8624, 2007 | 126 | 2007 |
| Agile delivery of protein therapeutics to CNS X Yi, DS Manickam, A Brynskikh, AV Kabanov Journal of Controlled Release 190, 637-663, 2014 | 120 | 2014 |
| Temperature-Controlled Properties of DNA Complexes with Poly(ethylenimine)-graft-poly(N-isopropylacrylamide) HS Bisht, DS Manickam, Y You, D Oupicky Biomacromolecules 7 (4), 1169-1178, 2006 | 120 | 2006 |
| Influence of TAT-peptide polymerization on properties and transfection activity of TAT/DNA polyplexes DS Manickam, HS Bisht, L Wan, G Mao, D Oupicky Journal of Controlled Release 102 (1), 293-306, 2005 | 116 | 2005 |
| Well-defined cross-linked antioxidant nanozymes for treatment of ischemic brain injury DS Manickam, AM Brynskikh, JL Kopanic, PL Sorgen, NL Klyachko, ... Journal of controlled release 162 (3), 636-645, 2012 | 110 | 2012 |
| Multiblock reducible copolypeptides containing histidine-rich and nuclear localization sequences for gene delivery DS Manickam, D Oupický Bioconjugate chemistry 17 (6), 1395-1403, 2006 | 108 | 2006 |
| Effect of innate glutathione levels on activity of redox-responsive gene delivery vectors DS Manickam, J Li, DA Putt, QH Zhou, C Wu, LH Lash, D Oupický Journal of controlled release 141 (1), 77-84, 2010 | 106 | 2010 |
| Disassembly of layer-by-layer films of plasmid DNA and reducible TAT polypeptide J Blacklock, H Handa, DS Manickam, G Mao, A Mukhopadhyay, ... Biomaterials 28 (1), 117-124, 2007 | 99 | 2007 |
| Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins NL Klyachko, MJ Haney, Y Zhao, DS Manickam, V Mahajan, P Suresh, ... Nanomedicine 9 (9), 1403-1422, 2014 | 92 | 2014 |
| Cross-linked antioxidant nanozymes for improved delivery to CNS NL Klyachko, DS Manickam, AM Brynskikh, SV Uglanova, S Li, ... Nanomedicine: nanotechnology, biology and medicine 8 (1), 119-129, 2012 | 92 | 2012 |
| Antioxidant-based therapies for angiotensin II-associated cardiovascular diseases EG Rosenbaugh, KK Savalia, DS Manickam, MC Zimmerman American Journal of Physiology-Regulatory, Integrative and Comparative …, 2013 | 88 | 2013 |
| Nano-particle delivery of brain derived neurotrophic factor after focal cerebral ischemia reduces tissue injury and enhances behavioral recovery NM Harris, R Ritzel, NS Mancini, Y Jiang, X Yi, DS Manickam, WA Banks, ... Pharmacology Biochemistry and Behavior 150, 48-56, 2016 | 83 | 2016 |
| The attenuation of central angiotensin II-dependent pressor response and intra-neuronal signaling by intracarotid injection of nanoformulated copper/zinc superoxide dismutase EG Rosenbaugh, JW Roat, L Gao, RF Yang, DS Manickam, JX Yin, ... Biomaterials 31 (19), 5218-5226, 2010 | 82 | 2010 |
| A versatile approach to reducible vinyl polymers via oxidation of telechelic polymers prepared by reversible addition fragmentation chain transfer polymerization. YZ You, DS Manickam, QH Zhou, D Oupický Biomacromolecules 8 (6), 2038-2044, 2007 | 70 | 2007 |
| Polyplex gene delivery modulated by redox potential gradients D Soundara Manickam, D Oupický Journal of drug targeting 14 (8), 519-526, 2006 | 69 | 2006 |
| Nanoformulation of brain‐derived neurotrophic factor with target receptor‐triggered‐release in the central nervous system Y Jiang, JM Fay, CD Poon, N Vinod, Y Zhao, K Bullock, S Qin, ... Advanced functional materials 28 (6), 1703982, 2018 | 63 | 2018 |
| Targeting the blood-brain barrier for the delivery of stroke therapies A D'Souza, KM Dave, RA Stetler, DS Manickam Advanced drug delivery reviews 171, 332-351, 2021 | 53 | 2021 |
| Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides UL Rahbek, KA Howard, D Oupicky, DS Manickam, M Dong, AF Nielsen, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2008 | 52 | 2008 |
| SOD1 nanozyme with reduced toxicity and MPS accumulation Y Jiang, P Arounleut, S Rheiner, Y Bae, AV Kabanov, C Milligan, ... Journal of Controlled Release 231, 38-49, 2016 | 51 | 2016 |
