Molecular physiology of bestrophins: multifunctional membrane proteins linked to best disease and other retinopathies HC Hartzell, Z Qu, K Yu, Q Xiao, LT Chien Physiological reviews 88 (2), 639-672, 2008 | 413 | 2008 |
ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity J Gu, CW Lee, Y Fan, D Komlos, X Tang, C Sun, K Yu, HC Hartzell, ... Nature neuroscience 13 (10), 1208-1215, 2010 | 369 | 2010 |
Anoctamin/TMEM16 family members are Ca2+‐activated Cl− channels HC Hartzell, K Yu, Q Xiao, LT Chien, Z Qu The Journal of physiology 587 (10), 2127-2139, 2009 | 333 | 2009 |
Voltage-and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop Q Xiao, K Yu, P Perez-Cornejo, Y Cui, J Arreola, HC Hartzell Proceedings of the National Academy of Sciences 108 (21), 8891-8896, 2011 | 261 | 2011 |
Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology K Yu, C Duran, Z Qu, YY Cui, HC Hartzell Circulation research 110 (7), 990-999, 2012 | 198 | 2012 |
Identification of a lipid scrambling domain in ANO6/TMEM16F K Yu, JM Whitlock, K Lee, EA Ortlund, Y Yuan Cui, HC Hartzell Elife 4, e06901, 2015 | 187 | 2015 |
Characterization of the oligomeric structure of the Ca2+-activated Cl− channel Ano1/TMEM16A JT Sheridan, EN Worthington, K Yu, SE Gabriel, HC Hartzell, R Tarran Journal of Biological Chemistry 286 (2), 1381-1388, 2011 | 143 | 2011 |
MONNA, a potent and selective blocker for transmembrane protein with unknown function 16/anoctamin-1 SJ Oh, SJ Hwang, J Jung, K Yu, J Kim, JY Choi, HC Hartzell, EJ Roh, ... Molecular pharmacology 84 (5), 726-735, 2013 | 142 | 2013 |
The Ca2+‐activated Cl− channel, ANO1 (TMEM16A), is a double‐edged sword in cell proliferation and tumorigenesis Z Qu, W Yao, R Yao, X Liu, K Yu, C Hartzell Cancer medicine 3 (3), 453-461, 2014 | 138 | 2014 |
Molecular mechanism for divergent regulation of Cav1. 2 Ca2+ channels by calmodulin and Ca2+-binding protein-1 H Zhou, K Yu, KL McCoy, A Lee Journal of Biological Chemistry 280 (33), 29612-29619, 2005 | 128 | 2005 |
Bestrophins and retinopathies Q Xiao, HC Hartzell, K Yu Pflügers Archiv-European Journal of Physiology 460, 559-569, 2010 | 125 | 2010 |
The best disease-linked Cl− channel hBest1 regulates CaV1 (L-type) Ca2+ channels via src-homology-binding domains K Yu, Q Xiao, G Cui, A Lee, HC Hartzell Journal of Neuroscience 28 (22), 5660-5670, 2008 | 122 | 2008 |
Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon K Yu, R Lujan, A Marmorstein, S Gabriel, HC Hartzell The Journal of clinical investigation 120 (5), 1722-1735, 2010 | 121 | 2010 |
Suppression of Ca 2+ signaling in a mouse model of Best disease Y Zhang, JB Stanton, J Wu, K Yu, HC Hartzell, NS Peachey, ... Human molecular genetics 19 (6), 1108-1118, 2010 | 121 | 2010 |
Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase T Jiang, K Yu, HC Hartzell, E Tajkhorshid Elife 6, e28671, 2017 | 97 | 2017 |
Regulation of bestrophin Cl channels by calcium: role of the C terminus Q Xiao, A Prussia, K Yu, Y Cui, HC Hartzell The Journal of general physiology 132 (6), 681, 2008 | 95 | 2008 |
Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin K Yu, J Zhu, Z Qu, YY Cui, HC Hartzell The Journal of general physiology 143 (2), 253, 2014 | 81 | 2014 |
New VMD2 gene mutations identified in patients affected by Best vitelliform macular dystrophy D Marchant, K Yu, K Bigot, O Roche, A Germain, D Bonneau, ... Journal of medical genetics 44 (3), e70-e70, 2007 | 76 | 2007 |
The bestrophin mutation A243V, linked to adult-onset vitelliform macular dystrophy, impairs its chloride channel function K Yu, Y Cui, HC Hartzell Investigative ophthalmology & visual science 47 (11), 4956-4961, 2006 | 76 | 2006 |
Chloride channel activity of bestrophin mutants associated with mild or late-onset macular degeneration K Yu, Z Qu, Y Cui, HC Hartzell Investigative ophthalmology & visual science 48 (10), 4694-4705, 2007 | 73 | 2007 |