| Paneth cells as a site of origin for intestinal inflammation TE Adolph, MF Tomczak, L Niederreiter, HJ Ko, J Böck, E Martinez-Naves, ... Nature 503 (7475), 272-276, 2013 | 764 | 2013 |
| Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis M Tschurtschenthaler, TE Adolph, JW Ashcroft, L Niederreiter, R Bharti, ... Journal of Experimental Medicine 214 (2), 401-422, 2017 | 171 | 2017 |
| Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis A Afrazi, MF Branca, CP Sodhi, M Good, Y Yamaguchi, CE Egan, P Lu, ... Journal of Biological Chemistry 289 (14), 9584-9599, 2014 | 171 | 2014 |
| ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells L Niederreiter, TMJ Fritz, TE Adolph, AM Krismer, FA Offner, ... Journal of Experimental Medicine 210 (10), 2041-2056, 2013 | 153 | 2013 |
| C13orf31 (FAMIN) is a central regulator of immunometabolic function MZ Cader, K Boroviak, Q Zhang, G Assadi, SL Kempster, GW Sewell, ... Nature immunology 17 (9), 1046-1056, 2016 | 151 | 2016 |
| ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING K Aden, F Tran, GO Ito, R Sheibani-Tezerji, S Lipinski, JW Kuiper, ... Journal of Experimental Medicine 215 (11), 2868-2886, 2018 | 136 | 2018 |
| Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration M Tschurtschenthaler, J Wang, C Fricke, TMJ Fritz, L Niederreiter, ... Gut 63 (12), 1921-1931, 2014 | 115 | 2014 |
| Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation S Hosomi, J Grootjans, M Tschurtschenthaler, N Krupka, JD Matute, ... Journal of Experimental Medicine 214 (10), 2985-2997, 2017 | 56 | 2017 |
| PUFA-induced metabolic enteritis as a fuel for Crohn’s disease J Schwärzler, L Mayr, AV Vila, F Grabherr, L Niederreiter, M Philipp, ... Gastroenterology 162 (6), 1690-1704, 2022 | 31 | 2022 |
| Microbiota and colorectal cancer: from gut to bedside M Silva, V Brunner, M Tschurtschenthaler Frontiers in Pharmacology 12, 760280, 2021 | 30 | 2021 |
| IDO1+ Paneth cells promote immune escape of colorectal cancer S Pflügler, J Svinka, I Scharf, I Crncec, M Filipits, P Charoentong, ... Communications biology 3 (1), 252, 2020 | 28 | 2020 |
| Loss of CDX2 in colorectal cancer is associated with histopathologic subtypes and microsatellite instability but is prognostically inferior to hematoxylin–eosin-based … B Konukiewitz, M Schmitt, M Silva, J Pohl, C Lang, K Steiger, K Halfter, ... British journal of cancer 125 (12), 1632-1646, 2021 | 25 | 2021 |
| Morphology matters: a critical reappraisal of the clinical relevance of morphologic criteria from the 2019 WHO classification in a large colorectal cancer cohort comprising … M Jesinghaus, M Schmitt, C Lang, M Reiser, A Scheiter, B Konukiewitz, ... The American journal of surgical pathology 45 (7), 969-978, 2021 | 25 | 2021 |
| The selective autophagy receptor optineurin in crohn’s disease M Tschurtschenthaler, TE Adolph Frontiers in Immunology 9, 354501, 2018 | 24 | 2018 |
| XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells A Wahida, M Müller, A Hiergeist, B Popper, K Steiger, C Branca, ... Science immunology 6 (65), eabf7235, 2021 | 23 | 2021 |
| Epithelial X-box binding protein 1 coordinates tumor protein p53-driven DNA damage responses and suppression of intestinal carcinogenesis L Welz, N Kakavand, X Hang, G Laue, G Ito, MG Silva, C Plattner, ... Gastroenterology 162 (1), 223-237. e11, 2022 | 19 | 2022 |
| Non-canonical functions of SNAIL drive context-specific cancer progression MC Paul, C Schneeweis, C Falcomatà, C Shan, D Rossmeisl, S Koutsouli, ... Nature Communications 14 (1), 1201, 2023 | 18 | 2023 |
| Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis M Tschurtschenthaler, P Kachroo, FA Heinsen, TE Adolph, ... Scientific Reports 6 (1), 31640, 2016 | 18 | 2016 |
| Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer C Falcomatà, S Bärthel, A Ulrich, S Diersch, C Veltkamp, L Rad, F Boniolo, ... Cancer discovery 11 (12), 3158-3177, 2021 | 15 | 2021 |
| SMAD4 Loss Induces c-MYC–Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis LP Loevenich, M Tschurtschenthaler, M Rokavec, MG Silva, ... Cancer research 82 (24), 4604-4623, 2022 | 9 | 2022 |
