Tyrosine kinase activity and transformation potency of bcr-abl oncogene products TG Lugo, AM Pendergast, AJ Muller, ON Witte Science 247 (4946), 1079-1082, 1990 | 1768 | 1990 |
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy AJ Muller, JB DuHadaway, PS Donover, E Sutanto-Ward, GC Prendergast Nature medicine 11 (3), 312-319, 2005 | 1249 | 2005 |
Inhibition of indoleamine 2, 3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses DY Hou, AJ Muller, MD Sharma, J DuHadaway, T Banerjee, M Johnson, ... Cancer research 67 (2), 792-801, 2007 | 721 | 2007 |
Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2, 3-dioxygenase inhibitory compound D-1-methyl-tryptophan R Metz, JB DuHadaway, U Kamasani, L Laury-Kleintop, AJ Muller, ... Cancer research 67 (15), 7082-7087, 2007 | 590 | 2007 |
Indoleamine 2, 3‐dioxygenase in T‐cell tolerance and tumoral immune escape JB Katz, AJ Muller, GC Prendergast Immunological reviews 222 (1), 206-221, 2008 | 517 | 2008 |
Discovery of IDO1 inhibitors: from bench to bedside GC Prendergast, WP Malachowski, JB DuHadaway, AJ Muller Cancer research 77 (24), 6795-6811, 2017 | 515 | 2017 |
Indoleamine 2, 3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer GC Prendergast, C Smith, S Thomas, L Mandik-Nayak, L Laury-Kleintop, ... Cancer immunology, immunotherapy 63, 721-735, 2014 | 511 | 2014 |
BCR First Exon Sequences Specifically Activate the BCR/ABL Tyrosine Kinase Oncogene of Philadelphia ChromosomePositive Human Leukemias AJ Muller, JC Young, AM Pendergast, M Pondel, NR Landau, DR Littman, ... Molecular and cellular biology 11 (4), 1785-1792, 1991 | 509 | 1991 |
BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner AM Pendergast, AJ Muller, MH Havlik, Y Maru, ON Witte Cell 66 (1), 161-171, 1991 | 499 | 1991 |
The host microbiome regulates and maintains human health: a primer and perspective for non-microbiologists S Thomas, J Izard, E Walsh, K Batich, P Chongsathidkiet, G Clarke, ... Cancer research 77 (8), 1783-1812, 2017 | 375 | 2017 |
Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors AJ Muller, PA Scherle Nature Reviews Cancer 6 (8), 613-625, 2006 | 342 | 2006 |
IDO is a nodal pathogenic driver of lung cancer and metastasis development C Smith, MY Chang, KH Parker, DW Beury, JB DuHadaway, HE Flick, ... Cancer discovery 2 (8), 722-735, 2012 | 336* | 2012 |
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2, 3 dioxygenase AJ Muller, MD Sharma, PR Chandler, JB DuHadaway, ME Everhart, ... Proceedings of the National Academy of Sciences 105 (44), 17073-17078, 2008 | 288 | 2008 |
Indoleamine 2, 3-dioxygenase and its therapeutic inhibition in cancer GC Prendergast, WJ Malachowski, A Mondal, P Scherle, AJ Muller International review of cell and molecular biology 336, 175-203, 2018 | 250 | 2018 |
Structure− activity study of brassinin derivatives as indoleamine 2, 3-dioxygenase inhibitors P Gaspari, T Banerjee, WP Malachowski, AJ Muller, GC Prendergast, ... Journal of medicinal chemistry 49 (2), 684-692, 2006 | 230 | 2006 |
Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond AJ Muller, MG Manfredi, Y Zakharia, GC Prendergast Seminars in immunopathology 41, 41-48, 2019 | 224 | 2019 |
Indoleamine 2, 3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors S Kumar, WP Malachowski, JB DuHadaway, JM LaLonde, PJ Carroll, ... Journal of medicinal chemistry 51 (6), 1706-1718, 2008 | 211 | 2008 |
Indoleamine 2, 3-dioxygenase in immune suppression and cancer AJ Muller, GC Prendergast Current cancer drug targets 7 (1), 31-40, 2007 | 206 | 2007 |
A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2, 3-dioxygenase T Banerjee, JB Duhadaway, P Gaspari, E Sutanto-Ward, DH Munn, ... Oncogene 27 (20), 2851-2857, 2008 | 202 | 2008 |
Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor. AM Pendergast, AJ Muller, MH Havlik, R Clark, F McCormick, ON Witte Proceedings of the National Academy of Sciences 88 (13), 5927-5931, 1991 | 200 | 1991 |