| Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of Alzheimer's disease P Spilman, N Podlutskaya, MJ Hart, J Debnath, O Gorostiza, D Bredesen, ... PloS one 5 (4), e9979, 2010 | 1155 | 2010 |
| Mechanisms of vascular aging Z Ungvari, S Tarantini, AJ Donato, V Galvan, A Csiszar Circulation research 123 (7), 849-867, 2018 | 709 | 2018 |
| Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw, Ind) mice K Jin, V Galvan, L Xie, XO Mao, OF Gorostiza, DE Bredesen, ... Proceedings of the National Academy of Sciences 101 (36), 13363-13367, 2004 | 605 | 2004 |
| Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664 V Galvan, OF Gorostiza, S Banwait, M Ataie, AV Logvinova, S Sitaraman, ... Proceedings of the National Academy of Sciences 103 (18), 7130-7135, 2006 | 298 | 2006 |
| Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner V Galvan, B Roizman Proceedings of the National Academy of Sciences 95 (7), 3931-3936, 1998 | 295 | 1998 |
| Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease J Beauquis, P Pavía, C Pomilio, A Vinuesa, N Podlutskaya, V Galvan, ... Experimental Neurology 239, 28-37, 2013 | 245 | 2013 |
| Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer’s disease AL Lin, W Zheng, JJ Halloran, RR Burbank, SA Hussong, MJ Hart, ... Journal of Cerebral Blood Flow & Metabolism 33 (9), 1412-1421, 2013 | 224 | 2013 |
| Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice J Halloran, SA Hussong, R Burbank, N Podlutskaya, KE Fischer, ... Neuroscience 223, 102-113, 2012 | 224 | 2012 |
| Transplantation of human neural precursor cells in Matrigel scaffolding improves outcome from focal cerebral ischemia after delayed postischemic treatment in rats K Jin, XO Mao, L Xie, V Galvan, B Lai, Y Wang, O Gorostiza, X Wang, ... Journal of Cerebral Blood Flow & Metabolism 30 (3), 534-544, 2010 | 216 | 2010 |
| In vivo oxidative stress in brain of Alzheimer disease transgenic mice: requirement for methionine 35 in amyloid β-peptide of APP DA Butterfield, V Galvan, MB Lange, H Tang, RA Sowell, P Spilman, ... Free Radical Biology and Medicine 48 (1), 136-144, 2010 | 216 | 2010 |
| Glycoprotein D or J Delivered in transBlocks Apoptosis in SK-N-SH Cells Induced by a Herpes Simplex Virus 1 Mutant Lacking Intact Genes Expressing Both … G Zhou, V Galvan, G Campadelli-Fiume, B Roizman Journal of virology 74 (24), 11782-11791, 2000 | 205 | 2000 |
| Effect of rapamycin on aging and age-related diseases—past and future R Selvarani, S Mohammed, A Richardson Geroscience 43, 1135-1158, 2021 | 164 | 2021 |
| Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP MJ Saganich, BE Schroeder, V Galvan, DE Bredesen, EH Koo, ... Journal of Neuroscience 26 (52), 13428-13436, 2006 | 155 | 2006 |
| Aβ induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597–624) GM Shaked, MP Kummer, DC Lu, V Galvan, DE Bredesen, EH Koo The FASEB journal: official publication of the Federation of American …, 2006 | 155 | 2006 |
| Rapamycin and Alzheimer’s disease: time for a clinical trial? M Kaeberlein, V Galvan Science translational medicine 11 (476), eaar4289, 2019 | 154 | 2019 |
| Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer’s disease AL Lin, JB Jahrling, W Zhang, N DeRosa, V Bakshi, P Romero, V Galvan, ... Journal of Cerebral Blood Flow & Metabolism 37 (1), 217-226, 2017 | 151 | 2017 |
| Neurogenesis in the aging brain V Galvan, K Jin Clinical interventions in aging 2 (4), 605-610, 2007 | 148 | 2007 |
| Polyphosphate: a conserved modifier of amyloidogenic processes CM Cremers, D Knoefler, S Gates, N Martin, JU Dahl, J Lempart, L Xie, ... Molecular cell 63 (5), 768-780, 2016 | 143 | 2016 |
| Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain DL Vogt, D Thomas, V Galvan, DE Bredesen, BT Lamb, SW Pimplikar Neurobiology of aging 32 (9), 1725-1729, 2011 | 140 | 2011 |
| How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story A Richardson, V Galvan, AL Lin, S Oddo Experimental gerontology 68, 51-58, 2015 | 133 | 2015 |
Dale BredesenBuck Institute for Research on Aging在 buckinstitute.org 的电子邮件经过验证
