Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major S Besteiro, RAM Williams, LS Morrison, GH Coombs, JC Mottram Journal of Biological Chemistry 281 (16), 11384-11396, 2006 | 261 | 2006 |
Protein turnover and differentiation in Leishmania S Besteiro, RAM Williams, GH Coombs, JC Mottram International journal for parasitology 37 (10), 1063-1075, 2007 | 239 | 2007 |
Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana RA Williams, L Tetley, JC Mottram, GH Coombs Molecular microbiology 61 (3), 655-674, 2006 | 184 | 2006 |
Rapid sequestration of Leishmania mexicana by neutrophils contributes to the development of chronic lesion BP Hurrell, S Schuster, E Grün, M Coutaz, RA Williams, W Held, ... PLoS pathogens 11 (5), e1004929, 2015 | 126 | 2015 |
Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasite Leishmania major RAM Williams, KL Woods, L Juliano, JC Mottram, GH Coombs Autophagy 5 (2), 159-172, 2009 | 107 | 2009 |
ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major RAM Williams, TK Smith, B Cull, JC Mottram, GH Coombs PLoS pathogens 8 (5), e1002695, 2012 | 98 | 2012 |
3-Mercaptopyruvate Sulfurtransferase of LeishmaniaContains an Unusual C-terminal Extension and Is Involved in Thioredoxin and Antioxidant Metabolism RAM Williams, SM Kelly, JC Mottram, GH Coombs Journal of Biological Chemistry 278 (3), 1480-1486, 2003 | 98 | 2003 |
Plasmodium falciparum ATG8 implicated in both autophagy and apicoplast formation AM Tomlins, F Ben-Rached, RAM Williams, WR Proto, I Coppens, U Ruch, ... Autophagy 9 (10), 1540-1552, 2013 | 86 | 2013 |
Two pathways for cysteine biosynthesis in Leishmania major RAM Williams, GD Westrop, GH Coombs Biochemical Journal 420 (3), 451-462, 2009 | 80 | 2009 |
The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection M Alsaadi, JL Italia, AB Mullen, MNVR Kumar, AA Candlish, ... Journal of controlled release 160 (3), 685-691, 2012 | 66 | 2012 |
Metabolomic analyses of Leishmania reveal multiple species differences and large differences in amino acid metabolism GD Westrop, RAM Williams, L Wang, T Zhang, DG Watson, AM Silva, ... PLoS One 10 (9), e0136891, 2015 | 57 | 2015 |
Biochemical and immunological characterization of Toxoplasma gondii macrophage migration inhibitory factor C Sommerville, JM Richardson, RAM Williams, JC Mottram, CW Roberts, ... Journal of Biological Chemistry 288 (18), 12733-12741, 2013 | 54 | 2013 |
Glycosome turnover in Leishmania major is mediated by autophagy B Cull, JL Prado Godinho, JC Fernandes Rodrigues, B Frank, U Schurigt, ... Autophagy 10 (12), 2143-2157, 2014 | 51 | 2014 |
The Crystal Structure of Leishmania major 3-Mercaptopyruvate Sulfurtransferase A THREE-DOMAIN ARCHITECTURE WITH A SERINE PROTEASE-LIKE TRIAD AT THE ACTIVE SITE MS Alphey, RAM Williams, JC Mottram, GH Coombs, WN Hunter Journal of Biological Chemistry 278 (48), 48219-48227, 2003 | 51 | 2003 |
Effects of albendazole on growth of primary schoolchildren and the prevalence and intensity of soil-transmitted helminths in Sierra Leone MM Koroma, RAM Williams, RDB LaHave J Trop Pediat 42, 371-372, 1996 | 42 | 1996 |
Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishmania major RAM Williams, JC Mottram, GH Coombs Journal of Biological Chemistry 288 (5), 3678-3690, 2013 | 36 | 2013 |
Registered infant and under-five deaths in Freetown, Sierra Leone from 1987-1991 and a comparison with 1969-1979. M Hodges, RA Williams West African journal of medicine 17 (2), 95-98, 1998 | 16 | 1998 |
Comparison of albendazole and levamisole chemotherapy on prevalence and intensity of common soil-transmitted helminth infections in school children, Sierra Leone. RA Williams, MM Koroma, M Hodges West African journal of medicine 16 (3), 179-183, 1997 | 14 | 1997 |
Co-selection of antibiotic resistance in Gram-negative bacteria caused by pollution legacy in the Clyde estuary RL Tonner, T Peshkur, R Williams, I McLellan, A Hursthouse, F Henriquez, ... Strathwide 2018, 2018 | | 2018 |
Peptidases in Autophagy are Therapeutic Targets for Leishmaniasis RAM Williams Trypanosomatid Diseases: Molecular Routes to Drug Discovery, 351-364, 2013 | | 2013 |