Gating of transient receptor potential melastatin 8 (TRPM8) channels activated by cold and chemical agonists in planar lipid bilayers E Zakharian, C Cao, T Rohacs Journal of Neuroscience 30 (37), 12526-12534, 2010 | 178 | 2010 |
Inorganic polyphosphate modulates TRPM8 channels E Zakharian, B Thyagarajan, RJ French, E Pavlov, T Rohacs PloS one 4 (4), e5404, 2009 | 157 | 2009 |
A large, voltage-dependent channel, isolated from mitochondria by water-free chloroform extraction E Pavlov, E Zakharian, C Bladen, CTM Diao, C Grimbly, RN Reusch, ... Biophysical journal 88 (4), 2614-2625, 2005 | 156 | 2005 |
The TRPM8 protein is a testosterone receptor: II. Functional evidence for an ionotropic effect of testosterone on TRPM8 S Asuthkar, L Demirkhanyan, X Sun, PA Elustondo, V Krishnan, ... Journal of Biological Chemistry 290 (5), 2670-2688, 2015 | 127 | 2015 |
Oxytocin modulates nociception as an agonist of pain-sensing TRPV1 Y Nersesyan, L Demirkhanyan, D Cabezas-Bratesco, V Oakes, R Kusuda, ... Cell reports 21 (6), 1681-1691, 2017 | 124 | 2017 |
Anti-nociceptive action of peripheral mu-opioid receptors by G-beta-gamma protein-mediated inhibition of TRPM3 channels S Dembla, M Behrendt, F Mohr, C Goecke, J Sondermann, FM Schneider, ... Elife 6, e26280, 2017 | 108 | 2017 |
TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival L Mittermeier, L Demirkhanyan, B Stadlbauer, A Breit, C Recordati, ... Proceedings of the National Academy of Sciences 116 (10), 4706-4715, 2019 | 105 | 2019 |
Mitochondrial permeability transition pore induction is linked to formation of the complex of ATPase C-subunit, polyhydroxybutyrate and inorganic polyphosphate PA Elustondo, M Nichols, A Negoda, A Thirumaran, E Zakharian, ... Cell death discovery 2 (1), 1-9, 2016 | 104 | 2016 |
The TRPM8 protein is a testosterone receptor: I. Biochemical evidence for direct TRPM8-testosterone interactions S Asuthkar, PA Elustondo, L Demirkhanyan, X Sun, P Baskaran, ... Journal of Biological Chemistry 290 (5), 2659-2669, 2015 | 95 | 2015 |
Structural basis of temperature sensation by the TRP channel TRPV3 AK Singh, LL McGoldrick, L Demirkhanyan, M Leslie, E Zakharian, ... Nature structural & molecular biology 26 (11), 994-998, 2019 | 93 | 2019 |
Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel KD Nadezhdin, A Neuberger, YA Trofimov, NA Krylov, V Sinica, N Kupko, ... Nature structural & molecular biology 28 (7), 564-572, 2021 | 92 | 2021 |
TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells S Asuthkar, KK Velpula, PA Elustondo, L Demirkhanyan, E Zakharian Oncotarget 6 (19), 17221, 2015 | 82 | 2015 |
Fecal transplantation and butyrate improve neuropathic pain, modify immune cell profile, and gene expression in the PNS of obese mice RR Bonomo, TM Cook, CK Gavini, CR White, JR Jones, E Bovo, AV Zima, ... Proceedings of the National Academy of Sciences 117 (42), 26482-26493, 2020 | 76 | 2020 |
Recording of ion channel activity in planar lipid bilayer experiments E Zakharian Ion Channels: Methods and Protocols, 109-118, 2013 | 71 | 2013 |
Promiscuous activation of transient receptor potential vanilloid 1 (TRPV1) channels by negatively charged intracellular lipids: the key role of endogenous phosphoinositides in … V Lukacs, JM Rives, X Sun, E Zakharian, T Rohacs Journal of Biological Chemistry 288 (49), 35003-35013, 2013 | 70 | 2013 |
Interplay between calmodulin and phosphatidylinositol 4, 5-bisphosphate in Ca2+-induced inactivation of transient receptor potential vanilloid 6 channels C Cao, E Zakharian, I Borbiro, T Rohacs Journal of Biological Chemistry 288 (8), 5278-5290, 2013 | 57 | 2013 |
Relationship of the Escherichia coli TrkA System of Potassium Ion Uptake with the F0F1-ATPase Under Growth Conditions Without Anaerobic or Aerobic … A Trchounian, Y Ohanjanyan, K Bagramyan, V Vardanian, E Zakharyan, ... Bioscience reports 18 (3), 143-154, 1998 | 55 | 1998 |
Inorganic polyphosphate (polyP) as an activator and structural component of the mitochondrial permeability transition pore ME Solesio, PA Elustondo, E Zakharian, EV Pavlov Biochemical Society Transactions 44 (1), 7-12, 2016 | 54 | 2016 |
Polyester modification of the mammalian TRPM8 channel protein: implications for structure and function C Cao, Y Yudin, Y Bikard, W Chen, T Liu, H Li, D Jendrossek, A Cohen, ... Cell reports 4 (2), 302-315, 2013 | 53 | 2013 |
Intracellular ATP supports TRPV6 activity via lipid kinases and the generation of PtdIns (4, 5) P2 E Zakharian, C Cao, T Rohacs The FASEB Journal 25 (11), 3915, 2011 | 52 | 2011 |