| PARP1 ADP-ribosylates lysine residues of the core histone tails S Messner, M Altmeyer, H Zhao, A Pozivil, B Roschitzki, P Gehrig, ... Nucleic acids research 38 (19), 6350-6362, 2010 | 328 | 2010 |
| Multilayer membranes for glucose biosensing via layer-by-layer assembly of multiwall carbon nanotubes and glucose oxidase H Zhao, H Ju Analytical biochemistry 350 (1), 138-144, 2006 | 242 | 2006 |
| Molecular dynamics in drug design H Zhao, A Caflisch European journal of medicinal chemistry 91, 4-14, 2015 | 231 | 2015 |
| Electrodeposition of silver–DNA hybrid nanoparticles for electrochemical sensing of hydrogen peroxide and glucose S Wu, H Zhao, H Ju, C Shi, J Zhao Electrochemistry Communications 8 (8), 1197-1203, 2006 | 192 | 2006 |
| Discovery of ZAP70 inhibitors by high-throughput docking into a conformation of its kinase domain generated by molecular dynamics H Zhao, A Caflisch Bioorganic & medicinal chemistry letters 23 (20), 5721-5726, 2013 | 129 | 2013 |
| Hydrogen bonding penalty upon ligand binding H Zhao, D Huang PloS one 6 (6), e19923, 2011 | 113 | 2011 |
| Enriching screening libraries with bioactive fragment space N Zhang, H Zhao Bioorganic & Medicinal Chemistry Letters 26 (15), 3594-3597, 2016 | 110 | 2016 |
| Discovery of BRD4 bromodomain inhibitors by fragment-based high-throughput docking H Zhao, L Gartenmann, J Dong, D Spiliotopoulos, A Caflisch Bioorganic & medicinal chemistry letters 24 (11), 2493-2496, 2014 | 74 | 2014 |
| Discovery of a novel chemotype of tyrosine kinase inhibitors by fragment-based docking and molecular dynamics H Zhao, J Dong, K Lafleur, C Nevado, A Caflisch ACS medicinal chemistry letters 3 (10), 834-838, 2012 | 51 | 2012 |
| Electrochemical biosensors for DNA analysis H Ju, H Zhao Frontiers in Bioscience 10 (1), 37-46, 2005 | 44 | 2005 |
| The “gatekeeper” residue influences the mode of binding of acetyl indoles to bromodomains A Unzue, H Zhao, G Lolli, J Dong, J Zhu, M Zechner, A Dolbois, A Caflisch, ... Journal of Medicinal Chemistry 59 (7), 3087-3097, 2016 | 42 | 2016 |
| Discovery of tyrosine kinase inhibitors by docking into an inactive kinase conformation generated by molecular dynamics H Zhao, D Huang, A Caflisch ChemMedChem 7 (11), 1983-1990, 2012 | 42 | 2012 |
| Impact of PROTAC linker plasticity on the solution conformations and dissociation of the ternary complex D Weerakoon, RJ Carbajo, L De Maria, C Tyrchan, H Zhao Journal of Chemical Information and Modeling 62 (2), 340-349, 2022 | 37 | 2022 |
| Pyrrolo[3,2-b]quinoxaline Derivatives as Types I1/2 and II Eph Tyrosine Kinase Inhibitors: Structure-Based Design, Synthesis, and in Vivo Validation A Unzue, J Dong, K Lafleur, H Zhao, E Frugier, A Caflisch, C Nevado Journal of medicinal chemistry 57 (15), 6834-6844, 2014 | 37 | 2014 |
| Discovery of dual ZAP70 and Syk kinases inhibitors by docking into a rare C-helix-out conformation of Syk H Zhao, A Caflisch Bioorganic & medicinal chemistry letters 24 (6), 1523-1527, 2014 | 30 | 2014 |
| Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation A Unzue, K Lafleur, H Zhao, T Zhou, J Dong, P Kolb, J Liebl, S Zahler, ... European journal of medicinal chemistry 112, 347-366, 2016 | 26 | 2016 |
| Current kinase inhibitors cover a tiny fraction of fragment space H Zhao, A Caflisch Bioorganic & medicinal chemistry letters 25 (11), 2372-2376, 2015 | 23 | 2015 |
| Siamese recurrent neural network with a self-attention mechanism for bioactivity prediction D Fernandez-Llaneza, S Ulander, D Gogishvili, E Nittinger, H Zhao, ... ACS omega 6 (16), 11086-11094, 2021 | 21 | 2021 |
| Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases J Dong, H Zhao, T Zhou, D Spiliotopoulos, C Rajendran, XD Li, D Huang, ... ACS medicinal chemistry letters 6 (1), 79-83, 2015 | 17 | 2015 |
| Biosensor for Hepatitis B Virus DNA PCR Product and Electrochemical Study of the Interaction of Di (2, 2′‐bipyridine) osmium (III) with DNA H Zhao, H Ju Electroanalysis: An International Journal Devoted to Fundamental and …, 2004 | 14 | 2004 |
Amedeo CaflischDepartment of Biochemistry, University of Zurich在 bioc.uzh.ch 的电子邮件经过验证
