Structural basis for mismatch surveillance by CRISPR–Cas9 JPK Bravo, MS Liu, GN Hibshman, TL Dangerfield, K Jung, RS McCool, ... Nature 603 (7900), 343-347, 2022 | 181 | 2022 |
Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication JPK Bravo, TL Dangerfield, DW Taylor, KA Johnson Molecular cell 81 (7), 1548-1552. e4, 2021 | 125 | 2021 |
Remdesivir is effective in combating COVID-19 because it is a better substrate than ATP for the viral RNA-dependent RNA polymerase TL Dangerfield, NZ Huang, KA Johnson Iscience 23 (12), 2020 | 55 | 2020 |
Visible Light Mediated Bidirectional Control over Carbonic Anhydrase Activity in Cells and in Vivo Using Azobenzenesulfonamides K Aggarwal, TP Kuka, M Banik, BP Medellin, CQ Ngo, D Xie, Y Fernandes, ... Journal of the American Chemical Society 142 (34), 14522-14531, 2020 | 42 | 2020 |
Mechanisms of inhibition of viral RNA replication by nucleotide analogs KA Johnson, T Dangerfield The Enzymes 49, 39-62, 2021 | 20 | 2021 |
Conformational dynamics during high-fidelity DNA replication and translocation defined using a DNA polymerase with a fluorescent artificial amino acid TL Dangerfield, KA Johnson Journal of Biological Chemistry 296, 2021 | 19 | 2021 |
High throughput quantification of short nucleic acid samples by capillary electrophoresis with automated data processing TL Dangerfield, NZ Huang, KA Johnson Analytical biochemistry 629, 114239, 2021 | 18 | 2021 |
Optimized incorporation of an unnatural fluorescent amino acid affords measurement of conformational dynamics governing high-fidelity DNA replication TL Dangerfield, KA Johnson Journal of Biological Chemistry 295 (50), 17265-17280, 2020 | 17 | 2020 |
Kinetics of elementary steps in loop-mediated isothermal amplification (LAMP) show that strand invasion during initiation is rate-limiting TL Dangerfield, I Paik, S Bhadra, KA Johnson, AD Ellington Nucleic Acids Research 51 (1), 488-499, 2023 | 14 | 2023 |
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme S d’Oelsnitz, DJ Diaz, W Kim, DJ Acosta, TL Dangerfield, MW Schechter, ... Nature Communications 15 (1), 2084, 2024 | 13 | 2024 |
Pyrophosphate release acts as a kinetic checkpoint during high-fidelity DNA replication by the Staphylococcus aureus replicative polymerase PolC SP Fagan, P Mukherjee, WJ Jaremko, R Nelson-Rigg, RC Wilson, ... Nucleic Acids Research 49 (14), 8324-8338, 2021 | 12 | 2021 |
Substrate specificity and proposed structure of the proofreading complex of T7 DNA polymerase TL Dangerfield, S Kirmizialtin, KA Johnson Journal of Biological Chemistry 298 (3), 2022 | 10 | 2022 |
Kinetics of DNA strand transfer between polymerase and proofreading exonuclease active sites regulates error correction during high-fidelity replication TL Dangerfield, KA Johnson Journal of Biological Chemistry 299 (1), 2023 | 9 | 2023 |
Exploring the reaction mechanism of HIV reverse transcriptase with a nucleotide substrate H Wang, N Huang, T Dangerfield, KA Johnson, J Gao, R Elber The Journal of Physical Chemistry B 124 (21), 4270-4283, 2020 | 9 | 2020 |
& Taylor, DW (2024). RNA targeting and cleavage by the type III-Dv CRISPR effector complex EA Schwartz, JP Bravo, M Ahsan, LA Macias, CL McCafferty, ... Nature Communications 15 (1), 3324, 0 | 9 | |
Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9 GN Hibshman, JPK Bravo, MM Hooper, TL Dangerfield, H Zhang, ... Nature Communications 15 (1), 3663, 2024 | 8 | 2024 |
Conformational dynamics during misincorporation and mismatch extension defined using a DNA polymerase with a fluorescent artificial amino acid TL Dangerfield, S Kirmizialtin, KA Johnson Journal of Biological Chemistry 298 (1), 2022 | 7 | 2022 |
Expression and purification of tag-free SARS-CoV-2 RNA-dependent RNA polymerase in Escherichia coli TL Dangerfield, NZ Huang, KA Johnson STAR protocols 2 (1), 100357, 2021 | 7 | 2021 |
RNA targeting and cleavage by the type III-Dv CRISPR effector complex EA Schwartz, JPK Bravo, M Ahsan, LA Macias, CL McCafferty, ... Nature communications 15 (1), 3324, 2024 | 6* | 2024 |
Publisher Correction: Structural basis for mismatch surveillance by CRISPR–Cas9 JPK Bravo, MS Liu, GN Hibshman, TL Dangerfield, K Jung, RS McCool, ... Nature 604 (7904), E10, 2022 | 4 | 2022 |