Monoclonal TCR-redirected tumor cell killing N Liddy, G Bossi, KJ Adams, A Lissina, TM Mahon, NJ Hassan, J Gavarret, ... Nature medicine 18 (6), 980-987, 2012 | 1023 | 2012 |
Induction of complete and molecular remissions in acute myeloid leukemia by Wilms’ tumor 1 antigen-targeted dendritic cell vaccination VF Van Tendeloo, A Van de Velde, A Van Driessche, N Cools, S Anguille, ... Proceedings of the National Academy of Sciences 107 (31), 13824-13829, 2010 | 467 | 2010 |
VDJdb: a curated database of T-cell receptor sequences with known antigen specificity M Shugay, DV Bagaev, IV Zvyagin, RM Vroomans, JC Crawford, G Dolton, ... Nucleic acids research 46 (D1), D419-D427, 2018 | 434 | 2018 |
Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance MS Davey, CR Willcox, SP Joyce, K Ladell, SA Kasatskaya, JE McLaren, ... Nature communications 8 (1), 14760, 2017 | 259 | 2017 |
MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage MC Gold, JE McLaren, JA Reistetter, S Smyk-Pearson, K Ladell, ... Journal of Experimental Medicine 211 (8), 1601-1610, 2014 | 214 | 2014 |
Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia S Anguille, AL Van de Velde, EL Smits, VF Van Tendeloo, G Juliusson, ... Blood, The Journal of the American Society of Hematology 130 (15), 1713-1721, 2017 | 208 | 2017 |
Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors S Culina, AI Lalanne, G Afonso, K Cerosaletti, S Pinto, G Sebastiani, ... Science immunology 3 (20), eaao4013, 2018 | 194 | 2018 |
Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans G Galletti, G De Simone, EMC Mazza, S Puccio, C Mezzanotte, TM Bi, ... Nature immunology 21 (12), 1552-1562, 2020 | 191 | 2020 |
A recombinant modified vaccinia ankara vaccine encoding Epstein–Barr virus (EBV) target antigens: a phase I trial in UK patients with EBV-positive cancer GS Taylor, H Jia, K Harrington, LW Lee, J Turner, K Ladell, DA Price, ... Clinical Cancer Research 20 (19), 5009-5022, 2014 | 188 | 2014 |
TCR β-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV V Venturi, HY Chin, TE Asher, K Ladell, P Scheinberg, E Bornstein, ... The Journal of Immunology 181 (11), 7853-7862, 2008 | 188 | 2008 |
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers A Lissina, K Ladell, A Skowera, M Clement, E Edwards, R Seggewiss, ... Journal of immunological methods 340 (1), 11-24, 2009 | 182 | 2009 |
A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells K Ladell, M Hashimoto, MC Iglesias, PG Wilmann, JE McLaren, S Gras, ... Immunity 38 (3), 425-436, 2013 | 173 | 2013 |
Role of naive-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation A Roberto, L Castagna, V Zanon, S Bramanti, R Crocchiolo, JE McLaren, ... Blood, The Journal of the American Society of Hematology 125 (18), 2855-2864, 2015 | 162 | 2015 |
Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition DK Cole, ESJ Edwards, KK Wynn, M Clement, JJ Miles, K Ladell, ... The Journal of Immunology 185 (4), 2600-2610, 2010 | 160 | 2010 |
Highly prevalent colorectal cancer-infiltrating LAP+ Foxp3− T cells exhibit more potent immunosuppressive activity than Foxp3+ regulatory T cells M Scurr, K Ladell, M Besneux, A Christian, T Hockey, K Smart, ... Mucosal immunology 7 (2), 428-439, 2014 | 157 | 2014 |
Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease T Mayassi, K Ladell, H Gudjonson, JE McLaren, DG Shaw, MT Tran, ... Cell 176 (5), 967-981. e19, 2019 | 154 | 2019 |
TCR binding affinity governs the functional profile of cancer-specific CD8 T cells MP Tan, AB Gerry, JE Brewer, L Melchiori, JS Bridgeman, AD Bennett Clin Exp Immunol 180, 255-270, 2014 | 152* | 2014 |
Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors JP Hindley, C Ferreira, E Jones, SN Lauder, K Ladell, KK Wynn, GJ Betts, ... Cancer research 71 (3), 736-746, 2011 | 146 | 2011 |
AT cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+ M1 in adults aged over 50 years RD Antrobus, PJ Lillie, TK Berthoud, AJ Spencer, JE McLaren, K Ladell, ... PloS one 7 (10), e48322, 2012 | 144 | 2012 |
β-Cell–specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure A Skowera, K Ladell, JE McLaren, G Dolton, KK Matthews, E Gostick, ... Diabetes 64 (3), 916-925, 2015 | 136 | 2015 |