Disruption of DNA-methylation-dependent long gene repression in Rett syndrome HW Gabel, B Kinde, H Stroud, CS Gilbert, DA Harmin, NR Kastan, ... Nature 522 (7554), 89-93, 2015 | 552 | 2015 |
Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor MJ Lyst, R Ekiert, DH Ebert, C Merusi, J Nowak, J Selfridge, J Guy, ... Nature neuroscience 16 (7), 898-902, 2013 | 399 | 2013 |
Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR DH Ebert, HW Gabel, ND Robinson, NR Kastan, LS Hu, S Cohen, ... Nature 499 (7458), 341-345, 2013 | 248 | 2013 |
Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues N Kastan, K Gnedeva, T Alisch, AA Petelski, DJ Huggins, J Chiaravalli, ... Nature communications 12 (1), 3100, 2021 | 102 | 2021 |
Thermal excitation of the mechanotransduction apparatus of hair cells JB Azimzadeh, BA Fabella, NR Kastan, AJ Hudspeth Neuron 97 (3), 586-595. e4, 2018 | 16 | 2018 |
Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs NR Kastan, S Oak, R Liang, L Baxt, RW Myers, J Ginn, N Liverton, ... Proceedings of the National Academy of Sciences 119 (28), e2206113119, 2022 | 15 | 2022 |
Role of YAP in early ectodermal specification and a Huntington's Disease model of human neurulation FM Piccolo, NR Kastan, T Haremaki, Q Tian, TL Laundos, R De Santis, ... elife 11, e73075, 2022 | 10 | 2022 |
Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischemic injury A Shakked, Z Petrover, A Aharonov, M Ghiringhelli, KB Umansky, D Kain, ... Nature cardiovascular research 2 (4), 383-398, 2023 | 4 | 2023 |
Small-molecule inhibition of Lats kinases promotes Yap-dependent proliferation in postmitotic mammalian tissues N Kastan, K Gnedeva, T Alisch, AA Petelski, DJ Huggins, J Chiaravalli, ... bioRxiv, 2020.02. 11.944157, 2020 | 3 | 2020 |
PYRROLO [2, 3-b] PYRIDINE-3-CARBOXAMIDE COMPOSITIONS AND METHODS FOR AMELIORATING HEARING LOSS K Gnedeva, AJ HUDSPETH, N Kastan, R Liang, PT Meinke, DJ Huggins, ... US Patent App. 17/760,143, 2023 | | 2023 |
Small-Molecule Activation of YAP for Inner-Ear Regeneration and Beyond N Kastan | | 2020 |