4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer N Nagy, HF Kuipers, AR Frymoyer, HD Ishak, JB Bollyky, TN Wight, ... Frontiers in immunology 6, 123, 2015 | 303 | 2015 |
Inhibition of hyaluronan synthesis accelerates murine atherosclerosis: novel insights into the role of hyaluronan synthesis N Nagy, T Freudenberger, A Melchior-Becker, K Röck, M Ter Braak, ... Circulation 122 (22), 2313-2322, 2010 | 204 | 2010 |
Hyaluronan and hyaluronan-binding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis M Bogdani, PY Johnson, S Potter-Perigo, N Nagy, AJ Day, PL Bollyky, ... Diabetes 63 (8), 2727-2743, 2014 | 120 | 2014 |
Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis N Nagy, G Kaber, PY Johnson, JA Gebe, A Preisinger, BA Falk, ... The Journal of clinical investigation 125 (10), 3928-3940, 2015 | 93 | 2015 |
Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization HF Kuipers, M Rieck, I Gurevich, N Nagy, MJ Butte, RS Negrin, TN Wight, ... Proceedings of the National Academy of Sciences 113 (5), 1339-1344, 2016 | 84 | 2016 |
Hydrogel-based delivery of Il-10 improves treatment of bleomycin-induced lung fibrosis in mice EA Shamskhou, MJ Kratochvil, ME Orcholski, N Nagy, G Kaber, E Steen, ... Biomaterials 203, 52-62, 2019 | 81 | 2019 |
Hyaluronan in immune dysregulation and autoimmune diseases N Nagy, HF Kuipers, PL Marshall, E Wang, G Kaber, PL Bollyky Matrix Biology 78, 292-313, 2019 | 69 | 2019 |
Inhibitory role of the small leucine-rich proteoglycan biglycan in bladder cancer C Niedworok, K Röck, I Kretschmer, T Freudenberger, N Nagy, T Szarvas, ... PloS one 8 (11), e80084, 2013 | 62 | 2013 |
Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E-Deficient Mice: Implications for Inflammation and Atherosclerosis M Grandoch, C Kohlmorgen, A Melchior-Becker, K Feldmann, S Homann, ... Arteriosclerosis, thrombosis, and vascular biology 36 (5), e41-e50, 2016 | 57 | 2016 |
Hyaluronan synthase 3 promotes plaque inflammation and atheroprogression S Homann, M Grandoch, LS Kiene, Y Podsvyadek, K Feldmann, ... Matrix Biology 66, 67-80, 2018 | 51 | 2018 |
The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice HF Kuipers, N Nagy, SM Ruppert, VG Sunkari, PL Marshall, JA Gebe, ... Clinical & Experimental Immunology 185 (3), 372-381, 2016 | 50 | 2016 |
Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis AK Meinecke, N Nagy, GDA Lago, S Kirmse, R Klose, K Schrödter, ... Blood, The Journal of the American Society of Hematology 119 (24), 5931-5942, 2012 | 50 | 2012 |
Hyaluronan content governs tissue stiffness in pancreatic islet inflammation N Nagy, A De La Zerda, G Kaber, PY Johnson, KH Hu, MJ Kratochvil, ... Journal of Biological Chemistry 293 (2), 567-578, 2018 | 46 | 2018 |
Deficiency in lymphotoxin β receptor protects from atherosclerosis in apoE-deficient mice M Grandoch, K Feldmann, JR Göthert, LS Dick, S Homann, C Klatt, ... Circulation research 116 (8), e57-e68, 2015 | 43 | 2015 |
4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition N Nagy, I Gurevich, HF Kuipers, SM Ruppert, PL Marshall, BJ Xie, W Sun, ... Journal of Biological Chemistry 294 (19), 7864-7877, 2019 | 39 | 2019 |
Hyaluronan: a mediator of islet dysfunction and destruction in diabetes? RL Hull, M Bogdani, N Nagy, PY Johnson, TN Wight Journal of Histochemistry & Cytochemistry 63 (8), 592-603, 2015 | 39 | 2015 |
Hyaluronan levels are increased systemically in human type 2 but not type 1 diabetes independently of glycemic control N Nagy, VG Sunkari, G Kaber, S Hasbun, DN Lam, C Speake, S Sanda, ... Matrix Biology 80, 46-58, 2019 | 38 | 2019 |
Impact of eNOS-dependent oxidative stress on endothelial function and neointima formation T Suvorava, N Nagy, S Pick, O Lieven, U Rüther, VTV Dao, JW Fischer, ... Antioxidants & redox signaling 23 (9), 711-723, 2015 | 34 | 2015 |
Long-term treatment with the AT1-receptor antagonist telmisartan inhibits biglycan accumulation in murine atherosclerosis N Nagy, A Melchior-Becker, JW Fischer Basic research in cardiology 105 (1), 29-38, 2010 | 32 | 2010 |
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist CR Glassman, L Su, SS Majri-Morrison, H Winkelmann, F Mo, P Li, ... Elife 10, e65777, 2021 | 25 | 2021 |