| Histone γH2AX and poly (ADP-ribose) as clinical pharmacodynamic biomarkers CE Redon, AJ Nakamura, YW Zhang, J Ji, WM Bonner, RJ Kinders, ... Clinical cancer research 16 (18), 4532-4542, 2010 | 304 | 2010 |
| Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I–DNA complexes M Regairaz, YW Zhang, H Fu, KK Agama, N Tata, S Agrawal, MI Aladjem, ... The Journal of cell biology 195 (5), 739, 2011 | 185 | 2011 |
| Poly (ADP-ribose) polymerase and XPF–ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells YW Zhang, M Regairaz, JA Seiler, KK Agama, JH Doroshow, Y Pommier Nucleic acids research 39 (9), 3607-3620, 2011 | 183 | 2011 |
| Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response YW Zhang, TL Jones, SE Martin, NJ Caplen, Y Pommier Journal of Biological Chemistry 284 (27), 18085-18095, 2009 | 163 | 2009 |
| Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses ZH Miao, A Player, U Shankavaram, YH Wang, DB Zimonjic, PL Lorenzi, ... Cancer research 67 (18), 8752-8761, 2007 | 113 | 2007 |
| Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria H Zhang, YW Zhang, T Yasukawa, I Dalla Rosa, S Khiati, Y Pommier Nucleic acids research 42 (11), 7259-7267, 2014 | 87 | 2014 |
| Anti-angiogenic effects of Shiraiachrome A, a compound isolated from a Chinese folk medicine used to treat rheumatoid arthritis Y Tong, X Zhang, W Zhao, Y Zhang, J Lang, Y Shi, W Tan, M Li, Y Zhang, ... European journal of pharmacology 494 (2-3), 101-109, 2004 | 62 | 2004 |
| Schedule-dependent synergy of histone deacetylase inhibitors with DNA damaging agents in small cell lung cancer VL Luchenko, CD Salcido, Y Zhang, K Agama, E Komlodi-Pasztor, ... Cell cycle 10 (18), 3119-3128, 2011 | 54 | 2011 |
| RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors S E Martin, ZH Wu, K Gehlhaus, T L Jones, YW Zhang, R Guha, ... Current cancer drug targets 11 (8), 976-986, 2011 | 49 | 2011 |
| DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment S Solier, Y W Zhang, A Ballestrero, Y Pommier, G Zoppoli Current cancer drug targets 12 (4), 356-371, 2012 | 45 | 2012 |
| hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells Y Shen, YW Zhang, ZX Zhang, ZH Miao, J Ding Cancer biology & therapy 7 (2), 228-236, 2008 | 44 | 2008 |
| Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation YW Zhang, RE Nasto, R Varghese, SA Jablonski, IG Serebriiskii, ... Oncogene 35 (13), 1643-1656, 2016 | 33 | 2016 |
| Lasonolide A, a potent and reversible inducer of chromosome condensation YW Zhang, AK Ghosh, Y Pommier Cell Cycle 11 (23), 4424-4435, 2012 | 26 | 2012 |
| The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine YW Zhang, ZX Zhang, ZH Miao, J Ding Molecular Pharmacology 73 (3), 824-832, 2008 | 22 | 2008 |
| Alternative splicing of human telomerase reverse transcriptase may not be involved in telomerase regulation during all-trans-retinoic acid-induced HL-60 cell differentiation WJ Liu, YW Zhang, ZX Zhang, J Ding Journal of pharmacological sciences 96 (2), 106-114, 2004 | 20 | 2004 |
| Activation of RAF1 (c-RAF) by the marine alkaloid lasonolide A induces rapid premature chromosome condensation R Jossé, YW Zhang, V Giroux, AK Ghosh, J Luo, Y Pommier Marine Drugs 13 (6), 3625-3639, 2015 | 19 | 2015 |
| Telomerase inhibition is a specific early event in salvicine-treated human lung adenocarcinoma A549 cells WJ Liu, YW Zhang, Y Shen, JF Jiang, ZH Miao, J Ding Biochemical and biophysical research communications 323 (2), 660-667, 2004 | 16 | 2004 |
| Induction of glutathione-dependent DNA double-strand breaks by the novel anticancer drug brostallicin J Guirouilh-Barbat, YW Zhang, Y Pommier Molecular cancer therapeutics 8 (7), 1985-1994, 2009 | 11 | 2009 |
| The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine (vol 73, pg 824, 2008) YW Zhang, ZW Zhang, ZH Miao, J Ding MOLECULAR PHARMACOLOGY 73 (5), 1587-1587, 2008 | 1 | 2008 |
| Lasonolide compounds as reagents for inducing premature chromosome condensation and methods for treating disorders Y Pommier, Y Zhang, AK Ghosh US Patent 8,278,100, 2012 | | 2012 |
