Recurrent SETBP1 mutations in atypical chronic myeloid leukemia R Piazza, S Valletta, N Winkelmann, S Redaelli, R Spinelli, A Pirola, ... Nature genetics 45 (1), 18-24, 2013 | 421 | 2013 |
Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing S Valletta, A Thomas, Y Meng, X Ren, R Drissen, H Sengül, C Di Genua, ... Nature communications 11 (1), 4075, 2020 | 90 | 2020 |
Application of CRISPR/Cas9 genome editing to the study and treatment of disease A Pellagatti, H Dolatshad, S Valletta, J Boultwood Archives of toxicology 89, 1023-1034, 2015 | 84 | 2015 |
ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts S Valletta, H Dolatshad, M Bartenstein, BH Yip, E Bello, S Gordon, Y Yu, ... Oncotarget 6 (42), 44061, 2015 | 75 | 2015 |
Targeted resequencing analysis of 31 genes commonly mutated in myeloid disorders in serial samples from myelodysplastic syndrome patients showing disease progression A Pellagatti, S Roy, C Di Genua, A Burns, K McGraw, S Valletta, ... Leukemia 30 (1), 248-250, 2016 | 63 | 2016 |
FusionAnalyser: a new graphical, event-driven tool for fusion rearrangements discovery R Piazza, A Pirola, R Spinelli, S Valletta, S Redaelli, V Magistroni, ... Nucleic acids research 40 (16), e123-e123, 2012 | 41 | 2012 |
CEQer: a graphical tool for copy number and allelic imbalance detection from whole-exome sequencing data R Piazza, V Magistroni, A Pirola, S Redaelli, R Spinelli, S Redaelli, ... PloS one 8 (10), e74825, 2013 | 27 | 2013 |
Application of genome editing technologies to the study and treatment of hematological disease A Pellagatti, H Dolatshad, BH Yip, S Valletta, J Boultwood Advances in biological regulation 60, 122-134, 2016 | 26 | 2016 |
C/EBPα and GATA-2 mutations induce bilineage acute erythroid leukemia through transformation of a neomorphic neutrophil-erythroid progenitor C Di Genua, S Valletta, M Buono, B Stoilova, C Sweeney, ... Cancer Cell 37 (5), 690-704. e8, 2020 | 24 | 2020 |
Identification of novel point mutations in splicing sites integrating whole‐exome and RNA‐seq data in myeloproliferative diseases R Spinelli, A Pirola, S Redaelli, N Sharma, H Raman, S Valletta, ... Molecular genetics & genomic medicine 1 (4), 246-259, 2013 | 21 | 2013 |
Epigenetic programming defines haematopoietic stem cell fate restriction Y Meng, J Carrelha, R Drissen, X Ren, B Zhang, A Gambardella, ... Nature Cell Biology 25 (6), 812-822, 2023 | 13 | 2023 |
SETBP1 and CSF3R Mutations In Atypical Chronic Myeloid Leukemia R Piazza, S Redaelli, S Valletta, A Pirola, R Spinelli, V Magistroni, ... Blood 122 (21), 2598, 2013 | 5 | 2013 |
Bi-Allelic CEBPA Mutation Combined with a Novel GATA2 Mutation Develops an Acute Erythroid Leukemia Through a Bi-Potent Leukemic Initiating Population C Di Genua, S Valletta, R Drissen, M Buono, S Thongjuea, C Nerlov Experimental Hematology 64, S61, 2018 | 1 | 2018 |
Recurrent KIT D816V mutation in atypical chronic myeloid leukemia R Piazza, S Redaelli, A Pirola, S Valletta, V Magistroni, N Cross, D Rea, ... HAEMATOLOGICA 99, 509-509, 2014 | 1 | 2014 |
CML patients present additional mutations in cancer related genes when tested at diagnosis C Gambacorti-Passerini, S Valletta, A Stasia, A Leeksma, N Sharma, ... Blood 118 (21), 2739, 2011 | 1 | 2011 |
S128: AML CONDITIONING OF THE BONE MARROW MICROENVIRONMENT THROUGH CCR1 LIGAND UP-REGULATION PROMOTES AML STEM CELL PROPAGATION AND IS MIMICKED BY AGEING X Ren, A Thomas, Y Meng, C Nerlov, S Valletta HemaSphere 7, e8112156, 2023 | | 2023 |
3016–CCR1 AS A POTENTIAL THERAPEUTIC TARGET FOR AML IN THE ELDERLY X Ren, A Thomas, Y Meng, S Valletta, C Nerlov Experimental Hematology 111, S52, 2022 | | 2022 |
3035–AGEING MIMICS LEUKEMIC ADAPTATION OF BONE MARROW STROMAL CELLS AND PROMOTES ACUTE MYELOID LEUKEMIA INITIATION S Valletta, A Thomas, X Ren, C Nerlov Experimental Hematology 100, S60, 2021 | | 2021 |
CORRECTION OF MUTATIONS OF THE EPIGENETIC MODIFIER ASXL1 IN MYELOID LEUKEMIA CELLS BY CRISPR/CAS9 GENOME EDITING S Valletta, H Dolatshad, E Bello, BH Yip, M Bartenstein, S Gordon, J Shaw, ... HAEMATOLOGICA 100, 169-169, 2015 | | 2015 |
Targeted resequencing analysis of 31 genes commonly mutated in myeloid disorders in serial samples from myelodysplastic syndrome patients showing disease progression. S Valletta Leukemia, 2015 | | 2015 |