| Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons? AM Tukker, MW de Groot, FMJ Wijnolts, EEJ Kasteel, L Hondebrink, ... ALTEX-Alternatives to animal experimentation 33 (3), 261-271, 2016 | 82 | 2016 |
| Comparison of the acute inhibitory effects of Tetrodotoxin (TTX) in rat and human neuronal networks for risk assessment purposes EEJ Kasteel, RHS Westerink Toxicology letters 270, 12-16, 2017 | 66 | 2017 |
| Neuropharmacological characterization of the new psychoactive substance methoxetamine L Hondebrink, EEJ Kasteel, AM Tukker, FMJ Wijnolts, AHA Verboven, ... Neuropharmacology 123, 1-9, 2017 | 44 | 2017 |
| Human variability in isoform-specific UDP-glucuronosyltransferases: markers of acute and chronic exposure, polymorphisms and uncertainty factors EEJ Kasteel, K Darney, NI Kramer, J Dorne, LS Lautz Archives of toxicology 94, 2637-2661, 2020 | 41 | 2020 |
| Acetylcholinesterase inhibition in electric eel and human donor blood: an in vitro approach to investigate interspecies differences and human variability in toxicodynamics EEJ Kasteel, SM Nijmeijer, K Darney, LS Lautz, JLCM Dorne, NI Kramer, ... Archives of Toxicology 94 (12), 4055-4065, 2020 | 28 | 2020 |
| Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment K Darney, EEJ Kasteel, FM Buratti, L Turco, S Vichi, C Béchaux, ... Environment international 138, 105609, 2020 | 24 | 2020 |
| Modelling human variability in toxicokinetic and toxicodynamic processes using Bayesian meta‐analysis, physiologically‐based modelling and in vitro systems E Testai, C Bechaux, FM Buratti, K Darney, E Di Consiglio, EEJ Kasteel, ... EFSA Supporting Publications 18 (4), 6504E, 2021 | 22 | 2021 |
| Inter-ethnic differences in CYP3A4 metabolism: a Bayesian meta-analysis for the refinement of uncertainty factors in chemical risk assessment K Darney, E Testai, FM Buratti, E Di Consiglio, EEJ Kasteel, N Kramer, ... Computational Toxicology 12, 100092, 2019 | 17 | 2019 |
| Refining in vitro and in silico neurotoxicity approaches by accounting for interspecies and interindividual differences in toxicodynamics EEJ Kasteel, RHS Westerink Expert Opinion on Drug Metabolism & Toxicology 17 (8), 1007-1017, 2021 | 11 | 2021 |
| Application of in vitro data in physiologically-based kinetic models for quantitative in vitro-in vivo extrapolation: A case-study for baclofen EEJ Kasteel, LS Lautz, M Culot, NI Kramer, A Zwartsen Toxicology in Vitro 76, 105223, 2021 | 10 | 2021 |
| Reconnecting exposure, toxicokinetics and toxicity in food safety: OpenFoodTox and TKplate for human health, animal health and ecological risk assessment JL Dorne, B Amzal, N Quignot, W Wiecek, C Bechaux, K Darney, A Grech, ... 54. Congress of the European Societies of Toxicology (EUROTOX 2018) 295 …, 2018 | 4 | 2018 |
| Next Generation Risk Assessment of Chemicals: In vitro and in silico approaches to work towards enough precision to make a decision EEJ Kasteel Utrecht University, 2021 | | 2021 |
| A quantitative adverse outcome pathway for hepatic steatosis combined with in vitro kinetics using HepaRG cells E Kasteel, S Nijmeijer, NI Kramer TOXICOLOGY LETTERS 314, S168-S169, 2019 | | 2019 |
| Hierarchical Bayesian meta-analysis of human variability in PON1 metabolism for the refinement of uncertainty factors in chemical risk assessment L Lautz, K Darney, C Bechaux, F Buratti, E Di Consiglio, L Turco, S Vichi, ... TOXICOLOGY LETTERS 314, S245-S246, 2019 | | 2019 |
| Investigating human cytochrome P450-related variability using PBK models for chemical risk assessment K Darney, A Gkrillas, E Testai, F Buratti, E Di Consiglio, L Turco, S Vichi, ... TOXICOLOGY LETTERS 314, S244-S244, 2019 | | 2019 |
| Developing TK databases and tools to support food safety assessment JL Dorne, B Amzal, N Quignot, W Wiecek, C Bechaux, K Darney, A Grech, ... 54. Congress of the European Societies of Toxicology (EUROTOX 2018) 295 …, 2018 | | 2018 |
