| Family history of renal disease severity predicts the mutated gene in ADPKD M Barua, O Cil, AD Paterson, K Wang, N He, E Dicks, P Parfrey, Y Pei Journal of the American Society of Nephrology 20 (8), 1833-1838, 2009 | 168 | 2009 |
| CFTR activator increases intestinal fluid secretion and normalizes stool output in a mouse model of constipation O Cil, PW Phuan, S Lee, J Tan, PM Haggie, MH Levin, L Sun, ... Cellular and molecular gastroenterology and hepatology 2 (3), 317-327, 2016 | 79 | 2016 |
| Genetic abnormalities and prognosis in patients with congenital and infantile nephrotic syndrome O Cil, N Besbas, A Duzova, R Topaloglu, A Peco-Antić, E Korkmaz, ... Pediatric nephrology 30, 1279-1287, 2015 | 51 | 2015 |
| Small-molecule inhibitors of pendrin potentiate the diuretic action of furosemide O Cil, PM Haggie, P Phuan, JA Tan, AS Verkman Journal of the American Society of Nephrology 27 (12), 3706-3714, 2016 | 50 | 2016 |
| Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins O Cil, PW Phuan, AM Gillespie, S Lee, L Tradtrantip, J Yin, M Tse, ... The FASEB Journal 31 (2), 751, 2017 | 47 | 2017 |
| SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation PM Haggie, O Cil, S Lee, JA Tan, AA Rivera, PW Phuan, AS Verkman JCI insight 3 (14), 2018 | 43 | 2018 |
| Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea T Duan, O Cil, JR Thiagarajah, AS Verkman JCI insight 4 (4), 2019 | 42 | 2019 |
| Substituted 2-acylaminocycloalkylthiophene-3-carboxylic acid arylamides as inhibitors of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A) EC Truong, PW Phuan, AL Reggi, L Ferrera, LJV Galietta, SE Levy, ... Journal of medicinal chemistry 60 (11), 4626-4635, 2017 | 39 | 2017 |
| High-potency phenylquinoxalinone cystic fibrosis transmembrane conductance regulator (CFTR) activators JH Son, JS Zhu, PW Phuan, O Cil, AP Teuthorn, CK Ku, S Lee, ... Journal of medicinal chemistry 60 (6), 2401-2410, 2017 | 36 | 2017 |
| A small molecule inhibitor of the chloride channel TMEM16A blocks vascular smooth muscle contraction and lowers blood pressure in spontaneously hypertensive rats O Cil, X Chen, HRA Page, SN Baldwin, MC Jordan, PM Thwe, ... Kidney international 100 (2), 311-320, 2021 | 26 | 2021 |
| Nanomolar-potency 1, 2, 4-triazoloquinoxaline inhibitors of the kidney urea transporter UT-A1 S Lee, O Cil, E Diez-Cecilia, MO Anderson, AS Verkman Journal of medicinal chemistry 61 (7), 3209-3217, 2018 | 26 | 2018 |
| Salt-sparing diuretic action of a water-soluble urea analog inhibitor of urea transporters UT-A and UT-B in rats O Cil, C Esteva-Font, ST Tas, T Su, S Lee, MO Anderson, M Ertunc, ... Kidney international 88 (2), 311-320, 2015 | 26 | 2015 |
| Monogenic causes of proteinuria in children O Cil, F Perwad Frontiers in medicine 5, 55, 2018 | 24 | 2018 |
| Diuresis and reduced urinary osmolality in rats produced by small-molecule UT-A-selective urea transport inhibitors C Esteva-Font, O Cil, PW Phuan, T Su, S Lee, MO Anderson, AS Verkman The FASEB Journal 28 (9), 3878, 2014 | 23 | 2014 |
| Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation O Cil, PW Phuan, JH Son, JS Zhu, CK Ku, NA Tabib, AP Teuthorn, ... Translational Research 182, 14-26. e4, 2017 | 21 | 2017 |
| Repurposing calcium-sensing receptor agonist cinacalcet for treatment of CFTR-mediated secretory diarrheas AA Oak, PD Chhetri, AA Rivera, AS Verkman, O Cil JCI insight 6 (4), 2021 | 20 | 2021 |
| Inhibition of CFTR-mediated intestinal chloride secretion as potential therapy for bile acid diarrhea T Duan, O Cil, CM Tse, R Sarker, R Lin, M Donowitz, AS Verkman The FASEB Journal 33 (10), 10924, 2019 | 19 | 2019 |
| 4, 8-Dimethylcoumarin inhibitors of intestinal anion exchanger slc26a3 (downregulated in adenoma) for anti-absorptive therapy of constipation S Lee, O Cil, PM Haggie, AS Verkman Journal of medicinal chemistry 62 (17), 8330-8337, 2019 | 19 | 2019 |
| Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A O Cil, MO Anderson, R Yen, B Kelleher, TL Huynh, Y Seo, SP Nilsen, ... The FASEB Journal 33 (10), 11247, 2019 | 18 | 2019 |
| Small-molecule inhibitor of intestinal anion exchanger SLC26A3 for treatment of hyperoxaluria and nephrolithiasis O Cil, T Chu, S Lee, PM Haggie, AS Verkman JCI insight 7 (13), 2022 | 16 | 2022 |
