Distinct conformational states of SARS-CoV-2 spike protein Y Cai, J Zhang, T Xiao, H Peng, SM Sterling, RM Walsh, S Rawson, ... Science 369 (6511), 1586-1592, 2020 | 1136 | 2020 |
The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy V Postis, S Rawson, JK Mitchell, SC Lee, RA Parslow, TR Dafforn, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (2), 496-501, 2015 | 231 | 2015 |
Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants Y Cai, J Zhang, T Xiao, CL Lavine, S Rawson, H Peng, H Zhu, K Anand, ... Science 373 (6555), 642-648, 2021 | 227 | 2021 |
Architecture of autoinhibited and active BRAF–MEK1–14-3-3 complexes E Park, S Rawson, K Li, BW Kim, SB Ficarro, GGD Pino, H Sharif, ... Nature 575 (7783), 545-550, 2019 | 224 | 2019 |
Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states ANA Agip, JN Blaza, HR Bridges, C Viscomi, S Rawson, SP Muench, ... Nature structural & molecular biology 25 (7), 548-556, 2018 | 220 | 2018 |
Using a SMALP platform to determine a sub-nm single particle cryo-EM membrane protein structure M Parmar, S Rawson, CA Scarff, A Goldman, TR Dafforn, SP Muench, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (2), 378-383, 2018 | 142 | 2018 |
NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation L Andreeva, L David, S Rawson, C Shen, T Pasricha, P Pelegrin, H Wu Cell 184 (26), 6299-6312. e22, 2021 | 136 | 2021 |
Structural insight into eukaryotic sterol transport through Niemann-Pick type C proteins MBL Winkler, RT Kidmose, M Szomek, K Thaysen, S Rawson, SP Muench, ... Cell 179 (2), 485-497. e18, 2019 | 131 | 2019 |
Structure of a nascent membrane protein as it folds on the BAM complex D Tomasek, S Rawson, J Lee, JS Wzorek, SC Harrison, Z Li, D Kahne Nature 583 (7816), 473-478, 2020 | 119 | 2020 |
Collection, pre-processing and on-the-fly analysis of data for high-resolution, single-particle cryo-electron microscopy RF Thompson, MG Iadanza, EL Hesketh, S Rawson, NA Ranson Nature protocols 14 (1), 100-118, 2019 | 82 | 2019 |
The changing landscape of membrane protein structural biology through developments in electron microscopy S Rawson, S Davies, JD Lippiat, SP Muench Molecular membrane biology 33 (1-2), 12-22, 2016 | 62 | 2016 |
Dynamic oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis M Madej, JBR White, Z Nowakowska, S Rawson, C Scavenius, JJ Enghild, ... Nature Microbiology, 1016–1025, 2020 | 55 | 2020 |
Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81 KJ Susa, S Rawson, AC Kruse, SC Blacklow Science 371 (6526), 300-305, 2021 | 44 | 2021 |
Methods to account for movement and flexibility in cryo-EM data processing S Rawson, MG Iadanza, NA Ranson, SP Muench Methods 100, 35-41, 2016 | 42 | 2016 |
Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights S Rawson, C Phillips, M Huss, F Tiburcy, H Wieczorek, J Trinick, ... Structure 23 (3), 461-471, 2015 | 41 | 2015 |
PA1b inhibitor binding to subunits c and e of the vacuolar ATPase reveals its insecticidal mechanism SP Muench, S Rawson, V Eyraud, AF Delmas, P Da Silva, C Phillips, ... Journal of Biological Chemistry 289 (23), 16399-16408, 2014 | 40 | 2014 |
Cryo-EM structure of the RADAR supramolecular anti-phage defense complex B Duncan-Lowey, N Tal, AG Johnson, S Rawson, ML Mayer, S Doron, ... Cell 186 (5), 987-998. e15, 2023 | 33 | 2023 |
Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM S Rawson, C Bisson, DL Hurdiss, A Fazal, MJ McPhillie, SE Sedelnikova, ... Proceedings of the National Academy of Sciences 115 (8), 1795-1800, 2018 | 32 | 2018 |
X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery K Amporndanai, RM Johnson, PM O'Neill, CWG Fishwick, AH Jamson, ... IUCrJ 5 (2), 200-210, 2018 | 27 | 2018 |
pH regulates potassium conductance and drives a constitutive proton current in human TMEM175 W Zheng, C Shen, L Wang, S Rawson, WJ Xie, C Nist-Lund, J Wu, Z Shen, ... Science advances 8 (12), eabm1568, 2022 | 26 | 2022 |