TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer L Caja, F Dituri, S Mancarella, D Caballero-Diaz, A Moustakas, ... International journal of molecular sciences 19 (5), 1294, 2018 | 319 | 2018 |
Biological applications of LbL multilayer capsules: From drug delivery to sensing LL Del Mercato, MM Ferraro, F Baldassarre, S Mancarella, V Greco, ... Advances in colloid and interface science 207, 139-154, 2014 | 155 | 2014 |
The interactivity between TGFβ and BMP signaling in organogenesis, fibrosis, and cancer F Dituri, C Cossu, S Mancarella, G Giannelli Cells 8 (10), 1130, 2019 | 113 | 2019 |
TGF-β as multifaceted orchestrator in HCC progression: signaling, EMT, immune microenvironment, and novel therapeutic perspectives F Dituri, S Mancarella, A Cigliano, G Giannelli Seminars in liver disease 39 (01), 053-069, 2019 | 101 | 2019 |
Hepatic stellate cells induce hepatocellular carcinoma cell resistance to sorafenib through the laminin‐332/α3 integrin axis recovery of focal adhesion kinase ubiquitination A Azzariti, S Mancarella, L Porcelli, AE Quatrale, A Caligiuri, L Lupo, ... Hepatology 64 (6), 2103-2117, 2016 | 90 | 2016 |
Polymer‐coated magnetic nanoparticles for curcumin delivery to cancer cells S Mancarella, V Greco, F Baldassarre, D Vergara, M Maffia, S Leporatti Macromolecular Bioscience 15 (10), 1365-1374, 2015 | 73 | 2015 |
Signalling networks in cholangiocarcinoma: Molecular pathogenesis, targeted therapies and drug resistance L Fouassier, M Marzioni, MB Afonso, S Dooley, K Gaston, G Giannelli, ... Liver International 39, 43-62, 2019 | 71 | 2019 |
Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis S Mancarella, G Serino, F Dituri, A Cigliano, S Ribback, J Wang, X Chen, ... Cell Death & Differentiation 27 (8), 2330-2343, 2020 | 52 | 2020 |
Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma V Infantino, F Dituri, P Convertini, A Santarsiero, F Palmieri, S Todisco, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (1), 38-47, 2019 | 45 | 2019 |
NGS-based transcriptome profiling reveals biomarkers for companion diagnostics of the TGF-β receptor blocker galunisertib in HCC Y Cao, R Agarwal, F Dituri, L Lupo, P Trerotoli, S Mancarella, P Winter, ... Cell death & disease 8 (2), e2634-e2634, 2017 | 44 | 2017 |
Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression B Rani, A Malfettone, F Dituri, J Soukupova, L Lupo, S Mancarella, ... Cell Death & Disease 9 (3), 373, 2018 | 36 | 2018 |
Impaired anti-tumor T cell response in hepatocellular carcinoma N Chaoul, S Mancarella, L Lupo, G Giannelli, F Dituri Cancers 12 (3), 627, 2020 | 29 | 2020 |
Validation of hepatocellular carcinoma experimental models for TGF-β promoting tumor progression S Mancarella, S Krol, A Crovace, S Leporatti, F Dituri, M Frusciante, ... Cancers 11 (10), 1510, 2019 | 25 | 2019 |
Proteoglycan-4 is correlated with longer survival in HCC patients and enhances sorafenib and regorafenib effectiveness via CD44 in vitro F Dituri, R Scialpi, TA Schmidt, M Frusciante, S Mancarella, LG Lupo, ... Cell Death & Disease 11 (11), 984, 2020 | 20 | 2020 |
The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease A Cigliano, S Zhang, S Ribback, S Steinmann, M Sini, CE Ament, ... Journal of Experimental & Clinical Cancer Research 41 (1), 192, 2022 | 15 | 2022 |
Proteoglycans in cancer: friends or enemies? A special focus on hepatocellular carcinoma F Dituri, G Gigante, R Scialpi, S Mancarella, I Fabregat, G Giannelli Cancers 14 (8), 1902, 2022 | 14 | 2022 |
Direct and indirect effect of TGFβ on treg transendothelial recruitment in HCC tissue microenvironment F Dituri, S Mancarella, G Serino, N Chaoul, LG Lupo, E Villa, I Fabregat, ... International Journal of Molecular Sciences 22 (21), 11765, 2021 | 13 | 2021 |
Calcium regulates HCC proliferation as well as EGFR recycling/degradation and could be a new therapeutic target in HCC TME Modica, F Dituri, S Mancarella, C Pisano, I Fabregat, G Giannelli Cancers 11 (10), 1588, 2019 | 11 | 2019 |
Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study R Agarwal, Y Cao, K Hoffmeier, N Krezdorn, L Jost, AR Meisel, R Jüngling, ... Cell Death & Disease 8 (6), e2867-e2867, 2017 | 11 | 2017 |
CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype S Mancarella, G Serino, I Gigante, A Cigliano, S Ribback, P Sanese, ... Journal of Experimental & Clinical Cancer Research 41 (1), 65, 2022 | 8 | 2022 |