P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation D Pan, RT Amison, Y Riffo-Vasquez, D Spina, SJ Cleary, MJ Wakelam, ... Blood, The Journal of the American Society of Hematology 125 (7), 1146-1158, 2015 | 81 | 2015 |
Platelets in neutrophil recruitment to sites of inflammation S Pitchford, D Pan, HCE Welch Current opinion in hematology 24 (1), 23-31, 2017 | 80 | 2017 |
GPCR activation of Ras and PI3Kγ in neutrophils depends on PLCβ2/β3 and the RasGEF RasGRP4 S Suire, C Lécureuil, KE Anderson, G Damoulakis, I Niewczas, ... The EMBO journal 31 (14), 3118-3129, 2012 | 75 | 2012 |
The regulatory subunits of PI3Kγ control distinct neutrophil responses A Deladeriere, L Gambardella, D Pan, KE Anderson, PT Hawkins, ... Science signaling 8 (360), ra8-ra8, 2015 | 46 | 2015 |
Norbin stimulates the catalytic activity and plasma membrane localization of the guanine-nucleotide exchange factor P-Rex1 D Pan, MA Barber, K Hornigold, MJ Baker, JM Toth, D Oxley, HCE Welch Journal of Biological Chemistry 291 (12), 6359-6375, 2016 | 30 | 2016 |
Small GTPases and their guanine-nucleotide exchange factors and GTPase-activating proteins in neutrophil recruitment MJ Baker, D Pan, HCE Welch Current opinion in hematology 23 (1), 44-54, 2016 | 30 | 2016 |
Social mixing with other children during infancy enhances antibody response to a pneumococcal conjugate vaccine in early childhood P Salt, C Banner, S Oh, L Yu, S Lewis, D Pan, D Griffiths, B Ferry, ... Clinical and Vaccine Immunology 14 (5), 593-599, 2007 | 28 | 2007 |
COX-1 mediates IL-33–induced extracellular signal-regulated kinase activation in mast cells: Implications for aspirin sensitivity D Pan, KM Buchheit, SK Samuchiwal, T Liu, H Cirka, H Raff, JA Boyce Journal of Allergy and Clinical Immunology 143 (3), 1047-1057. e8, 2019 | 26 | 2019 |
Rac GTPase-activating protein (Rac GAP) α1-Chimaerin undergoes proteasomal degradation and is stabilized by diacylglycerol signaling in neurons JRK Marland, DX Pan, PC Buttery Journal of Biological Chemistry 286 (1), 199-207, 2011 | 15 | 2011 |
The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection C Pantarelli, D Pan, S Chetwynd, AK Stark, K Hornigold, P Machin, ... Blood advances 5 (16), 3076-3091, 2021 | 11 | 2021 |
Stimulation of platelet P2Y1 receptors by different endogenous nucleotides leads to functional selectivity via biased signalling KL Arkless, D Pan, M Shankar‐Hari, RT Amison, CP Page, KM Rahman, ... British journal of pharmacology 181 (4), 564-579, 2024 | 8 | 2024 |
Small-molecule inhibitors of P-Rex guanine-nucleotide exchange factors CD Lawson, K Hornigold, D Pan, I Niewczas, S Andrews, J Clark, ... Small GTPases 13 (1), 307-326, 2022 | 4 | 2022 |
Exploring bias in platelet P2Y1 signalling: Host defence versus haemostasis D Pan, G Ladds, KM Rahman, SC Pitchford British Journal of Pharmacology 181 (4), 580-592, 2024 | 2 | 2024 |
The regulatory subunits of PI3K control distinct neutrophil responses A Deladeriere, L Gambardella, D Pan, KE Anderson, PT Hawkins, ... Sci. Signal 8, 0 | 2 | |
Platelet purinergic receptors and non‐thrombotic diseases SC Pitchford, D Pan British Journal of Pharmacology 181 (4), 513-514, 2024 | 1 | 2024 |
P2Y14 receptor activation of platelets induces Ca2+ mobilization and Rho-GTPase dependent motility that requires an interaction with P2Y1 receptors. M Hossain, D Pan, KL Arkless, CP Page, KM Rahman, KS Authi, ... Authorea, 2024 | 1 | 2024 |
Platelet-specific P2Y1 receptor deficient mice have suppressed leukocyte recruitment in response to lipopolysaccharide. D Pan, T Oralman, R Evans, O Baker, G Cocks, CP Page, SC Pitchford bioRxiv, 2024.11. 04.621858, 2024 | | 2024 |
Norbin, a GPCR-adaptor protein and regulator of Prex1, suppresses neutrophil-dependent immunity C Pantarelli, D Pan, AK Stark, H Welch EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 49, 206-207, 2019 | | 2019 |
Role of Norbin, a GPCR-adaptor and regulator of P-Rex1, in neutrophil-dependent immunity C Pantarelli, D Pan, AK Stark, HC Welch EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 48, 46-46, 2018 | | 2018 |
Regulation of neutrophil responses by P-rex and norbin C Pantarelli, D Pan, H Welch EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 47, 46-46, 2017 | | 2017 |