Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites. CT Hotta, ML Gazarini, FH Beraldo, FP Varotti, C Lopes, RP Markus, ... Nature cell biology 2 (7), 466-468, 2000 | 212 | 2000 |
Plant-derived antimalarial agents: new leads and efficient phythomedicines. Part I. Alkaloids AB Oliveira, MF Dolabela, FC Braga, RLRP Jácome, FP Varotti, ... Anais da Academia Brasileira de Ciencias 81, 715-740, 2009 | 203 | 2009 |
Synthesis, antimalarial activity, and intracellular targets of MEFAS, a new hybrid compound derived from mefloquine and artesunate F de Pilla Varotti, ACC Botelho, AA Andrade, RC de Paula, ... Antimicrobial Agents and Chemotherapy 52 (11), 3868-3874, 2008 | 105 | 2008 |
Effect of the antimicrobial peptide gomesin against different life stages of Plasmodium spp. CK Moreira, FG Rodrigues, A Ghosh, FP Varotti, A Miranda, S Daffre, ... Experimental parasitology 116 (4), 346-353, 2007 | 78 | 2007 |
Plasmodium falciparum malaria parasites display a THG-sensitive Ca2+ pool FP Varotti, FH Beraldo, ML Gazarini, CRS Garcia Cell Calcium 33 (2), 137-144, 2003 | 75 | 2003 |
Antioxidant, Antibacterial and Antitumor Activity of Ethanolic Extract of the Psidium guajava Leaves TV Braga, RGR das Dores, CS Ramos, FCG Evangelista, ... American Journal of Plant Sciences 5 (23), 3492, 2014 | 64 | 2014 |
Antiplasmodial Activity of Aryltetralone Lignans from Holostylis reniformis VF de Andrade-Neto, T da Silva, LMX Lopes, VE do Rosário, ... Antimicrobial agents and chemotherapy 51 (7), 2346-2350, 2007 | 59 | 2007 |
Synthesis and antimalarial activity of hydroxyethylpiperazine derivatives W Cunico, CRB Gomes, M Moreth, DP Manhanini, IH Figueiredo, ... European journal of medicinal chemistry 44 (3), 1363-1368, 2009 | 58 | 2009 |
Co-nanoencapsulation of antimalarial drugs increases their in vitro efficacy against Plasmodium falciparum and decreases their toxicity to Caenorhabditis elegans K Velasques, TR Maciel, AHC Dal Forno, FEG Teixeira, AL da Fonseca, ... European Journal of Pharmaceutical Sciences 118, 1-12, 2018 | 51 | 2018 |
Synthesis, in vitro antimalarial activity and in silico studies of hybrid kauranoid 1, 2, 3-triazoles derived from naturally occurring diterpenes JO Santos, GR Pereira, GC Brandão, TF Borgati, LM Arantes, RC Paula, ... Journal of the Brazilian Chemical Society 27, 551-565, 2016 | 43 | 2016 |
21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na, K-ATPase and epithelial tight junctions SC Rocha, MTC Pessoa, LDR Neves, SLG Alves, LM Silva, HL Santos, ... PLoS One 9 (10), e108776, 2014 | 41 | 2014 |
Enhanced activity of mefloquine and artesunic acid against Plasmodium falciparum in vitro and P. berghei in mice by combination with ciprofloxacin AA Andrade, F de Pilla Varotti, IO de Freitas, MVN de Souza, ... European journal of pharmacology 558 (1-3), 194-198, 2007 | 40 | 2007 |
J. Braz. Chem. Soc. AM Santos, GR Pereira, GC Brandão, TF Borgati, LM Arantes, C de Paula, ... | 37 | 2015 |
Antimalarial activity of 4-metoxychalcones: Docking studies as falcipain/plasmepsin inhibitors, ADMET and lipophilic efficiency analysis to identify a putative oral lead candidate ME De Oliveira, G Cenzi, RR Nunes, CR Andrighetti, ... Molecules 18 (12), 15276-15287, 2013 | 36 | 2013 |
Synthesis, cytotoxicity and antiplasmodial activity of novel ent-kaurane derivatives R Batista, PA García, MA Castro, JMM Del Corral, NL Speziali, FP Varotti, ... European Journal of Medicinal Chemistry 62, 168-176, 2013 | 36 | 2013 |
In vitro and in vivo antimalarial potential of oleoresin obtained from Copaifera reticulata Ducke (Fabaceae) in the Brazilian Amazon rainforest GAG de Souza, NC da Silva, J de Souza, KRM de Oliveira, ... Phytomedicine 24, 111-118, 2017 | 35 | 2017 |
Brazilian malaria molecular targets (BraMMT): selected receptors for virtual high-throughput screening experiments RR Nunes, AL Fonseca, ACS Pinto, EHB Maia, AM Silva, FP Varotti, ... Memórias do Instituto Oswaldo Cruz 114, e180465, 2019 | 34 | 2019 |
Synthesis, antimalarial evaluation and molecular modeling studies of hydroxyethylpiperazines, potential aspartyl protease inhibitors, part 2 W Cunico, CRB Gomes, V Facchinetti, M Moreth, C Penido, ... European journal of medicinal chemistry 44 (9), 3816-3820, 2009 | 34 | 2009 |
Hypervalent organotellurium compounds as inhibitors of P. falciparum calcium-dependent cysteine proteases SEC Maluf, PMS Melo, FP Varotti, ML Gazarini, RLOR Cunha, ... Parasitology international 65 (1), 20-22, 2016 | 31 | 2016 |
Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells GD Da Silva, MG Da Silva, EM Souza, A Barison, SC Simões, FP Varotti, ... Molecules 17 (9), 10331-10343, 2012 | 30 | 2012 |