A Design of Experiments (DoE) Approach Accelerates the Optimization of Copper-Mediated 18F-Fluorination Reactions of Arylstannanes GD Bowden, BJ Pichler, A Maurer Scientific reports 9 (1), 11370, 2019 | 142 | 2019 |
Alpha-synuclein PET tracer development—an overview about current efforts Š Korat, NSR Bidesi, F Bonanno, A Di Nanni, ANN Hoàng, K Herfert, ... Pharmaceuticals 14 (9), 847, 2021 | 70 | 2021 |
Scalable 18 F processing conditions for copper-mediated radiofluorination chemistry facilitate DoE optimization studies and afford an improved synthesis of [18 F] olaparib GD Bowden, N Chailanggar, BJ Pichler, A Maurer Organic & biomolecular chemistry 19 (32), 6995-7000, 2021 | 23 | 2021 |
PET/MRI enables simultaneous in vivo quantification of β-cell mass and function FC Michelotti, G Bowden, A Küppers, L Joosten, J Maczewsky, ... Theranostics 10 (1), 398, 2020 | 23 | 2020 |
DoE Optimization Empowers the Automated Preparation of Enantiomerically Pure [18F]Talazoparib and its In Vivo Evaluation as a PARP Radiotracer GD Bowden, S Stotz, J Kinzler, C Geibel, M Lämmerhofer, BJ Pichler, ... Journal of Medicinal Chemistry 64 (21), 15690-15701, 2021 | 20 | 2021 |
Radiochemistry: A Hot Field with Opportunities for Cool Chemistry GD Bowden, PJH Scott, E Boros ACS Central Science 9 (12), 2183-2195, 2023 | 7 | 2023 |
Covalent 18F-Radiotracers for SNAPTag: A New Toolbox for Reporter Gene Imaging S Stotz, GD Bowden, JM Cotton, BJ Pichler, A Maurer Pharmaceuticals 14 (9), 897, 2021 | 7 | 2021 |
2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, 18F-Labeling and Preclinical PET Imaging FC Maier, A Schweifer, VL Damaraju, CE Cass, GD Bowden, ... Pharmaceuticals 12 (1), 31, 2019 | 7 | 2019 |
Acetuino—A Handy Open-Source Radiochemistry Module for the Preparation of [1-11C]Acetate A Maurer, G Bowden, J Cotton, C Parl, MA Krueger, BJ Pichler SLAS TECHNOLOGY: Translating Life Sciences Innovation 24 (3), 321-329, 2019 | 5 | 2019 |
Machine learning identifies multi-parametric functional PET/MR imaging cluster to predict radiation resistance in preclinical head and neck cancer models S Boeke, RM Winter, S Leibfarth, MA Krueger, G Bowden, J Cotton, ... European Journal of Nuclear Medicine and Molecular Imaging 50 (10), 3084-3096, 2023 | 3 | 2023 |
Intratumoral in vivo staging of breast cancer by multi-tracer PET and advanced analysis J Griessinger, J Schwab, Q Chen, A Kühn, J Cotton, G Bowden, ... NPJ Breast Cancer 8 (1), 41, 2022 | 3 | 2022 |
Automated synthesis of [F-18] O-6-[(4-[F-18] fluoro) benzyl] guanine ([F-18] pFBG) via [F-18]-fluorobenzyl alcohol ([F-18] 4FBnOH) from an optimized copper mediated … G Bowden, A Franke, B Pichler, A Maurer Journal of Labelled Compounds and Radiopharmaceuticals 62, S329-S331, 2019 | 3 | 2019 |
A Fluorescent Probe as a Lead Compound for a Selective α-Synuclein PET Tracer: Development of a Library of 2-Styrylbenzothiazoles and Biological Evaluation of [18F]PFSB … A Di Nanni, RS Saw, UM Battisti, GD Bowden, A Boeckermann, ... ACS omega 8 (34), 31450-31467, 2023 | 2 | 2023 |
The structural combination of SIL and MODAG scaffolds fails to enhance binding to α-synuclein but reveals promising affinity to amyloid β A Di Nanni, RS Saw, GD Bowden, NSR Bidesi, K Bjerregaard-Andersen, ... Molecules 28 (10), 4001, 2023 | 2 | 2023 |
Development of High-Throughput Experimentation Approaches for Rapid Radiochemical Exploration EW Webb, K Cheng, WP Winton, BJC Klein, GD Bowden, M Horikawa, ... Journal of the American Chemical Society 146 (15), 10581-10590, 2024 | 1 | 2024 |
[18F]pFBC, a Covalent CLIP-Tag Radiotracer for Detection of Viral Reporter Gene Transfer in the Murine Brain GD Bowden, S Stotz, G Dunkel, S Haas, E Kimmerle, M Schaller, ... Bioconjugate Chemistry, 2024 | 1 | 2024 |
Novel pyrazolethiazole derivatives as new high affinity and selective ligands for alpha-synuclein fibrils as potential PET tracers for Parkinson’s disease F Bonanno, RS Saw, K Herfert, B Pichler, G Bowden, A Maurer Nuclear Medicine and Biology 108, S90-S91, 2022 | 1 | 2022 |
A fluorescent probe as a lead compound for a potential α-syn PET tracer: design and development of a library of RB1 derivatives A Di Nanni, U Battisti, N Bidesi, RS Saw, K Herfert, B Pichler, G Bowden, ... Nuclear Medicine and Biology 108, S94, 2022 | 1 | 2022 |
Optimization of the copper mediated [F-18] radiofluorination (CMRF) of arylstannane precursors using a" design of experiments"(DoE) approach G Bowden, B Pichler, A Maurer JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 62, S339-S340, 2019 | 1 | 2019 |
Scope and Automation of the Copper-Mediated Radiocyanation of Aryl Silanes J Wright, R Ma, C McCarthy, G Kaup, X Shao, J Priest, E Webb, K Cheng, ... Journal of Nuclear Medicine 65 (supplement 2), 242006-242006, 2024 | | 2024 |