Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans A Alpi, P Pasierbek, A Gartner, J Loidl Chromosoma 112, 6-16, 2003 | 281 | 2003 |
A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment W Wunderlich, I Fialka, D Teis, A Alpi, A Pfeifer, RG Parton, F Lottspeich, ... The Journal of cell biology 152 (4), 765-776, 2001 | 252 | 2001 |
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI AF Alpi, PE Pace, MM Babu, KJ Patel Molecular cell 32 (6), 767-777, 2008 | 234 | 2008 |
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway G Mosedale, W Niedzwiedz, A Alpi, F Perrina, JB Pereira-Leal, ... Nature structural & molecular biology 12 (9), 763-771, 2005 | 225 | 2005 |
Two distinct types of E3 ligases work in unison to regulate substrate ubiquitylation DC Scott, DY Rhee, DM Duda, IR Kelsall, JL Olszewski, JA Paulo, ... Cell 166 (5), 1198-1214. e24, 2016 | 216 | 2016 |
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism DM Duda, JL Olszewski, JP Schuermann, I Kurinov, DJ Miller, A Nourse, ... Structure 21 (6), 1030-1041, 2013 | 143 | 2013 |
C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein S Ahmed, A Alpi, MO Hengartner, A Gartner Current Biology 11 (24), 1934-1944, 2001 | 141 | 2001 |
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin‐RING ligase complexes IR Kelsall, DM Duda, JL Olszewski, K Hofmann, A Knebel, F Langevin, ... The EMBO journal 32 (21), 2848-2860, 2013 | 107 | 2013 |
The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair AP Bailly, A Freeman, J Hall, AC Déclais, A Alpi, DMJ Lilley, S Ahmed, ... PLoS genetics 6 (7), e1001025, 2010 | 107 | 2010 |
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination A Alpi, F Langevin, G Mosedale, YJ Machida, A Dutta, KJ Patel Molecular and cellular biology, 2007 | 106 | 2007 |
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase DC Scott, JT Hammill, J Min, DY Rhee, M Connelly, VO Sviderskiy, ... Nature chemical biology 13 (8), 850-857, 2017 | 96 | 2017 |
E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin C MacKay, E Carroll, AFM Ibrahim, A Garg, GJ Inman, RT Hay, AF Alpi Cancer research 74 (8), 2246-2257, 2014 | 95 | 2014 |
The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair IV Rosado, W Niedzwiedz, AF Alpi, KJ Patel Nucleic acids research 37 (13), 4360-4370, 2009 | 95 | 2009 |
Monoubiquitylation in the Fanconi anemia DNA damage response pathway AF Alpi, KJ Patel DNA repair 8 (4), 430-435, 2009 | 92 | 2009 |
Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line C Wicky, A Alpi, M Passannante, A Rose, A Gartner, F Müller Molecular and cellular biology, 2004 | 87 | 2004 |
AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia EL Virts, A Jankowska, C Mackay, MF Glaas, C Wiek, SL Kelich, ... Human molecular genetics 24 (18), 5093-5108, 2015 | 75 | 2015 |
Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 AF Alpi, V Chaugule, H Walden Biochemical Journal 473 (20), 3401-3419, 2016 | 67 | 2016 |
ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection R Hüttenhain, J Xu, LA Burton, DE Gordon, JF Hultquist, JR Johnson, ... Cell host & microbe 26 (1), 86-99. e7, 2019 | 53 | 2019 |
Functional Dissection of Caenorhabditis elegans CLK-2/TEL2 Cell Cycle Defects during Embryogenesis and Germline Development SC Moser, S von Elsner, I Büssing, A Alpi, R Schnabel, A Gartner PLoS Genetics 5 (4), e1000451, 2009 | 53 | 2009 |
GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme D Sherpa, J Chrustowicz, S Qiao, CR Langlois, LA Hehl, ... Molecular Cell 81 (11), 2445-2459. e13, 2021 | 51 | 2021 |