FMNL2 drives actin-based protrusion and migration downstream of Cdc42 J Block, D Breitsprecher, S Kühn, M Winterhoff, F Kage, R Geffers, ... Current Biology 22 (11), 1005-1012, 2012 | 230 | 2012 |
Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion A Chazeau, A Mehidi, D Nair, JJ Gautier, C Leduc, I Chamma, F Kage, ... The EMBO journal 33 (23), 2745-2764, 2014 | 143 | 2014 |
FMNL formins boost lamellipodial force generation F Kage, M Winterhoff, V Dimchev, J Mueller, T Thalheim, A Freise, ... Nature communications 8 (1), 14832, 2017 | 138 | 2017 |
Distinct interaction sites of Rac GTPase with WAVE regulatory complex have non-redundant functions in vivo M Schaks, SP Singh, F Kage, P Thomason, T Klünemann, A Steffen, ... Current Biology 28 (22), 3674-3684. e6, 2018 | 76 | 2018 |
The structure of FMNL2–Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation S Kühn, C Erdmann, F Kage, J Block, L Schwenkmezger, A Steffen, ... Nature communications 6 (1), 7088, 2015 | 69 | 2015 |
Coordination by Cdc42 of actin, contractility, and adhesion for melanoblast movement in mouse skin EF Woodham, NR Paul, B Tyrrell, HJ Spence, K Swaminathan, ... Current Biology 27 (5), 624-637, 2017 | 50 | 2017 |
Efficiency of lamellipodia protrusion is determined by the extent of cytosolic actin assembly G Dimchev, A Steffen, F Kage, V Dimchev, J Pernier, MF Carlier, K Rottner Molecular Biology of the Cell 28 (10), 1311-1325, 2017 | 47 | 2017 |
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity E Salzer, S Zoghi, MG Kiss, F Kage, C Rashkova, S Stahnke, M Haimel, ... Science immunology 5 (49), eabc3979, 2020 | 46 | 2020 |
FMNL2 and-3 regulate Golgi architecture and anterograde transport downstream of Cdc42 F Kage, A Steffen, A Ellinger, C Ranftler, C Gehre, C Brakebusch, ... Scientific reports 7 (1), 9791, 2017 | 41 | 2017 |
Forces generated by lamellipodial actin filament elongation regulate the WAVE complex during cell migration A Mehidi, F Kage, Z Karatas, M Cercy, M Schaks, A Polesskaya, ... Nature Cell Biology 23 (11), 1148-1162, 2021 | 35 | 2021 |
Induced Arp2/3 complex depletion increases FMNL2/3 formin expression and filopodia formation V Dimchev, I Lahmann, SA Koestler, F Kage, G Dimchev, A Steffen, ... Frontiers in cell and developmental biology 9, 634708, 2021 | 31 | 2021 |
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion S Stahnke, H Döring, C Kusch, DJJ de Gorter, S Dütting, A Guledani, ... Current Biology 31 (10), 2051-2064. e8, 2021 | 28 | 2021 |
On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility S Dolati, F Kage, J Mueller, M Müsken, M Kirchner, G Dittmar, M Sixt, ... Molecular biology of the cell 29 (22), 2674-2686, 2018 | 25 | 2018 |
The WAVE regulatory complex is required to balance protrusion and adhesion in migration JA Whitelaw, K Swaminathan, F Kage, LM Machesky Cells 9 (7), 1635, 2020 | 21 | 2020 |
Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division A Liu, F Kage, HN Higgs Molecular Biology of the Cell 32 (20), ar5, 2021 | 20 | 2021 |
Lamellipodia-like actin networks in cells lacking WAVE regulatory complex F Kage, H Döring, M Mietkowska, M Schaks, F Grüner, S Stahnke, ... Journal of Cell Science 135 (15), jcs260364, 2022 | 18 | 2022 |
RhoG and Cdc42 can contribute to Rac-dependent lamellipodia formation through WAVE regulatory complex-binding M Schaks, H Döring, F Kage, A Steffen, T Klünemann, W Blankenfeldt, ... Small GTPases 12 (2), 122-132, 2021 | 18 | 2021 |
Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria TS Fung, R Chakrabarti, J Kollasser, K Rottner, TEB Stradal, F Kage, ... Current Biology 32 (7), 1577-1592. e8, 2022 | 13 | 2022 |
Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial division F Kage, M Vicente-Manzanares, BC McEwan, AN Kettenbach, HN Higgs Molecular Biology of the Cell 33 (7), ar63, 2022 | 7 | 2022 |
Actin Networks: Adapting to Load through Geometry K Rottner, F Kage Current Biology 27 (23), R1274-R1277, 2017 | 6 | 2017 |