Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2619 | 2018 |
Genome-wide association study identifies 30 loci associated with bipolar disorder EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ... Nature genetics 51 (5), 793-803, 2019 | 1407 | 2019 |
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 845 | 2021 |
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes A Xue, Y Wu, Z Zhu, F Zhang, KE Kemper, Z Zheng, L Yengo, ... Nature communications 9 (1), 2941, 2018 | 719 | 2018 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 631 | 2019 |
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 499 | 2018 |
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood T Qi, Y Wu, J Zeng, F Zhang, A Xue, L Jiang, Z Zhu, K Kemper, L Yengo, ... Nature communications 9 (1), 2282, 2018 | 332 | 2018 |
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.(2018). Genome-wide association analyses identify 44 risk variants and refine the genetic … NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature Genetics 50 (5), 668-681, 0 | 296* | |
Genetic insights into biological mechanisms governing human ovarian ageing KS Ruth, FR Day, J Hussain, A Martínez-Marchal, CE Aiken, A Azad, ... Nature 596 (7872), 393-397, 2021 | 238 | 2021 |
Genetic architectures of childhood-and adult-onset asthma are partly distinct MAR Ferreira, R Mathur, JM Vonk, A Szwajda, B Brumpton, R Granell, ... The American Journal of Human Genetics 104 (4), 665-684, 2019 | 235 | 2019 |
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits E Porcu, S Rüeger, K Lepik, FA Santoni, A Reymond, Z Kutalik Nature communications 10 (1), 3300, 2019 | 232 | 2019 |
Genetic predisposition to mosaic Y chromosome loss in blood DJ Thompson, G Genovese, J Halvardson, JC Ulirsch, DJ Wright, C Terao, ... Nature 575 (7784), 652-657, 2019 | 229 | 2019 |
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances PRHJ Timmers, N Mounier, K Lall, K Fischer, Z Ning, X Feng, ... elife 8, e39856, 2019 | 217 | 2019 |
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19 G Carissimo, W Xu, I Kwok, MY Abdad, YH Chan, SW Fong, KJ Puan, ... Nature communications 11 (1), 5243, 2020 | 163 | 2020 |
Allergic airway diseases in a tropical urban environment are driven by dominant mono‐specific sensitization against house dust mites AK Andiappan, KJ Puan, B Lee, A Nardin, M Poidinger, J Connolly, ... Allergy 69 (4), 501-509, 2014 | 155 | 2014 |
Cell specific eQTL analysis without sorting cells HJ Westra, D Arends, T Esko, MJ Peters, C Schurmann, K Schramm, ... PLoS genetics 11 (5), e1005223, 2015 | 143 | 2015 |
Identification of new susceptibility loci for IgA nephropathy in Han Chinese M Li, JN Foo, JQ Wang, HQ Low, XQ Tang, KY Toh, PR Yin, CC Khor, ... Nature communications 6 (1), 7270, 2015 | 140 | 2015 |
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy H Liu, A Irwanto, X Fu, G Yu, Y Yu, Y Sun, C Wang, Z Wang, Y Okada, ... Nature genetics 47 (3), 267-271, 2015 | 131 | 2015 |
Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles LFW Akshamal M Gamage, Kai Sen Tan, Wharton O Y Chan, Jing Liu, Chee Wah Tan ... PLoS Pathog 7 (16(12)), e1009130, 2020 | 109* | 2020 |
Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus‐specific neutralizing antibody response Z Her, TS Teng, JJL Tan, TH Teo, YW Kam, FM Lum, WWL Lee, C Gabriel, ... EMBO molecular medicine 7 (1), 24-41, 2015 | 109 | 2015 |