Hyperinsulinemia drives diet-induced obesity independently of brain insulin production AE Mehran, NM Templeman, GS Brigidi, GE Lim, KY Chu, X Hu, ... Cell metabolism 16 (6), 723-737, 2012 | 607 | 2012 |
Glucagon-like peptide 1 secretion by the L-cell: the view from within GE Lim, PL Brubaker Diabetes 55 (Supplement_2), S70-S77, 2006 | 260 | 2006 |
Prenatal exposure to nicotine causes postnatal obesity and altered perivascular adipose tissue function YJ Gao, AC Holloway, ZH Zeng, GE Lim, JJ Petrik, WG Foster, RMKW Lee Obesity research 13 (4), 687-692, 2005 | 250 | 2005 |
Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell GE Lim, GJ Huang, N Flora, D LeRoith, CJ Rhodes, PL Brubaker Endocrinology 150 (2), 580-591, 2009 | 220 | 2009 |
A causal role for hyperinsulinemia in obesity NM Templeman, S Skovsø, MM Page, GE Lim, JD Johnson Journal of Endocrinology 232 (3), R173-R183, 2017 | 199 | 2017 |
Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells F Yi, J Sun, GE Lim, IG Fantus, PL Brubaker, T Jin Endocrinology 149 (5), 2341-2351, 2008 | 194 | 2008 |
Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 … AC Holloway, GE Lim, JJ Petrik, WG Foster, KM Morrison, HC Gerstein Diabetologia 48, 2661-2666, 2005 | 156 | 2005 |
Reduced circulating insulin enhances insulin sensitivity in old mice and extends lifespan NM Templeman, S Flibotte, JHL Chik, S Sinha, GE Lim, LJ Foster, ... Cell reports 20 (2), 451-463, 2017 | 141 | 2017 |
14-3-3ζ coordinates adipogenesis of visceral fat GE Lim, T Albrecht, M Piske, K Sarai, JTC Lee, HS Ramshaw, S Sinha, ... Nature communications 6 (1), 7671, 2015 | 72 | 2015 |
Synergistic effects between FSH and 1, 1‐dichloro‐2, 2‐bis (P‐chlorophenyl) ethylene (P, P′‐DDE) on human granulosa cell aromatase activity EV Younglai, AC Holloway, GE Lim, WG Foster Human Reproduction 19 (5), 1089-1093, 2004 | 68 | 2004 |
Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes M Szabat, TB Kalynyak, GE Lim, KY Chu, YH Yang, A Asadi, BK Gage, ... Cell death & disease 2 (11), e232-e232, 2011 | 61 | 2011 |
The rho guanosine 5′-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine … GE Lim, M Xu, J Sun, T Jin, PL Brubaker Endocrinology 150 (12), 5249-5261, 2009 | 55 | 2009 |
Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells T Boothe, GE Lim, H Cen, S Skovsø, M Piske, SN Li, IR Nabi, P Gilon, ... Molecular metabolism 5 (5), 366-378, 2016 | 52 | 2016 |
Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain MM Page, S Skovsø, H Cen, AP Chiu, DA Dionne, DF Hutchinson, GE Lim, ... The FASEB Journal 32 (3), 1196, 2018 | 47 | 2018 |
14-3-3 proteins are essential signalling hubs for beta cell survival GE Lim, M Piske, JD Johnson Diabetologia 56, 825-837, 2013 | 46 | 2013 |
Effects of insulin on human pancreatic cancer progression modeled in vitro MT Chan, GE Lim, S Skovsø, YHC Yang, T Albrecht, EU Alejandro, ... BMC cancer 14, 1-12, 2014 | 44 | 2014 |
Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription EU Alejandro, GE Lim, AE Mehran, X Hu, F Taghizadeh, D Pelipeychenko, ... The FASEB Journal 25 (11), 3884, 2011 | 39 | 2011 |
Is dynamic autocrine insulin signaling possible? A mathematical model predicts picomolar concentrations of extracellular monomeric insulin within human pancreatic islets M Wang, J Li, GE Lim, JD Johnson PLoS One 8 (6), e64860, 2013 | 35 | 2013 |
Ywhaz/14-3-3ζ deletion improves glucose tolerance through a GLP-1-dependent mechanism GE Lim, M Piske, JE Lulo, HS Ramshaw, AF Lopez, JD Johnson Endocrinology 157 (7), 2649-2659, 2016 | 34 | 2016 |
Can 14-3-3 proteins serve as therapeutic targets for the treatment of metabolic diseases? K Diallo, AK Oppong, GE Lim Pharmacological research 139, 199-206, 2019 | 33 | 2019 |