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Madeleine Henley
Madeleine Henley
Scientist, Foghorn Therapeutics
在 mit.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Advances in targeting ‘undruggable’transcription factors with small molecules
MJ Henley, AN Koehler
Nature Reviews Drug Discovery 20 (9), 669-688, 2021
1032021
Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators
AR Henderson, MJ Henley, NJ Foster, AL Peiffer, MS Beyersdorf, ...
Proceedings of the National Academy of Sciences 115 (36), 8960-8965, 2018
252018
Unexpected Specificity within Dynamic Transcriptional Protein-Protein Complexes
MJ Henley, BM Linhares, BS Morgan, CA Fierke, T Cierpicki, A Mapp
Proceedings of the National Academy of Sciences 117 (44), 27346-27353, 2020
242020
Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P
BP Klemm, A Karasik, KJ Kaitany, A Shanmuganathan, MJ Henley, ...
Rna 23 (12), 1860-1873, 2017
172017
A dual-site inhibitor of CBP/p300 KIX is a selective and effective modulator of Myb
ST Joy, MJ Henley, SN De Salle, MS Beyersdorf, IW Vock, AJL Huldin, ...
Journal of the American Chemical Society 143 (37), 15056-15062, 2021
102021
Drugging fuzzy complexes in transcription
BG Su, MJ Henley
Frontiers in Molecular Biosciences 8, 795743, 2021
92021
Crystal structure of O-ethyl N-(ethoxycarbonyl) thiocarbamate
MJ Henley, AM Schrader, VG Young Jr, G Barany
Acta Crystallographica Section E: Crystallographic Communications 71 (10 …, 2015
22015
Nailing Down a Notoriously Elusive Cancer Target: Direct Inhibition of MYC by a Covalent Small Molecule
MJ Henley, SK Doyle, AN Koehler
Cell Chemical Biology 28 (1), 1-3, 2021
12021
Unexpectedly Stable (Chlorocarbonyl)(N-ethoxycarbonylcarbamoyl) disulfane, and Related Compounds That Model the Zumach–Weiss–Kühle (ZWK) Reaction for Synthesis of 1, 2, 4 …
G Barany, D Britton, L Chen, RP Hammer, MJ Henley, AM Schrader, ...
The Journal of Organic Chemistry 80 (22), 11313-11321, 2015
12015
Crystal structure of bis (N-methyl-N-phenylamino) trisulfane
G Barany, MJ Henley, LA Polski, AL Schroll, VG Young Jr
Acta Crystallographica Section E: Crystallographic Communications 71 (7 …, 2015
12015
Preparation, Characterization, and Mechanistic Considerations for 1, 1, 1-Tri (thioacetyl) ethane and 1, 1-Di (thioacetyl) ethene
ES Goebel, MJ Turcotte, MJ Henley, VG Young Jr, G Barany
The Journal of Organic Chemistry 88 (11), 7535-7538, 2023
2023
Crystal structures of (N-methyl-N-phenylamino)(N-methyl-N-phenylcarbamoyl) sulfide and the corresponding disulfane
MJ Henley, AL Schroll, VG Young Jr, G Barany
Acta Crystallographica Section E: Crystallographic Communications 71 (11 …, 2015
2015
Mechanistic Insights Into the Zumach-Weiss-Kühle Synthesis of Dithiasuccinoyl (Dts)-Protected Amines
MJ Henley, MJ Barany, L Chen, RP Hammer, AM Schrader, VG Young Jr, ...
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