Advances in targeting ‘undruggable’transcription factors with small molecules MJ Henley, AN Koehler Nature Reviews Drug Discovery 20 (9), 669-688, 2021 | 202 | 2021 |
Unexpected Specificity within Dynamic Transcriptional Protein-Protein Complexes MJ Henley, BM Linhares, BS Morgan, CA Fierke, T Cierpicki, A Mapp Proceedings of the National Academy of Sciences 117 (44), 27346-27353, 2020 | 34 | 2020 |
Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators AR Henderson, MJ Henley, NJ Foster, AL Peiffer, MS Beyersdorf, ... Proceedings of the National Academy of Sciences 115 (36), 8960-8965, 2018 | 31 | 2018 |
A dual-site inhibitor of CBP/p300 KIX is a selective and effective modulator of Myb ST Joy, MJ Henley, SN De Salle, MS Beyersdorf, IW Vock, AJL Huldin, ... Journal of the American Chemical Society 143 (37), 15056-15062, 2021 | 25 | 2021 |
Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P BP Klemm, A Karasik, KJ Kaitany, A Shanmuganathan, MJ Henley, ... Rna 23 (12), 1860-1873, 2017 | 22 | 2017 |
Drugging fuzzy complexes in transcription BG Su, MJ Henley Frontiers in Molecular Biosciences 8, 795743, 2021 | 15 | 2021 |
Unexpectedly Stable (Chlorocarbonyl)(N-ethoxycarbonylcarbamoyl) disulfane, and Related Compounds That Model the Zumach–Weiss–Kühle (ZWK) Reaction for Synthesis of 1, 2, 4 … G Barany, D Britton, L Chen, RP Hammer, MJ Henley, AM Schrader, ... The Journal of Organic Chemistry 80 (22), 11313-11321, 2015 | 5 | 2015 |
Nailing Down a Notoriously Elusive Cancer Target: Direct Inhibition of MYC by a Covalent Small Molecule MJ Henley, SK Doyle, AN Koehler Cell Chemical Biology 28 (1), 1-3, 2021 | 2 | 2021 |
Crystal structure of O-ethyl N-(ethoxycarbonyl) thiocarbamate MJ Henley, AM Schrader, VG Young Jr, G Barany Acta Crystallographica Section E: Crystallographic Communications 71 (10 …, 2015 | 2 | 2015 |
Garcinolic acid distinguishes between GACKIX domains and modulates interaction networks ME Breen, ST Joy, OJ Baruti, MS Beyersdorf, MJ Henley, SN De Salle, ... Chembiochem 24 (21), e202300439, 2023 | 1 | 2023 |
Crystal structures of (N-methyl-N-phenylamino)(N-methyl-N-phenylcarbamoyl) sulfide and the corresponding disulfane MJ Henley, AL Schroll, VG Young Jr, G Barany Acta Crystallographica Section E: Crystallographic Communications 71 (11 …, 2015 | 1 | 2015 |
Crystal structure of bis (N-methyl-N-phenylamino) trisulfane G Barany, MJ Henley, LA Polski, AL Schroll, VG Young Jr Acta Crystallographica Section E: Crystallographic Communications 71 (7 …, 2015 | 1 | 2015 |
Small molecule binders of the oncogenic fusion transcription factor PAX3-FOXO1 AN Koehler, S Doyle, B Leifer, M Henley, BW Schaefer, M Wachtel US Patent 11,964,022, 2024 | | 2024 |
Inhibition of CREB binding and function with a dual-targeting ligand Y Liu, ST Joy, MJ Henley, A Croskey, JA Yates, SD Merajver, AK Mapp Biochemistry 63 (1), 1-8, 2023 | | 2023 |
Preparation, Characterization, and Mechanistic Considerations for 1, 1, 1-Tri (thioacetyl) ethane and 1, 1-Di (thioacetyl) ethene ES Goebel, MJ Turcotte, MJ Henley, VG Young Jr, G Barany The Journal of Organic Chemistry 88 (11), 7535-7538, 2023 | | 2023 |
Mechanistic Insights Into the Zumach-Weiss-Kühle Synthesis of Dithiasuccinoyl (Dts)-Protected Amines MJ Henley, MJ Barany, L Chen, RP Hammer, AM Schrader, VG Young Jr, ... | | |