A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae A Hammond, R Galizi, K Kyrou, A Simoni, C Siniscalchi, D Katsanos, ... Nature biotechnology 34 (1), 78-83, 2016 | 1384 | 2016 |
A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes K Kyrou, AM Hammond, R Galizi, N Kranjc, A Burt, AK Beaghton, T Nolan, ... Nature biotechnology 36 (11), 1062-1066, 2018 | 807 | 2018 |
The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito AM Hammond, K Kyrou, M Bruttini, A North, R Galizi, X Karlsson, N Kranjc, ... PLoS genetics 13 (10), e1007039, 2017 | 282 | 2017 |
A CRISPR-Cas9 sex-ratio distortion system for genetic control R Galizi, A Hammond, K Kyrou, C Taxiarchi, F Bernardini, SM O’Loughlin, ... Scientific reports 6, 31139, 2016 | 199 | 2016 |
A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae A Simoni, AM Hammond, AK Beaghton, R Galizi, C Taxiarchi, K Kyrou, ... Nature biotechnology 38 (9), 1054-1060, 2020 | 196 | 2020 |
Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance A Hammond, X Karlsson, I Morianou, K Kyrou, A Beaghton, M Gribble, ... PLoS genetics 17 (1), e1009321, 2021 | 126* | 2021 |
Gene drives to fight malaria: current state and future directions AM Hammond, R Galizi Pathogens and global health 111 (8), 412-423, 2017 | 121 | 2017 |
Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field A Hammond, P Pollegioni, T Persampieri, A North, R Minuz, A Trusso, ... Nature Communications 12 (1), 4589, 2021 | 90 | 2021 |
Requirements for driving antipathogen effector genes into populations of disease vectors by homing A Beaghton, A Hammond, T Nolan, A Crisanti, HCJ Godfray, A Burt Genetics 205 (4), 1587-1596, 2017 | 64 | 2017 |
Gene drive for population genetic control: non-functional resistance and parental effects AK Beaghton, A Hammond, T Nolan, A Crisanti, A Burt Proceedings of the Royal Society B 286 (1914), 20191586, 2019 | 59 | 2019 |
Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito WT Garrood, N Kranjc, K Petri, DY Kim, JA Guo, AM Hammond, ... Proceedings of the National Academy of Sciences 118 (22), e2004838117, 2021 | 39 | 2021 |
The Anopheles FBN9 immune factor mediates Plasmodium species-specific defense through transgenic fat body expression ML Simões, Y Dong, A Hammond, A Hall, A Crisanti, T Nolan, ... Developmental & Comparative Immunology 67, 257-265, 2017 | 35 | 2017 |
Resistance to a CRISPR-based gene drive at an evolutionarily conserved site is revealed by mimicking genotype fixation S Fuchs, WT Garrood, A Beber, A Hammond, R Galizi, M Gribble, ... PLoS Genetics 17 (10), e1009740, 2021 | 27 | 2021 |
Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex F Bernardini, R Galizi, M Wunderlich, C Taxiarchi, N Kranjc, K Kyrou, ... Genetics 207 (2), 729-740, 2017 | 22 | 2017 |
Transgenic insects: techniques and applications MQ Benedict, MJ Scott CABI, 2022 | 20 | 2022 |
Molecular tools and genetic markers for the generation of transgenic sexing strains in Anopheline mosquitoes F Bernardini, RE Haghighat-Khah, R Galizi, AM Hammond, T Nolan, ... Parasites & vectors 11, 5-12, 2018 | 14 | 2018 |
A novel factor modulating X chromosome dosage compensation in Anopheles E Krzywinska, P Ribeca, L Ferretti, A Hammond, J Krzywinski Current Biology 33 (21), 4697-4703. e4, 2023 | 3 | 2023 |
The development of gene drives for genetic control of the malaria mosquito AM Hammond Imperial College London, 2017 | 3 | 2017 |
CRISPR-mediated cassette exchange (CriMCE): a method to introduce and isolate precise marker-less edits I Morianou, A Crisanti, T Nolan, AM Hammond The CRISPR Journal 5 (6), 868-876, 2022 | 2 | 2022 |
Sex-, tissue-and stage-specific transgene expression. AM Hammond, T Nolan Transgenic insects: techniques and applications, 29-50, 2014 | 2 | 2014 |