Circadian rhythm as a therapeutic target W Ruan, X Yuan, HK Eltzschig Nature Reviews Drug Discovery 20 (4), 287-307, 2021 | 265 | 2021 |
Effects of down-regulation of microRNA-23a on TNF-α-induced endothelial cell apoptosis through caspase-dependent pathways W Ruan, J Xu, S Li, L Yuan, R Dai Cardiovascular research 93 (4), 623-632, 2012 | 77 | 2012 |
Porous Nb-Ti-Ta alloy scaffolds for bone tissue engineering: Fabrication, mechanical properties and in vitro/vivo biocompatibility J Liu, J Ruan, L Chang, H Yang, W Ruan Materials Science and Engineering: C 78, 503-512, 2017 | 62 | 2017 |
PPAR‐γ Activation Prevents Septic Cardiac Dysfunction via Inhibition of Apoptosis and Necroptosis S Peng, J Xu, W Ruan, S Li, F Xiao Oxidative Medicine and Cellular Longevity 2017 (1), 8326749, 2017 | 62 | 2017 |
Sevoflurane pretreatment attenuates TNF-α-induced human endothelial cell dysfunction through activating eNOS/NO pathway S Li, J Xu, W Yao, H Li, Q Liu, F Xiao, MG Irwin, Z Xia, W Ruan Biochemical and biophysical research communications 460 (3), 879-886, 2015 | 44 | 2015 |
Microstructure, mechanical properties, and preliminary biocompatibility evaluation of binary Ti–Zr alloys for dental application B Wang, W Ruan, J Liu, T Zhang, H Yang, J Ruan Journal of Biomaterials Applications 33 (6), 766-775, 2019 | 43 | 2019 |
PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling J Li, C Conrad, TW Mills, NK Berg, B Kim, W Ruan, JW Lee, X Zhang, ... Journal of Experimental Medicine 218 (6), e20210008, 2021 | 40 | 2021 |
Brain‐derived neurotrophic factor attenuates septic myocardial dysfunction via eNOS/NO pathway in rats N Zeng, J Xu, W Yao, S Li, W Ruan, F Xiao Oxidative Medicine and Cellular Longevity 2017 (1), 1721434, 2017 | 27 | 2017 |
GRP78 effectively protect hypoxia/reperfusion‐induced myocardial apoptosis via promotion of the Nrf2/HO‐1 signaling pathway H Ji, F Xiao, S Li, R Wei, F Yu, J Xu Journal of cellular physiology 236 (2), 1228-1236, 2021 | 26 | 2021 |
Edaravone Improves Septic Cardiac Function by Inducing an HIF‐1α/HO‐1 Pathway C He, W Zhang, S Li, W Ruan, J Xu, F Xiao Oxidative Medicine and Cellular Longevity 2018 (1), 5216383, 2018 | 25 | 2018 |
Effect of dexmedetomidine on plasma brain-derived neurotrophic factor: A double-blind, randomized and placebo-controlled study L Yang, JM Xu, XH Jiang, W Ruan, YL Cui, L He Upsala Journal of Medical Sciences 118 (4), 235-239, 2013 | 25 | 2013 |
The hypoxia-adenosine link during myocardial ischemia—reperfusion injury W Ruan, X Ma, IH Bang, Y Liang, JD Muehlschlegel, KL Tsai, TW Mills, ... Biomedicines 10 (8), 1939, 2022 | 23 | 2022 |
Involvement of microRNA-23b-5p in the promotion of cardiac hypertrophy and dysfunction via the HMGB2 signaling pathway DB Oumarou, H Ji, J Xu, S Li, W Ruan, F Xiao, F Yu Biomedicine & Pharmacotherapy 116, 108977, 2019 | 21 | 2019 |
Hypoxia‐inducible factor‐dependent induction of myeloid‐derived netrin‐1 attenuates natural killer cell infiltration during endotoxin‐induced lung injury NK Berg, J Li, B Kim, T Mills, G Pei, Z Zhao, X Li, X Zhang, W Ruan, ... The FASEB Journal 35 (4), 2021 | 19 | 2021 |
Targeting hypoxia-inducible factors: therapeutic opportunities and challenges X Yuan, W Ruan, B Bobrow, P Carmeliet, HK Eltzschig Nature Reviews Drug Discovery 23 (3), 175-200, 2024 | 18 | 2024 |
Catastrophic cardiac events during transcatheter aortic valve replacement Y Liang, A Dhoble, A Pakanati, Y Zhao, F Kork, W Ruan, T Markham, ... Canadian Journal of Cardiology 37 (10), 1522-1529, 2021 | 17 | 2021 |
Limb remote ischemic preconditioning attenuates liver ischemia reperfusion injury by activating autophagy via modulating PPAR-γ pathway W Ruan, Q Liu, C Chen, S Li, J Xu Zhong nan da xue xue bao. Yi xue ban= Journal of Central South University …, 2016 | 16 | 2016 |
Interplay of hypoxia-inducible factors and oxygen therapy in cardiovascular medicine Y Liang, W Ruan, Y Jiang, R Smalling, X Yuan, HK Eltzschig Nature Reviews Cardiology 20 (11), 723-737, 2023 | 12 | 2023 |
Targeting myocardial equilibrative nucleoside transporter ENT1 provides cardioprotection by enhancing myeloid Adora2b signaling W Ruan, J Li, S Choi, X Ma, Y Liang, R Nair, X Yuan, TW Mills, ... JCI insight 8 (11), 2023 | 9 | 2023 |
Myeloid hypoxia-inducible factor HIF1A provides cardio-protection during ischemia and reperfusion via induction of netrin-1 KL Heck-Swain, J Li, W Ruan, X Yuan, Y Wang, M Koeppen, HK Eltzschig Frontiers in Cardiovascular Medicine 9, 970415, 2022 | 9 | 2022 |