Why 90% of clinical drug development fails and how to improve it? D Sun, W Gao, H Hu, S Zhou Acta Pharmaceutica Sinica B 12 (7), 3049-3062, 2022 | 707 | 2022 |
Novel thermo-sensitive hydrogel system with paclitaxel nanocrystals: High drug-loading, sustained drug release and extended local retention guaranteeing better efficacy and … Z Lin, W Gao, H Hu, K Ma, B He, W Dai, X Wang, J Wang, X Zhang, ... Journal of Controlled Release 174, 161-170, 2014 | 209 | 2014 |
What Went Wrong with Anticancer Nanomedicine Design and How to Make It Right D Sun, S Zhou, W Gao ACS nano 14 (10), 12281-12290, 2020 | 175 | 2020 |
Hydrophobic penetrating peptide PFVYLI-modified stealth liposomes for doxorubicin delivery in breast cancer therapy D Cai, W Gao, B He, W Dai, H Zhang, X Wang, J Wang, X Zhang, Q Zhang Biomaterials 35 (7), 2283-2294, 2014 | 111 | 2014 |
Polyamidoamine dendrimers as potential drug carriers for enhanced aqueous solubility and oral bioavailability of silybin X Huang, Z Wu, W Gao, Q Chen, B Yu Drug development and industrial pharmacy 37 (4), 419-427, 2011 | 69 | 2011 |
A folate modified pH sensitive targeted polymeric micelle alleviated systemic toxicity of doxorubicin (DOX) in multi-drug resistant tumor bearing mice X Li, X Yang, Z Lin, D Wang, D Mei, B He, X Wang, X Wang, Q Zhang, ... European Journal of Pharmaceutical Sciences 76, 95-101, 2015 | 65 | 2015 |
The use of α-conotoxin ImI to actualize the targeted delivery of paclitaxel micelles to α7 nAChR-overexpressing breast cancer D Mei, Z Lin, J Fu, B He, W Gao, L Ma, W Dai, H Zhang, X Wang, J Wang, ... Biomaterials 42, 52-65, 2015 | 61 | 2015 |
Andrographolide-loaded PLGA-PEG-PLGA micelles to improve its bioavailability and anticancer efficacy J Zhang, Y Li, W Gao, MA Repka, Y Wang, M Chen Expert opinion on drug delivery 11 (9), 1367-1380, 2014 | 55 | 2014 |
Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice Y Song, L Bugada, R Li, H Hu, L Zhang, C Li, H Yuan, KK Rajanayake, ... Science Translational Medicine 14 (643), eabl3649, 2022 | 49 | 2022 |
Reappraisal of anticancer nanomedicine design criteria in three types of preclinical cancer models for better clinical translation X Luan, H Yuan, Y Song, H Hu, B Wen, M He, H Zhang, Y Li, F Li, P Shu, ... Biomaterials 275, 120910, 2021 | 49 | 2021 |
Transferrin receptor-targeted pH-sensitive micellar system for diminution of drug resistance and targetable delivery in multidrug-resistant breast cancer W Gao, G Ye, X Duan, X Yang, VC Yang International Journal of Nanomedicine, 1047-1064, 2017 | 49 | 2017 |
Hyaluronic Acid Stabilized Iodine-Containing Nanoparticles with Au Nanoshell Coating for X-ray CT Imaging and Photothermal Therapy of Tumors X Liu, C Gao, J Gu, Y Jiang, X Yang, S Li, W Gao, T An, H Duan, J Fu, ... ACS applied materials & interfaces 8 (41), 27622-27631, 2016 | 39 | 2016 |
A multi-functionalized nanocomposite constructed by gold nanorod core with triple-layer coating to combat multidrug resistant colorectal cancer Y Jiang, Z Guo, J Fang, B Wang, Z Lin, ZS Chen, Y Chen, N Zhang, ... Materials Science and Engineering: C 107, 110224, 2020 | 34 | 2020 |
Smart nanoparticles undergo phase transition for enhanced cellular uptake and subsequent intracellular drug release in a tumor microenvironment G Ye, Y Jiang, X Yang, H Hu, B Wang, L Sun, VC Yang, D Sun, W Gao ACS applied materials & interfaces 10 (1), 278-289, 2018 | 32 | 2018 |
A nanomedicine based combination therapy based on QLPVM peptide functionalized liposomal tamoxifen and doxorubicin against Luminal A breast cancer X Wang, X Chen, X Yang, W Gao, B He, W Dai, H Zhang, X Wang, J Wang, ... Nanomedicine: Nanotechnology, Biology and Medicine 12 (2), 387-397, 2016 | 32 | 2016 |
Gold nanorods with silica shell and pamam dendrimers for efficient photothermal therapy and low toxic codelivery of anticancer drug and sirna Q Zhang, L Wang, Y Jiang, W Gao, Y Wang, X Yang, X Yang, Z Liu Advanced Materials Interfaces 4 (24), 1701166, 2017 | 31 | 2017 |
A comparative investigation between paclitaxel nanoparticle-and nanocrystal-loaded thermosensitive PECT hydrogels for peri-tumoural administration Z Lin, S Xu, W Gao, H Hu, M Chen, Y Wang, B He, W Dai, H Zhang, ... Nanoscale 8 (44), 18782-18791, 2016 | 27 | 2016 |
A personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor B Wang, S Wu, Z Lin, Y Jiang, Y Chen, ZS Chen, X Yang, W Gao International Journal of Nanomedicine, 8411-8427, 2018 | 23 | 2018 |
The co-delivery of a low-dose P-glycoprotein inhibitor with doxorubicin sterically stabilized liposomes against breast cancer with low P-glycoprotein expression W Gao, Z Lin, M Chen, X Yang, Z Cui, X Zhang, L Yuan, Q Zhang International journal of nanomedicine, 3425-3437, 2014 | 21 | 2014 |
Synthesis of hydrophilic microspheres with LCST close to body temperature for controlled dual‐sensitive drug release UG Spizzirri, F Iemma, F Puoci, F Xue, W Gao, G Cirillo, M Curcio, ... Polymers for Advanced Technologies 22 (12), 1705-1712, 2011 | 21 | 2011 |