Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2 SJ Humphrey, G Yang, P Yang, DJ Fazakerley, J Stöckli, JY Yang, ... Cell metabolism 17 (6), 1009-1020, 2013 | 438 | 2013 |
A positive feedback loop between Akt and mTORC2 via SIN1 phosphorylation G Yang, DS Murashige, SJ Humphrey, DE James Cell reports 12 (6), 937-943, 2015 | 358 | 2015 |
Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling Y Wang, D Du, L Fang, G Yang, C Zhang, R Zeng, A Ullrich, F Lottspeich, ... The EMBO journal 25 (21), 5058-5070, 2006 | 104 | 2006 |
Aberrant splicing of Hugl-1 is associated with hepatocellular carcinoma progression X Lu, X Feng, X Man, G Yang, L Tang, D Du, F Zhang, H Yuan, Q Huang, ... Clinical cancer research 15 (10), 3287-3296, 2009 | 99 | 2009 |
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ... Nature communications 10 (1), 5486, 2019 | 88 | 2019 |
Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo M Kleinert, L Sylow, DJ Fazakerley, JR Krycer, KC Thomas, AJ Oxbøll, ... Molecular metabolism 3 (6), 630-641, 2014 | 82 | 2014 |
Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry BL Parker, G Yang, SJ Humphrey, R Chaudhuri, X Ma, S Peterman, ... Science signaling 8 (380), rs6-rs6, 2015 | 73 | 2015 |
Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair L Fang, YG Wang, D Du, G Yang, T Tak Kwok, S Kai Kong, B Chen, ... Cell research 17 (2), 100-116, 2007 | 59 | 2007 |
Personalized phosphoproteomics identifies functional signaling EJ Needham, JR Hingst, BL Parker, KR Morrison, G Yang, J Onslev, ... Nature Biotechnology 40 (4), 576-584, 2022 | 54 | 2022 |
Proteomic, functional and motif‐based analysis of C‐terminal Src kinase‐interacting proteins G Yang, Q Li, S Ren, X Lu, L Fang, W Zhou, F Zhang, F Xu, Z Zhang, ... Proteomics 9 (21), 4944-4961, 2009 | 38 | 2009 |
Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis AL Kearney, DM Norris, M Ghomlaghi, M Kin Lok Wong, SJ Humphrey, ... Elife 10, e66942, 2021 | 37 | 2021 |
A novel PHD-finger protein 14/KIF4A complex overexpressed in lung cancer is involved in cell mitosis regulation and tumorigenesis L Zhang, Q Huang, J Lou, L Zou, Y Wang, P Zhang, G Yang, J Zhang, ... Oncotarget 8 (12), 19684, 2017 | 33 | 2017 |
The conservation pattern of short linear motifs is highly correlated with the function of interacting protein domains S Ren, G Yang, Y He, Y Wang, Y Li, Z Chen BMC genomics 9, 1-13, 2008 | 30 | 2008 |
RagC phosphorylation autoregulates mTOR complex 1 G Yang, SJ Humphrey, DS Murashige, D Francis, QP Wang, KC Cooke, ... The EMBO Journal 38 (3), e99548, 2019 | 29 | 2019 |
Depletion of PHF14, a novel histone-binding protein gene, causes neonatal lethality in mice due to respiratory failure Q Huang, L Zhang, Y Wang, C Zhang, S Zhou, G Yang, Z Li, X Gao, ... Acta Biochim Biophys Sin 45 (8), 622-633, 2013 | 29 | 2013 |
Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1 M Ghomlaghi, G Yang, SY Shin, DE James, LK Nguyen PLoS computational biology 17 (9), e1008513, 2021 | 19 | 2021 |
Dissecting the biology of mTORC1 beyond rapamycin G Yang, D Francis, JR Krycer, M Larance, Z Zhang, CJ Novotny, ... Science signaling 14 (701), eabe0161, 2021 | 17 | 2021 |
Structural insights into Ras regulation by SIN1 Y Zheng, L Ding, X Meng, M Potter, AL Kearney, J Zhang, J Sun, ... Proceedings of the National Academy of Sciences 119 (19), e2119990119, 2022 | 16 | 2022 |
CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion Z Zhang, W Li, G Yang, X Lu, X Qi, S Wang, C Cao, P Zhang, J Ren, ... Cell discovery 6 (1), 92, 2020 | 15 | 2020 |
Membrane topology of trafficking regulator of GLUT4 1 (TRARG1) X Duan, JR Krycer, KC Cooke, G Yang, DE James, DJ Fazakerley Biochemistry 57 (26), 3606-3615, 2018 | 8 | 2018 |